Review: could Benadryl cause Depression?


Summary

Depression is found among people who take Benadryl, especially for people who are female, 40-49 old , have been taking the drug for < 1 month, also take medication Zometa, and have Pain . We study 26,574 people who have side effects while taking Benadryl from FDA and social media. Among them, 967 have Depression. Find out below who they are, when they have Depression and more.

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Benadryl

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in hypersensitivity. (latest outcomes from Benadryl 29,242 users)

Depression

Depression has been reported by people with suicidal ideation, drug ineffective, drug exposure during pregnancy, insomnia, fatigue (latest reports from 245,188 Depression patients).

On Jul, 25, 2016

26,574 people reported to have side effects when taking Benadryl.
Among them, 967 people (3.64%) have Depression


Number of reports submitted per year:

Could Benadryl cause Depression?

Time on Benadryl when people have Depression *:

  • < 1 month: 76.92 %
  • 1 - 6 months: 3.08 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 1.54 %
  • 2 - 5 years: 6.15 %
  • 5 - 10 years: 6.15 %
  • 10+ years: 6.15 %

Gender of people who have Depression when taking Benadryl *:

  • female: 65.94 %
  • male: 34.06 %

Age of people who have Depression when taking Benadryl *:

  • 0-1: 0.0 %
  • 2-9: 0.38 %
  • 10-19: 3.7 %
  • 20-29: 8.55 %
  • 30-39: 12.12 %
  • 40-49: 28.57 %
  • 50-59: 25.64 %
  • 60+: 21.05 %

Severity if Depression when taking Benadryl **:

  • least: 0.0 %
  • moderate: 54.55 %
  • severe: 36.36 %
  • most severe: 9.09 %

How people recovered from Depression **:

  • while on drug: 0.0 %
  • after off the drug: 14.29 %
  • not yet: 85.71 %

Top conditions involved for these people *:

  • Pain (130 people)
  • Depression (91 people)
  • Hypertension (72 people)
  • Coronary Artery Bypass (61 people)
  • Multiple Myeloma (47 people)

Top co-used drugs for these people *:

  • Zometa (233 people)
  • Prilosec (191 people)
  • Oxycontin (178 people)
  • Lasix (176 people)
  • Ativan (176 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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