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Review: could Benadryl cause Hallucination?

Summary: Hallucination could be caused by Benadryl, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take Zometa, and have Pain.

We study 26,199 people who have side effects while taking Benadryl from FDA and social media. Among them, 338 have Hallucination. Find out below who they are, when they have Hallucination and more.

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On Apr, 13, 2014: 26,199 people reported to have side effects when taking Benadryl. Among them, 338 people (1.29%) have Hallucination. They amount to 0.20% of all the 167,340 people who have Hallucination on eHealthMe.

Trend of Hallucination in Benadryl reports

Time on Benadryl when people have Hallucination * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Hallucination79.59%0.00%14.29%4.08%2.04%0.00%0.00%

Gender of people who have Hallucination when taking Benadryl * :

FemaleMale
Hallucination61.30%38.70%

Age of people who have Hallucination when taking Benadryl * :

0-12-910-1920-2930-3940-4950-5960+
Hallucination0.00%4.01%9.36%2.01%20.07%17.73%9.70%37.12%

Severity of Hallucination when taking Benadryl ** :

leastmoderateseveremost severe
Hallucination0.00%0.00%66.67%33.33%

How people recovered from Hallucination ** :

while on the drugafter off the drugnot yet
Hallucination33.33%0.00%66.67%

Top conditions involved for these people * :

  1. Pain (44 people, 13.02%)
  2. Hypertension (41 people, 12.13%)
  3. Multiple myeloma (40 people, 11.83%)
  4. Gastrooesophageal reflux disease (28 people, 8.28%)
  5. Seborrhoeic dermatitis (26 people, 7.69%)

Top co-used drugs for these people * :

  1. Zometa (87 people, 25.74%)
  2. Ativan (87 people, 25.74%)
  3. Aspirin (74 people, 21.89%)
  4. Albuterol (66 people, 19.53%)
  5. Compazine (61 people, 18.05%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

Comments for this study:

Norman (3 years ago):

I used to take Benadryl because I knew it would make me hallucinate. Sometimes the hallucinations would be overwhelming to the point that I had to go to the hospital and the whole situation fealt like a loosely controlable lucid dream. About the only thing I could comprehend was that I knew not to sign the 3 day watch paper. The funny thing was the nezt day when I saw the paperwork that I filled out at the hospital was complete jiberish.
Reply the comment

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Related topic: Benadryl, Hallucination

You can also:

On eHealthMe, Benadryl (diphenhydramine hydrochloride) is often used for allergies. Find out below the conditions Benadryl is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Benadryl used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (7 months ago):

  • I took all the medicines like I am supposed to at night and I used th mouthwash and about 30 minutes later I started to hallucinate. is the mixture of the medicine that caused me to hallucinate

    Reply

  • From this study (1 year ago):

  • I was admitted to hospital for four days due to the adverse effects from these medications. On the last day, I begged them to let me out even though I was not better, so I could be with my family. I have to walk with a cane to help stabilize me, because I have fallen several times. I still have hallucinations where I see stuff on the walls and floors that are not there. I also suffered double and trouble focusing my eyes, this has for the most part disappeared.

    Reply

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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