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Home > Benadryl > Headache > Benadryl and Headache

Review: could Benadryl cause Headache?

Summary: Headache is found among people who take Benadryl, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take medication Aspirin, and have Pain.

We study 26,402 people who have side effects while taking Benadryl from FDA and social media. Among them, 1,519 have Headache. Find out below who they are, when they have Headache and more.

You are not alone: join a mobile support group for people who take Benadryl and have Headache >>>

Benadryl

Benadryl (latest outcomes from 29,359 users) has active ingredients of diphenhydramine hydrochloride. It is often used in allergies.

Trend of benadryl reports

Headache

Headache (pain in head) (latest reports from 199,069 patients) has been reported by people with multiple sclerosis, depression, high blood pressure, rheumatoid arthritis, osteoporosis.

Trend of Headache reports

On Nov, 12, 2014: 26,394 people reported to have side effects when taking Benadryl. Among them, 1,707 people (6.47%) have Headache.

Trend of Headache in Benadryl reports

Time on Benadryl when people have Headache * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Headache76.67%10.00%0.83%1.67%4.17%6.67%0.00%

Gender of people who have Headache when taking Benadryl * :

FemaleMale
Headache74.40%25.60%

Age of people who have Headache when taking Benadryl * :

0-12-910-1920-2930-3940-4950-5960+
Headache0.00%3.07%7.08%7.02%13.01%23.23%22.96%23.64%

Severity of Headache when taking Benadryl ** :

leastmoderateseveremost severe
Headache4.76%52.38%28.57%14.29%

How people recovered from Headache ** :

while on the drugafter off the drugnot yet
Headache7.14%28.57%64.29%

Top conditions involved for these people * :

  1. Pain (165 people, 9.67%)
  2. Multiple sclerosis (124 people, 7.26%)
  3. Hypertension (104 people, 6.09%)
  4. Depression (100 people, 5.86%)
  5. Crohn's disease (77 people, 4.51%)

Top co-used drugs for these people * :

  1. Aspirin (226 people, 13.24%)
  2. Zometa (216 people, 12.65%)
  3. Ambien (192 people, 11.25%)
  4. Decadron (191 people, 11.19%)
  5. Zofran (184 people, 10.78%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Headache while taking Benadryl?

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  • Dyphenhydramine and headaches horrible going one almost 24 hours a day for 4 weeks and cant get them to stop, now looking for cause . think its the dyphenhydramine im taking to help me sleep .
    (Posted by a 63 year old woman who has Headaches, and takes Diphenhydramine Hydrochloride)
    have been taking 3 dyphenhydramine for some time to help me sleep , just in last few weeks began having severe headache almost all the time.. cant get it to go away. just found out it can cause headache and am going to lower my intake to one per night and see if my headaches get better. am taking mi ...

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    Whenever I use Raspberry Ketones 500mg capsules (1 a day) I get reddening of the tops of my cheeks coupled with muscle tightening/twitching of the cheek muscles closest to the nose (the muscles that contract if someone blows in your eyes) and the muscles at the bridge of nose at times too. Both sets ...

  • Benadryl completed suicide 50 year old
    (Posted by a 50 year old woman who has Completed Suicide, and takes Alcohol, Methenamine Hippurate, Xanax, Benadryl)
    My mother comitted suicide by taking a bottle of Benadryl. She also had been drinking, she had taken xanax and drank beer, she also took 300 Benadryl pills and started having seizures and went to the hospital was brain dead and her heart stopped the next morning.

  • Had nms in 2005, will trileptal increase chance of recurrence?
    (Posted by a 62 year old woman who has Narcolepsy, Prinzmetal's Angina , Antiphospholipid Syndrome, High Blood Pressure, Obsessive-compulsive Personality Disorder, Cyclic Vomiting Syndrome, Migraine With Aura, Herniated Intervertebral Disk, Osteoarthritis, Fibromyalgia, Rheumatoid Arthritis, Diabetes Mellitus Insulin-dependent, Bipolar I Disorder, and takes Benadryl, Baclofen, Plaquenil, Nitro-bid, Maxalt-mlt, Imitrex, Zofran Odt, Ms Contin, Clonidine, Amlodipine Besylate, Novolog Flexpen, Levemir Flexpen, Halcion, Valium, Primidone, Neurontin, Trileptal)
    In 2005 I had NMS, which was not detected by my drs for 4 months. I'd been on Lexapro & Seroquel for 2 yrs, but was weaned from Lexapro & placed on Lamictal 3/05. Began getting low-grade fevers, which I was told were not caused by the Lamictal. I quit taking it anyway, fevers (along with uncontrolla ...

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