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Review: could Benadryl cause Headache?

Summary: Headache could be caused by Benadryl, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take Aspirin, and have Pain.

We study 26,199 people who have side effects while taking Benadryl from FDA and social media. Among them, 1,703 have Headache. Find out below who they are, when they have Headache and more.

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Benadryl

Benadryl (latest outcomes from 29,278 users) has active ingredients of diphenhydramine hydrochloride. It is often used in allergies.

Headache

Headache (pain in head) (latest reports from 1,203,664 patients) has been reported by people with multiple sclerosis, high blood pressure, depression, rheumatoid arthritis, osteoporosis.

On Apr, 11, 2014: 26,199 people reported to have side effects when taking Benadryl. Among them, 1,703 people (6.50%) have Headache. They amount to 0.14% of all the 1,200,473 people who have Headache on eHealthMe.

Trend of Headache in Benadryl reports

Time on Benadryl when people have Headache * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Headache77.78%10.26%0.85%1.71%3.42%5.98%0.00%

Gender of people who have Headache when taking Benadryl * :

FemaleMale
Headache74.45%25.55%

Age of people who have Headache when taking Benadryl * :

0-12-910-1920-2930-3940-4950-5960+
Headache0.00%3.07%7.04%7.04%12.98%23.22%22.95%23.70%

Severity of Headache when taking Benadryl ** :

leastmoderateseveremost severe
Headache5.88%58.82%17.65%17.65%

How people recovered from Headache ** :

while on the drugafter off the drugnot yet
Headache10.00%40.00%50.00%

Top conditions involved for these people * :

  1. Pain (165 people, 9.69%)
  2. Multiple sclerosis (124 people, 7.28%)
  3. Hypertension (104 people, 6.11%)
  4. Depression (100 people, 5.87%)
  5. Crohn's disease (77 people, 4.52%)

Top co-used drugs for these people * :

  1. Aspirin (226 people, 13.27%)
  2. Zometa (216 people, 12.68%)
  3. Ambien (192 people, 11.27%)
  4. Decadron (191 people, 11.22%)
  5. Zofran (184 people, 10.80%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Benadryl, Headache

You can also:

On eHealthMe, Benadryl (diphenhydramine hydrochloride) is often used for allergies. Find out below the conditions Benadryl is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Benadryl used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (2 days ago):

  • Been I'll for 9 months. Just recently found pneumonia. Can't afford dermatologist and do for doesn't know what the hives are. You can write with your finger on my skin and it will show up.

    Reply

  • From this study (4 months ago):

  • The sinus pain occurs when I drink alcohol most of the time but does occurs without the use of alcohol beverages. I get some relief by using a very hot towel for about 30 minutes and the Flunisolide. My doctor has given me MRI's, CAT Scans, blood work, eye pressure test and stress tests. I am retired military and I have traveled all over the world. The sinus pain began in Texas in 2005 after a severe sinus infection that was not treated properly by my ex-doctor.

    Reply

  • From this study (2 years ago):

  • Head feels like it is collapsing into my ears. Feel nauseaous.

    Reply

Can you answer these questions (what is this?):

More questions for: Benadryl, Headache

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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