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Review: could Benadryl cause Hives?





Summary: Hives is found among people who take Benadryl, especially for people who are female, 20-29 old, have been taking the drug for 1 - 6 months, also take medication Prednisone, and have Hives.

We study 26,402 people who have side effects while taking Benadryl from FDA and social media. Among them, 14 have Hives. Find out below who they are, when they have Hives and more.

You are not alone: join a mobile support group for people who take Benadryl and have Hives >>>

Benadryl

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in allergies. (view latest outcomes from 29,367 users)

Hives

Hives has been reported by people with high blood pressure, depression, high blood cholesterol, stress and anxiety, attention deficit hyperactivity disorder.(latest reports from Hives 581 patients)

On Dec, 13, 2014: 26,402 people reported to have side effects when taking Benadryl. Among them, 14 people (0.05%) have Hives.

Trend of Hives in Benadryl reports

Time on Benadryl when people have Hives * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Hives36.36%36.36%0.00%9.09%0.00%9.09%9.09%

Gender of people who have Hives when taking Benadryl * :

FemaleMale
Hives57.14%42.86%

Age of people who have Hives when taking Benadryl * :

0-12-910-1920-2930-3940-4950-5960+
Hives0.00%0.00%7.14%28.57%7.14%28.57%7.14%21.43%

Severity of Hives when taking Benadryl ** :

leastmoderateseveremost severe
Hives7.14%57.14%28.57%7.14%

How people recovered from Hives ** :

while on the drugafter off the drugnot yet
Hives0.00%50.00%50.00%

Top conditions involved for these people * :

  1. Hives (6 people, 42.86%)
  2. High blood pressure (5 people, 35.71%)
  3. Headache (2 people, 14.29%)
  4. High blood cholesterol (2 people, 14.29%)
  5. Allergies (2 people, 14.29%)

Top co-used drugs for these people * :

  1. Prednisone (3 people, 21.43%)
  2. Lipitor (2 people, 14.29%)
  3. Adderall (2 people, 14.29%)
  4. Atenolol (2 people, 14.29%)
  5. Albuterol sulfate (2 people, 14.29%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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You may be interested at these reviews (Write a review):

  • Dyphenhydramine and headaches horrible going one almost 24 hours a day for 4 weeks and cant get them to stop, now looking for cause . think its the dyphenhydramine im taking to help me sleep .
    have been taking 3 dyphenhydramine for some time to help me sleep , just in last few weeks began having severe headache almost all the time.. cant get it to go away. just found out it can cause headache and am going to lower my intake to one per night and see if my headaches get better. am taking migrane meds and that hasnt helped a bit so think its not migranes im having. some other reason.
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  • Nightmare on benadryl
    After 5 nights without sleep and not having past bad dreams, the last 2 night's taking walfrin sub, for benadryl has terrified THE WORST OF WORST dream in my 55 years. Peaceful start of a dream then seeing myself or family,friends get slottard.crazy thing is I don't watch scary movies or the news. I think I'm going to pass on this meds, and pass out next time :) thank you,God bless
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  • Benadryl completed suicide 50 year old
    My mother comitted suicide by taking a bottle of Benadryl. She also had been drinking, she had taken xanax and drank beer, she also took 300 Benadryl pills and started having seizures and went to the hospital was brain dead and her heart stopped the next morning.
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  • Had nms in 2005, will trileptal increase chance of recurrence?
    In 2005 I had NMS, which was not detected by my drs for 4 months. I'd been on Lexapro & Seroquel for 2 yrs, but was weaned from Lexapro & placed on Lamictal 3/05. Began getting low-grade fevers, which I was told were not caused by the Lamictal. I quit taking it anyway, fevers (along with uncontrollable shivering) continued & got higher. By 5/05 my temps were reaching 105 deg F. Husband said I became combative, refused to go to hospital. Early June/05 he came home to find me wrapped in blankets, with a temp over 105 F. He tried to place me in a tub of cold water, said I was rigid & screamed when he tried to move me. I was in the tub, speaking "in tongues" (his description, I have no memory of this). He called 911, took me to hospital. I woke, no idea where I was or why. After a lumbar puncture & 2 days in ICU I went home. The fevers continued...2 weeks later he came home to find me wrapped in sheets, towels, blankets, with the heat on full (it was in the 90's outside) he called ambulance again. I awoke to find myself under an ice blanket with nurses pushing large vials of dantrolene into both arms, several liters. Another LP, a stint in ICU...this time they told me it was NMS. The dr who dxd me said he was surprised I was alive, & not a vegetable, as my temp had peaked at 109 deg F. I suffered brain damage; short-term memory loss, brain can't control my body temp, my blood pressure went up. An arteriogram showed completely healthy heart & arteries, no plaque at all. I lost all body fat as well as some muscle mass. The fevers continued even after stopping the Seroquel. I visited my PCP for a checkup in 9/05, temp was normal. I started shuddering, my temp went up a full degree every 5 minutes. PCP admitted me to ER, my heart rate was over 272 B/M; they stopped my heart 3 times to "reset" it, which didn't work. I spent 3 days in hospital. Several months later my P doc tried me on Lamictal alone; I got Stevens-Johnson syndrome. I stopped the drug as soon as the signs appeared. I've been untreated, except for Neurontin & Primidone, until my manic episodes became unlivable. 3 weeks ago I went 8 days with no sleep, became psychotic. My P doc gave me Trileptal, which has evened my moods, but I've been getting low-grade fevers (highest was 103.6). Would having had NMS in the past make me more prone to falling to it again with the Trileptal? It's the only new med I've taken in over a year.
    Reply
  • Allergic to ivp dye bad reaction to pyridium
    I am allergic to IVP dye (Iodine) I had discovered this over 20 years ago when I had kidney stones and was injected with the IVP. I was asked beforehand if I was allergic to shellfish and told them I didn't know since at the time I had never eaten seafood. After the injected me and walked out of the room my throat swelled and I couldn't breathe, hives formed I had to grab whatever I could to throw around the room to get someones attention. They rushed in and gave me a shot of adrenaline. WHEW!! I had taken Pyridium on many occasions in the following years with no problems.Last night I took one and had a SEVERE reaction. I think the problem is I had not eaten much in 2 days and the iodine hit me HARD! :-/ first I started itching allover, had what looked like small mosquito bites all over my arms, My hands swelled and I felt hot then I had what felt like heartburn, chest pains right between my breasts and deep down that would come and fade ALL NIGHT and to top it off I was on a date! This morning I feel fine. I had taken about 4 tablespoons of Benadryl and later chewed some aspirin thinking heart attack!! :-/
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  • Past month...hives/welts appear on one location of my body for no apparent reason. They usually occur at times when I haven't eaten anything for 5-6 hours or upon waking up when I haven't eaten anything for at least 8 hr. I have had the hives/welts appear on my face (lips, cheek, nostrils), on my ...
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