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Review: could Benadryl cause Itching?

Summary: Itching is found among people who take Benadryl, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take medication Prednisone, and have Itching. We study 26,443 people who have side effects while taking Benadryl from FDA and social media. Among them, 1,583 have Itching. Find out below who they are, when they have Itching and more.

You are not alone: join a support group for people who take Benadryl and have Itching >>>

Personalized health information: on eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA and social media since 1977. Our tools are free and anonymous. 66 million people have used us. 200+ peer-reviewed medical journals have referenced our original studies. Start now >>>

 

Benadryl

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in allergies. (latest outcomes from 29,405 Benadryl users)

Itching

Itching has been reported by people with high blood cholesterol, high blood pressure, rheumatoid arthritis, pain, multiple sclerosis. (latest reports from 88,320 Itching patients)

On May, 13, 2015: 26,443 people reported to have side effects when taking Benadryl. Among them, 1,583 people (5.99%) have Itching.

Trend of Itching in Benadryl reports

Time on Benadryl when people have Itching * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Itching92.72%3.88%0.49%1.46%0.00%0.49%0.97%

Gender of people who have Itching when taking Benadryl * :

FemaleMale
Itching71.85%28.15%

Age of people who have Itching when taking Benadryl * :

0-12-910-1920-2930-3940-4950-5960+
Itching0.00%1.53%3.12%5.62%13.18%18.52%25.66%32.39%

Severity of Itching when taking Benadryl ** :

leastmoderateseveremost severe
Itching0.00%43.75%37.50%18.75%

How people recovered from Itching ** :

while on the drugafter off the drugnot yet
Itching0.00%12.50%87.50%

Top conditions involved for these people * :

  1. Pruritus (112 people, 7.08%)
  2. Multiple sclerosis (90 people, 5.69%)
  3. Crohn's disease (76 people, 4.80%)
  4. Pain (68 people, 4.30%)
  5. Rheumatoid arthritis (66 people, 4.17%)

Top co-used drugs for these people * :

  1. Prednisone (240 people, 15.16%)
  2. Remicade (164 people, 10.36%)
  3. Decadron (149 people, 9.41%)
  4. Aspirin (146 people, 9.22%)
  5. Coumadin (126 people, 7.96%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of benadryl and itching on

Do you have Itching while taking Benadryl?

 

You are not alone! Join a support group on :
- support group for people who take Benadryl and have Itching
- support group for people who take Benadryl
- support group for people who have Itching

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Comments from related studies:

  • From this study (4 months ago):

  • Severe rash on legs and body 6 weeks ago faded considerably at this time, now I have small red flat spots on body and few on arms and legs some have developed lumps under the skin

    Reply

  • From this study (12 months ago):

  • Itching in extremeties with no rash apparent. Eyes watery and burning. Twitching is in left eyelid. Itching started 8 days ago. Lotion does not help much. Diphenhydramine does not help much.

    Reply

  • From this study (3 years ago):

  • Itching and breaking out suddenly after Varicella vaccine on Mon. A little while ago, I just began itching severly. I went to check the mirror & I have small bumps all over the bottom of my face, by the chin, corners of mouth and seems to be spreading across face with mild bumpy areas on forehead/upper face. i have lumbago, neuralgia & osteoarthritis/ddd in my lower back, right side, with pain shooting down my leg. I have a high sensitivity to pain and it feels like microscopic bugs are biting my arms, legs & upper back and thighs. Help, please. Do you think this is an adverse reaction to the Varicella vaccine? I've never had chickenpox nor the vaccine. I haven't yet taken the Benadryl but wanted to make sure it was safe before I did.

    Reply

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