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Review: could Benadryl cause Leg cramps?

Summary: Leg cramps could be caused by Benadryl, especially for people who are male, 2-9 old, have been taking the drug for 1 - 6 months, also take Ibuprofen, and have Fever.

We study 26,199 people who have side effects while taking Benadryl from FDA and social media. Find out below who they are, when they have Leg cramps and more.

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On Apr, 6, 2014: 26,189 people reported to have side effects when taking Benadryl. Among them, 1 people (0.00%) has Leg Cramps. They amount to 0.07% of all the 1,490 people who have Leg Cramps on eHealthMe.

Trend of Leg cramps in Benadryl reports

Time on Benadryl when people have Leg cramps * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Leg cramps0.00%100.00%0.00%0.00%0.00%0.00%0.00%

Gender of people who have Leg cramps when taking Benadryl * :

FemaleMale
Leg cramps0.00%100.00%

Age of people who have Leg cramps when taking Benadryl * :

0-12-910-1920-2930-3940-4950-5960+
Leg cramps0.00%100.00%0.00%0.00%0.00%0.00%0.00%0.00%

Severity of Leg cramps when taking Benadryl ** :

leastmoderateseveremost severe
Leg cramps0.00%100.00%0.00%0.00%

How people recovered from Leg cramps ** :

n/a

Top conditions involved for these people * :

  1. Fever (1 people, 100.00%)

Top co-used drugs for these people * :

  1. Ibuprofen (1 people, 100.00%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

Comments for this study:

Jennifer Clark (2 years ago):

When I take Benadryl, my legs and arms cramp. It's a lot like restless leg syndrom. Luckily, I found that magnesium citrate taken 3 times per day helps to alleviate the symptons,
Reply the comment

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On eHealthMe, Benadryl (diphenhydramine hydrochloride) is often used for allergies. Find out below the conditions Benadryl is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

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Comments from related studies:

  • From this study (3 weeks ago):

  • Leg jerking as I fall asleep after taking 50 mg Benadryl

    Reply

  • From this study (8 months ago):

  • Mother has made claims of illness for child since age 2. Has said Dr. thinks he has IBS - age 2. May have a liver disease - age 3. Had rashes that cleared up when with us, recurred when returned home. Told husband Dr. said he had Eczema and would have to take medication the rest of his life. Condition has not recurred since. Severe constipation (hard, dry)when comes to our home, clears up within a few days (up to age 4). Child told our niece his mother always says he's sick and gives him medicine (age 4). Has had bronchial conditions and severe nasal discharges at his mothers that cleared up when with us, she gives/gave benadryl frequently. He has had dry skin conditions, rashes clear up when with us. Fever seizures (since he was 2) at home that never occurred when with us. Child went without a Dr from December of 2012 to August 2013. Only illness during that time was a fall requiring stitches in his chin. She left the stitches in until the wound healed, keeping it covered with bandage. Became angry with husband and he received a letter from her attorney accusing him of not keeping a serious wound covered, among other false statements. After getting a doctor in August, just at the time when the child is scheduled to begin school, child becomes ill with a "rash", slurred speech, and fever seizure, took him to a local hospital who diagnosed henoch-schonlein purpura (he did not have high temp at hospital). She requested child be referred to a childrens hospital. They sent her home. Next day she went to her newly acquired doctor who gave her the referral to Children's Hospital. His mother has stated SHE has heart problems, had to have biopsies on her liver for cancer, claimed to have a "pace-maker" put in. Made/makes frequent trips to various hospitals, coming home with catheters hanging down her legs, wearing dresses so the bag is visible. Same with IV -stints? Left in her arm secured by bandages. She has told me she was almost a nurse (went to classes a few months). Was very up on medical terms and conditions, but I notice that recently she is behaving like she doesn't know anything (I've mentioned Munchhausen to my husband many times and he has told that to her recently) She told my husband after the pace maker the her Doctors say she has three years to live. That was two years ago (and just stated recently when question about her health and being able to care for the child with a bad heart, she claims it's a bladder one). Claimed she had Fibro...I am afraid she is Munchhausen and may be making the baby sick. No one listens to me. There is many more symptoms from both the mother and child. Too many to list here. Please tell me what you think is going on with the child. I tried calling hotline and all the woman said was, "Are you a doctor?" The mother called yesterday and said the child is sick again. I had talked to the mother earlier and mentioned my husband was with his other son's mother and may be staying overnight with her. She is very jealous of the other son and has made statements that my husband loves him more. A couple hours later she is calling saying the boy is sick again.

    Reply

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