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Review: could Benadryl cause Low blood pressure (Hypotension)?

Summary: Low blood pressure is found among people who take Benadryl, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take medication Decadron, and have Pain. We study 26,443 people who have side effects while taking Benadryl from FDA and social media. Among them, 1,458 have Low blood pressure. Find out below who they are, when they have Low blood pressure and more.

You are not alone: join a support group for people who take Benadryl and have Low blood pressure >>>

Personalized health information: on eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA and social media since 1977. Our tools are free and anonymous. 66 million people have used us. 200+ peer-reviewed medical journals have referenced our original studies. Start now >>>

 

Benadryl

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in allergies. (latest outcomes from 29,405 Benadryl users)

Low blood pressure

Low blood pressure (abnormally low blood pressure) has been reported by people with high blood pressure, pain, multiple sclerosis, osteoporosis, depression. (latest reports from 107,433 Low blood pressure patients)

On May, 4, 2015: 26,443 people reported to have side effects when taking Benadryl. Among them, 1,458 people (5.51%) have Low Blood Pressure.

Trend of Low blood pressure in Benadryl reports

Time on Benadryl when people have Low blood pressure * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Low blood pressure88.30%11.11%0.00%0.00%0.00%0.00%0.58%

Gender of people who have Low blood pressure when taking Benadryl * :

FemaleMale
Low blood pressure56.17%43.83%

Age of people who have Low blood pressure when taking Benadryl * :

0-12-910-1920-2930-3940-4950-5960+
Low blood pressure0.57%2.00%4.86%3.21%6.00%12.79%20.71%49.86%

Severity of Low blood pressure when taking Benadryl ** :

leastmoderateseveremost severe
Low blood pressure28.57%14.29%42.86%14.29%

How people recovered from Low blood pressure ** :

while on the drugafter off the drugnot yet
Low blood pressure33.33%0.00%66.67%

Top conditions involved for these people * :

  1. Pain (76 people, 5.21%)
  2. Hypertension (72 people, 4.94%)
  3. Depression (57 people, 3.91%)
  4. Nausea (56 people, 3.84%)
  5. Non-small cell lung cancer (47 people, 3.22%)

Top co-used drugs for these people * :

  1. Decadron (340 people, 23.32%)
  2. Zofran (266 people, 18.24%)
  3. Tylenol (232 people, 15.91%)
  4. Ativan (225 people, 15.43%)
  5. Aspirin (212 people, 14.54%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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Do you have Low Blood Pressure while taking Benadryl?

 

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Comments from related studies:

  • From this study (7 months ago):

  • on peritoneal dialysis

    Reply

  • From this study (10 months ago):

  • BP ranges 125-130 over 75-87 when getting up prior to meds to 90-50 sometimes in the evening. I am a little stressed and so diphenhydramine helps me sleep along with melatonin. THese are OTC

    Reply

  • From this study (2 years ago):

  • All adverse effects are tolerable and preferential to extreme pain and fatigue which can cause severe MS exacerbation.

    Reply

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