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Review: could Benadryl cause Migraine?

We study 26,362 people who have side effects while taking Benadryl from FDA and social media. Among them, 325 have Migraine. Find out below who they are, when they have Migraine and more.

Stay connected: join a mobile support group for people who take Benadryl and have Migraine >>>

Benadryl

Benadryl (latest outcomes from 29,318 users) has active ingredients of diphenhydramine hydrochloride. It is often used in allergies.

Migraine

Migraine (headache) (latest reports from 171,642 patients) has been reported by people with multiple sclerosis, birth control, depression, osteoporosis, pain.

On Jul, 18, 2014: 26,359 people reported to have side effects when taking Benadryl. Among them, 357 people (1.35%) have Migraine. They amount to 0.21% of all the 172,823 people who have Migraine on eHealthMe.

Trend of Migraine in Benadryl reports

Time on Benadryl when people have Migraine * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Migraine88.89%0.00%0.00%0.00%0.00%0.00%11.11%

Gender of people who have Migraine when taking Benadryl * :

FemaleMale
Migraine90.14%9.86%

Age of people who have Migraine when taking Benadryl * :

0-12-910-1920-2930-3940-4950-5960+
Migraine0.00%1.41%5.28%8.45%18.31%25.70%28.87%11.97%

Severity of Migraine when taking Benadryl ** :

leastmoderateseveremost severe
Migraine0.00%50.00%50.00%0.00%

How people recovered from Migraine ** :

n/a

Top conditions involved for these people * :

  1. Migraine (46 people, 12.89%)
  2. Depression (43 people, 12.04%)
  3. Osteoporosis (33 people, 9.24%)
  4. Pain (33 people, 9.24%)
  5. Hypertension (29 people, 8.12%)

Top co-used drugs for these people * :

  1. Zometa (78 people, 21.85%)
  2. Neurontin (70 people, 19.61%)
  3. Zofran (68 people, 19.05%)
  4. Aspirin (58 people, 16.25%)
  5. Reglan (50 people, 14.01%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Get connected! Join a mobile support group to help out with your experience or learn from others anytime and anywhere:
- group for people who take Benadryl and have Migraine
- group for people who take Benadryl
- group for people who have Migraine

Comments from related studies:

  • From this study (2 days ago):

  • I've always had mood swings and have suffered with depression throughout my life. Recently I started taking Benadryl at night to help with allergies. I found that it helped me sleep better also. I'm not sure if I'm just noticing that I may have a mood disorder that's always been there or if it is caused by the Benadryl requip combo

    Reply

  • From this study (2 weeks ago):

  • My most severe symptoms would be the shortness of breath, muscle weakness and this chronic pain under my left rib that goes around to my back and up to my shoulder blade. Occasionally that pain will go to my left chest, clavicle and jaw. But all of my pain is on the left side. I have degenerative disc disease and spinal stenosis too. Chronic headaches are dizziness are awful and debilitating.

    Reply

  • From this study (2 weeks ago):

  • Frequent migraines, neck and spine pain

    Reply

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On eHealthMe, Benadryl (diphenhydramine hydrochloride) is often used for allergies. Find out below the conditions Benadryl is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Benadryl used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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