Review: could Benadryl cause Migraine?


Summary

Migraine is found among people who take Benadryl, especially for people who are female, 50-59 old , have been taking the drug for < 1 month, also take medication Tylenol, and have Migraine . We study 37,611 people who have side effects while taking Benadryl from FDA and social media. Among them, 448 have Migraine. Find out below who they are, when they have Migraine and more.

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Benadryl

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in hypersensitivity. (latest outcomes from Benadryl 43,259 users)

Migraine

Migraine (headache) has been reported by people with breathing difficulty, pain, drug ineffective, chest pain, fatigue (latest reports from 74,816 Migraine patients).

On Sep, 17, 2016

37,611 people reported to have side effects when taking Benadryl.
Among them, 448 people (1.19%) have Migraine


Number of reports submitted per year:

Could Benadryl cause Migraine?

Time on Benadryl when people have Migraine *:

  • < 1 month: 75.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 18.75 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 6.25 %

Gender of people who have Migraine when taking Benadryl *:

  • female: 91.14 %
  • male: 8.86 %

Age of people who have Migraine when taking Benadryl *:

  • 0-1: 0.0 %
  • 2-9: 1.74 %
  • 10-19: 6.1 %
  • 20-29: 8.14 %
  • 30-39: 20.35 %
  • 40-49: 24.71 %
  • 50-59: 29.36 %
  • 60+: 9.59 %

Severity if Migraine when taking Benadryl **:

  • least: 0.0 %
  • moderate: 33.33 %
  • severe: 33.33 %
  • most severe: 33.33 %

How people recovered from Migraine **:

  • while on drug: 0.0 %
  • after off the drug: 0.0 %
  • not yet: 100 %

Top conditions involved for these people *:

  • Migraine (69 people, 15.40%)
  • Pain (51 people, 11.38%)
  • Multiple Sclerosis (41 people, 9.15%)
  • Depression (40 people, 8.93%)
  • Gastrooesophageal Reflux Disease (37 people, 8.26%)

Top co-used drugs for these people *:

  • Tylenol (89 people, 19.87%)
  • Neurontin (52 people, 11.61%)
  • Flexeril (50 people, 11.16%)
  • Ativan (49 people, 10.94%)
  • Zofran (44 people, 9.82%)

Top other side effects for these people *:

  • Headache (132 people, 29.46%)
  • Nausea (121 people, 27.01%)
  • Vomiting (115 people, 25.67%)
  • Pain (111 people, 24.78%)
  • Dyspnoea (94 people, 20.98%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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