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Review: could Benadryl cause Raynaud's phenomenon?

We study 26,361 people who have side effects while taking Benadryl from FDA and social media. Among them, 29 have Raynaud's phenomenon. Find out below who they are, when they have Raynaud's phenomenon and more.

Stay connected: join a mobile support group for people who take Benadryl and have Raynaud's phenomenon >>>

Benadryl

Benadryl (latest outcomes from 29,318 users) has active ingredients of diphenhydramine hydrochloride. It is often used in allergies.

Raynaud's phenomenon

Raynaud's phenomenon (discoloration of the fingers, toes, and occasionally other areas) (latest reports from 12,421 patients) has been reported by people with osteoporosis, high blood pressure, rheumatoid arthritis, multiple sclerosis, attention deficit hyperactivity disorder.

On Jul, 13, 2014: 26,359 people reported to have side effects when taking Benadryl. Among them, 29 people (0.11%) have Raynaud's Phenomenon. They amount to 0.23% of all the 12,405 people who have Raynaud's Phenomenon on eHealthMe.

Trend of Raynaud's phenomenon in Benadryl reports

Time on Benadryl when people have Raynaud's phenomenon * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Raynaud's phenomenon100.00%0.00%0.00%0.00%0.00%0.00%0.00%

Gender of people who have Raynaud's phenomenon when taking Benadryl * :

FemaleMale
Raynaud's phenomenon93.10%6.90%

Age of people who have Raynaud's phenomenon when taking Benadryl * :

0-12-910-1920-2930-3940-4950-5960+
Raynaud's phenomenon0.00%0.00%0.00%33.33%16.67%0.00%16.67%33.33%

Severity of Raynaud's phenomenon when taking Benadryl ** :

n/a

How people recovered from Raynaud's phenomenon ** :

n/a

Top conditions involved for these people * :

  1. Osteoporosis (15 people, 51.72%)
  2. Blood pressure (4 people, 13.79%)
  3. Rheumatoid arthritis (4 people, 13.79%)
  4. Premenstrual syndrome (2 people, 6.90%)
  5. Acne (2 people, 6.90%)

Top co-used drugs for these people * :

  1. Prevacid (18 people, 62.07%)
  2. Demerol (16 people, 55.17%)
  3. Zantac (16 people, 55.17%)
  4. Diazepam (15 people, 51.72%)
  5. Amoxicillin (15 people, 51.72%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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Comments from related studies:

  • From this study (1 week ago):

  • I have been having charlie horses for about a month. I also have muscle twitching that started in one leg and within two weeks it has spread to my entire body. my blood work came back normal.

    Reply

  • From this study (1 week ago):

  • 27 L knee operations, three massive L knee infections resulting in a third and final arthoplasty revision. Extensive soft tissue damage resulting in perminante subqutanious sutuers and locking full leg brace, also perminante.

    Daily swelling in the knee joint (4 to 6 cm daily). Constant pain as well as additional pain when walking.

    Reply

  • From this study (2 weeks ago):

  • Itching in extremeties with no rash apparent. Eyes watery and burning. Twitching is in left eyelid. Itching started 8 days ago. Lotion does not help much. Diphenhydramine does not help much.

    Reply

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On eHealthMe, Benadryl (diphenhydramine hydrochloride) is often used for allergies. Find out below the conditions Benadryl is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Benadryl used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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