Review: could Benadryl cause Restless legs (Restless Leg Syndrome)?
Summary: Restless legs is found among people who take Benadryl, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take medication Coumadin, and have Gastrooesophageal reflux disease. We study 26,443 people who have side effects while taking Benadryl from FDA and social media. Among them, 81 have Restless legs. Find out below who they are, when they have Restless legs and more.
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Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in allergies. (latest outcomes from 29,405 Benadryl users)
Restless legs (a powerful urge to move your legs) has been reported by people with osteoporosis, depression, pain, high blood pressure, stress and anxiety. (latest reports from 17,510 Restless legs patients)
On May, 1, 2015: 26,443 people reported to have side effects when taking Benadryl. Among them, 80 people (0.30%) have Restless Legs.
Time on Benadryl when people have Restless legs * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
|Restless legs||70.00%||0.00%||0.00%||10.00%||10.00%||0.00%||10.00% |
Gender of people who have Restless legs when taking Benadryl * :
|Restless legs||70.13%||29.87% |
Age of people who have Restless legs when taking Benadryl * :
|Restless legs||0.00%||0.00%||0.00%||4.62%||1.54%||23.08%||18.46%||52.31% |
Severity of Restless legs when taking Benadryl ** :
|least||moderate||severe||most severe |
|Restless legs||0.00%||0.00%||66.67%||33.33% |
How people recovered from Restless legs ** :
Top conditions involved for these people * :
- Gastrooesophageal reflux disease (11 people, 13.75%)
- Crohn's disease (8 people, 10.00%)
- Restless legs syndrome (5 people, 6.25%)
- Diabetes mellitus (5 people, 6.25%)
- Impaired gastric emptying (4 people, 5.00%)
Top co-used drugs for these people * :
- Coumadin (28 people, 35.00%)
- Pepcid (25 people, 31.25%)
- Prilosec (24 people, 30.00%)
- Zofran (24 people, 30.00%)
- Levaquin (22 people, 27.50%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
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Comments from related studies:
From this study (2 weeks ago):
I have personality disorder, bipolar,anxiety,insomnia. been off antipsychotics for 9 months
From this study (2 years ago):
I seem to have more RLS when combining promethazine, methocarbomal, and/or diphenhydramine. Is this a problem for blood clots? About to start Seasonale and all birth control pills are warning about blood clots.
deerfisherman on Dec, 23, 2012:
Benadryl is a trigger for Restless Leg s. do not take it or your legs will jump.
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