Benadryl and Serotonin syndrome - from FDA reports


Summary

Serotonin syndrome is found among people who take Benadryl, especially for people who are female, 50-59 old also take medication Zofran, and have Depression. This review analyzes which people have Serotonin syndrome with Benadryl. It is created by eHealthMe based on reports of 43,578 people who have side effects when taking Benadryl from FDA, and is updated regularly.

What to expect?

If you take Benadryl and have Serotonin syndrome, find out what symptoms you could have in 1 year or longer.

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On May, 11, 2017

43,578 people reported to have side effects when taking Benadryl.
Among them, 36 people (0.08%) have Serotonin Syndrome


Number of reports submitted per year:

Could Benadryl cause Serotonin syndrome?

Gender of people who have Serotonin Syndrome when taking Benadryl *:

  • female: 80.56 %
  • male: 19.44 %

Age of people who have Serotonin Syndrome when taking Benadryl *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 6.45 %
  • 20-29: 0.0 %
  • 30-39: 12.9 %
  • 40-49: 12.9 %
  • 50-59: 45.16 %
  • 60+: 22.58 %

Top conditions involved for these people *:

  • Depression (22 people, 61.11%)
  • Pain (12 people, 33.33%)
  • Stress And Anxiety (9 people, 25.00%)
  • Procedural Pain (7 people, 19.44%)
  • Nausea (7 people, 19.44%)

Top co-used drugs for these people *:

  • Zofran (11 people, 30.56%)
  • Wellbutrin (10 people, 27.78%)
  • Prozac (10 people, 27.78%)
  • Valium (9 people, 25.00%)
  • Promethazine (9 people, 25.00%)

Top other side effects for these people *:

  • Nausea (10 people, 27.78%)
  • Agitation (9 people, 25.00%)
  • Nausea And Vomiting (8 people, 22.22%)
  • Feeling Abnormal (8 people, 22.22%)
  • Fall (8 people, 22.22%)

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Serotonin syndrome when taking Benadryl?

Benadryl

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in allergies. (latest outcomes from Benadryl 47,702 users)

Serotonin Syndrome

Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time) has been reported by people with depression, pain, stress and anxiety, major depression, insomnia (latest reports from 10,171 Serotonin syndrome patients).

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Drugs that are associated with Serotonin syndrome

Serotonin syndrome

Could your condition cause Serotonin syndrome

Serotonin syndrome

Related studies

What would happen?

Forecast new side effects and undetected conditions when you take Benadryl and have Serotonin syndrome.

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