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Home > Benadryl > Withdrawal syndrome > Benadryl and Withdrawal syndrome

Review: could Benadryl cause Withdrawal syndrome?

Summary: Withdrawal syndrome is found among people who take Benadryl, especially for people who are female, 40-49 old, have been taking the drug for < 1 month, also take medication Xanax, and have Hypertension.

We study 26,402 people who have side effects while taking Benadryl from FDA and social media. Among them, 47 have Withdrawal syndrome. Find out below who they are, when they have Withdrawal syndrome and more.

You are not alone: join a mobile support group for people who take Benadryl and have Withdrawal syndrome >>>

Benadryl

Benadryl (latest outcomes from 29,359 users) has active ingredients of diphenhydramine hydrochloride. It is often used in allergies.

Trend of benadryl reports

Withdrawal syndrome

Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance) (latest reports from 9,186 patients) has been reported by people with depression, pain, stress and anxiety, muscle spasticity, back pain.

Trend of Withdrawal syndrome reports

On Nov, 13, 2014: 26,394 people reported to have side effects when taking Benadryl. Among them, 47 people (0.18%) have Withdrawal Syndrome.

Trend of Withdrawal syndrome in Benadryl reports

Time on Benadryl when people have Withdrawal syndrome * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Withdrawal syndrome50.00%0.00%33.33%0.00%0.00%0.00%16.67%

Gender of people who have Withdrawal syndrome when taking Benadryl * :

FemaleMale
Withdrawal syndrome62.50%37.50%

Age of people who have Withdrawal syndrome when taking Benadryl * :

0-12-910-1920-2930-3940-4950-5960+
Withdrawal syndrome0.00%21.43%0.00%0.00%10.71%35.71%10.71%21.43%

Severity of Withdrawal syndrome when taking Benadryl ** :

leastmoderateseveremost severe
Withdrawal syndrome0.00%0.00%0.00%100.00%

How people recovered from Withdrawal syndrome ** :

while on the drugafter off the drugnot yet
Withdrawal syndrome0.00%100.00%0.00%

Top conditions involved for these people * :

  1. Hypertension (20 people, 42.55%)
  2. Depression (19 people, 40.43%)
  3. Breast cancer (16 people, 34.04%)
  4. Metastases to bone (16 people, 34.04%)
  5. Diabetes mellitus (16 people, 34.04%)

Top co-used drugs for these people * :

  1. Xanax (21 people, 44.68%)
  2. Reglan (20 people, 42.55%)
  3. Ibuprofen (18 people, 38.30%)
  4. Hydrochlorothiazide (17 people, 36.17%)
  5. Promethazine (17 people, 36.17%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Withdrawal Syndrome while taking Benadryl?

You are not alone! Join a mobile support group:
- support group for people who take Benadryl and have Withdrawal Syndrome
- support group for people who take Benadryl
- support group for people who have Withdrawal Syndrome

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You may be interested at these reviews (Write a review):

  • Dyphenhydramine and headaches horrible going one almost 24 hours a day for 4 weeks and cant get them to stop, now looking for cause . think its the dyphenhydramine im taking to help me sleep .
    (Posted by a 63 year old woman who has Headaches, and takes Diphenhydramine Hydrochloride)
    have been taking 3 dyphenhydramine for some time to help me sleep , just in last few weeks began having severe headache almost all the time.. cant get it to go away. just found out it can cause headache and am going to lower my intake to one per night and see if my headaches get better. am taking mi ...

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    (Posted by a 54 year old man who has Nightmare, Hard Time Sleeping, and takes Benadryl)
    After 5 nights without sleep and not having past bad dreams, the last 2 night's taking walfrin sub, for benadryl has terrified THE WORST OF WORST dream in my 55 years. Peaceful start of a dream then seeing myself or family,friends get slottard.crazy thing is I don't watch scary movies or the news. I ...

  • Benadryl completed suicide 50 year old
    (Posted by a 50 year old woman who has Completed Suicide, and takes Alcohol, Methenamine Hippurate, Xanax, Benadryl)
    My mother comitted suicide by taking a bottle of Benadryl. She also had been drinking, she had taken xanax and drank beer, she also took 300 Benadryl pills and started having seizures and went to the hospital was brain dead and her heart stopped the next morning.

  • Lorazepam nearly killed me during cancer treatment
    (Posted by a 66 year old woman who has Insomnia, Bowel Movement Irregularity, Withdrawal Syndrome, and takes Wellbutrin Sr, Prozac, Lorazepam)
    Day 31 of cold turkey and I want to die. It is a roller coaster from body tics and sweats to rage and crying in one day. I felt so good the 4h day of c/t. It was like before my cancer diagnosis. My bowels are better off Lorazepam. I threw up during bowel movements from the pain. Off Lorazepam first ...

  • Had nms in 2005, will trileptal increase chance of recurrence?
    (Posted by a 62 year old woman who has Narcolepsy, Prinzmetal's Angina , Antiphospholipid Syndrome, High Blood Pressure, Obsessive-compulsive Personality Disorder, Cyclic Vomiting Syndrome, Migraine With Aura, Herniated Intervertebral Disk, Osteoarthritis, Fibromyalgia, Rheumatoid Arthritis, Diabetes Mellitus Insulin-dependent, Bipolar I Disorder, and takes Benadryl, Baclofen, Plaquenil, Nitro-bid, Maxalt-mlt, Imitrex, Zofran Odt, Ms Contin, Clonidine, Amlodipine Besylate, Novolog Flexpen, Levemir Flexpen, Halcion, Valium, Primidone, Neurontin, Trileptal)
    In 2005 I had NMS, which was not detected by my drs for 4 months. I'd been on Lexapro & Seroquel for 2 yrs, but was weaned from Lexapro & placed on Lamictal 3/05. Began getting low-grade fevers, which I was told were not caused by the Lamictal. I quit taking it anyway, fevers (along with uncontrolla ...

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