Review: could Benadryl cause Withdrawal syndrome?
Summary: Withdrawal syndrome is found among people who take Benadryl, especially for people who are female, 40-49 old, have been taking the drug for < 1 month, also take medication Xanax, and have High blood pressure. We study 26,443 people who have side effects while taking Benadryl from FDA and social media. Among them, 47 have Withdrawal syndrome. Find out below who they are, when they have Withdrawal syndrome and more.
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Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in allergies. (latest outcomes from 29,405 Benadryl users)
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance) has been reported by people with depression, pain, stress and anxiety, muscle spasticity, back pain. (latest reports from 9,229 Withdrawal syndrome patients)
On May, 16, 2015: 26,443 people reported to have side effects when taking Benadryl. Among them, 47 people (0.18%) have Withdrawal Syndrome.
Time on Benadryl when people have Withdrawal syndrome * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
|Withdrawal syndrome||50.00%||0.00%||33.33%||0.00%||0.00%||0.00%||16.67% |
Gender of people who have Withdrawal syndrome when taking Benadryl * :
|Withdrawal syndrome||62.50%||37.50% |
Age of people who have Withdrawal syndrome when taking Benadryl * :
|Withdrawal syndrome||0.00%||21.43%||0.00%||0.00%||10.71%||35.71%||10.71%||21.43% |
Severity of Withdrawal syndrome when taking Benadryl ** :
|least||moderate||severe||most severe |
|Withdrawal syndrome||0.00%||0.00%||0.00%||100.00% |
How people recovered from Withdrawal syndrome ** :
|while on the drug||after off the drug||not yet |
|Withdrawal syndrome||0.00%||100.00%||0.00% |
Top conditions involved for these people * :
- Hypertension (20 people, 42.55%)
- Depression (19 people, 40.43%)
- Breast cancer (16 people, 34.04%)
- Metastases to bone (16 people, 34.04%)
- Diabetes mellitus (16 people, 34.04%)
Top co-used drugs for these people * :
- Xanax (21 people, 44.68%)
- Reglan (20 people, 42.55%)
- Ibuprofen (18 people, 38.30%)
- Hydrochlorothiazide (17 people, 36.17%)
- Promethazine (17 people, 36.17%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
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Do you have Withdrawal Syndrome while taking Benadryl?
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Comments from related studies:
From this study (3 years ago):
The length of time I've struggled with sleep disorders has resulted in higher than normal Benadryl usage, but I wake up every day (after only a few hours of sleep) with my ears feeling plugged now. Benadryl is the only thing I have found to relieve the pressure, increasing my usage of the drug even more.
NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.
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