Review: could Benadryl cause Withdrawal syndrome?
We study 26,361 people who have side effects while taking Benadryl from FDA and social media. Among them, 47 have Withdrawal syndrome. Find out below who they are, when they have Withdrawal syndrome and more.
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Benadryl (latest outcomes from 29,318 users) has active ingredients of diphenhydramine hydrochloride. It is often used in allergies.
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance) (latest reports from 56,284 patients) has been reported by people with depression, pain, stress and anxiety, muscle spasticity, back pain.
On Jul, 12, 2014: 26,359 people reported to have side effects when taking Benadryl. Among them, 47 people (0.18%) have Withdrawal Syndrome. They amount to 0.08% of all the 55,980 people who have Withdrawal Syndrome on eHealthMe.
Time on Benadryl when people have Withdrawal syndrome * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
|Withdrawal syndrome||50.00%||0.00%||33.33%||0.00%||0.00%||0.00%||16.67% |
Gender of people who have Withdrawal syndrome when taking Benadryl * :
|Withdrawal syndrome||62.50%||37.50% |
Age of people who have Withdrawal syndrome when taking Benadryl * :
|Withdrawal syndrome||0.00%||21.43%||0.00%||0.00%||10.71%||35.71%||10.71%||21.43% |
Severity of Withdrawal syndrome when taking Benadryl ** :
|least||moderate||severe||most severe |
|Withdrawal syndrome||0.00%||0.00%||0.00%||100.00% |
How people recovered from Withdrawal syndrome ** :
|while on the drug||after off the drug||not yet |
|Withdrawal syndrome||0.00%||100.00%||0.00% |
Top conditions involved for these people * :
- Hypertension (20 people, 42.55%)
- Depression (19 people, 40.43%)
- Breast cancer (16 people, 34.04%)
- Metastases to bone (16 people, 34.04%)
- Diabetes mellitus (16 people, 34.04%)
Top co-used drugs for these people * :
- Xanax (21 people, 44.68%)
- Reglan (20 people, 42.55%)
- Ibuprofen (18 people, 38.30%)
- Hydrochlorothiazide (17 people, 36.17%)
- Promethazine (17 people, 36.17%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
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Get connected! Join a mobile support group:
- group for people who take Benadryl and have Withdrawal Syndrome
- group for people who take Benadryl
- group for people who have Withdrawal Syndrome
Comments from related studies:
From this study (2 years ago):
The length of time I've struggled with sleep disorders has resulted in higher than normal Benadryl usage, but I wake up every day (after only a few hours of sleep) with my ears feeling plugged now. Benadryl is the only thing I have found to relieve the pressure, increasing my usage of the drug even more.
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On eHealthMe, Benadryl (diphenhydramine hydrochloride) is often used for allergies. Find out below the conditions Benadryl is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.
What is Benadryl used for and how effective is it:
Other drugs that are used to treat the same conditions:
Could it be a symptom from a condition:
Drugs in real world that are associated with:
Could your condition cause it?
NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.
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