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Review: could Botox cause Stevens-johnson syndrome (Erythema multiforme)?

Summary: Stevens-johnson syndrome is found among people who take Botox, especially for people who are male, 60+ old, have been taking the drug for < 1 month, also take medication Botox purified neurotoxin complex, and have Torticollis.

We study 12,801 people who have side effects while taking Botox from FDA and social media. Among them, 6 have Stevens-johnson syndrome. Find out below who they are, when they have Stevens-johnson syndrome and more.

You are not alone: join a mobile support group for people who take Botox and have Stevens-johnson syndrome >>>

 

 

 

 

Botox

Botox has active ingredients of botulinum toxin type a. It is often used in aging changes in skin. (latest outcomes from 12,985 Botox users)

Stevens-johnson syndrome

Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe) has been reported by people with convulsion, high blood pressure, epilepsy, ill-defined disorder, bipolar disorder. (latest reports from 27,933 Stevens-johnson syndrome patients)

On Jan, 30, 2015: 12,800 people reported to have side effects when taking Botox. Among them, 6 people (0.05%) have Stevens Johnson Syndrome.

Trend of Stevens johnson syndrome in Botox reports

Time on Botox when people have Stevens johnson syndrome * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Stevens johnson syndrome80.00%0.00%0.00%20.00%0.00%0.00%0.00%

Gender of people who have Stevens johnson syndrome when taking Botox * :

FemaleMale
Stevens johnson syndrome14.29%85.71%

Age of people who have Stevens johnson syndrome when taking Botox * :

0-12-910-1920-2930-3940-4950-5960+
Stevens johnson syndrome0.00%0.00%0.00%0.00%0.00%0.00%0.00%100.00%

Severity of Stevens johnson syndrome when taking Botox ** :

n/a

How people recovered from Stevens johnson syndrome ** :

n/a

Top conditions involved for these people * :

  1. Torticollis (3 people, 50.00%)
  2. Myokymia (1 people, 16.67%)
  3. Muscle spasticity (1 people, 16.67%)

Top co-used drugs for these people * :

  1. Botox purified neurotoxin complex (2 people, 33.33%)
  2. Nivadil (1 people, 16.67%)
  3. Trental (1 people, 16.67%)
  4. Artane (1 people, 16.67%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Stevens-johnson Syndrome while taking Botox?

You are not alone! Join a mobile support group:
- support group for people who take Botox and have Stevens-johnson Syndrome
- support group for people who take Botox
- support group for people who have Stevens-johnson Syndrome

Drugs in real world that are associated with:

Could your condition cause:

Can you answer these questions (Ask a question):

  • Do botox injections for migraines possibly cause loss of effectiveness of novacaines numbing ability ?
    I received the Botox injections for migraine prevention and then within the following couple of days, I had some dental work done for a new crown. This is the first time in my life that the dentist could not effectively numb my gums . It took about 8 to 10 injections over an hour before I was finally feeling numb. My question is : does the Botox cause this problem, ie, is the botox contraindicated for Novocain ? I look forward to an educated response. Thanks someone !Snutch
  • Can you have botox injections in face when taking votrient
    I would like to know if anyone taking Votrient has had cosmetic Botox injections. If so have you had any reaction?
  • Has anyone experienced getting perioral dermatitis after botox injections?
    Approx. 1 year ago perioral dermatitis on my face occured.
    My skin was always very nice and quite resistant.
    Never suffered from eczema, acne or anything like that.
    When I tried to figure out the reason, the only thing, which comes on my mind is, I had had botox injections about month before my dermatitis started. Has anyone experienced sth similar? Thanks Adela
  • Can botox for migraines cause sleep apnea?
    I had botox injections for non-stop migraines on Sept, 3rd. Last night(3 weeks later) my throat closed off completely while sleeping at least 3 times. This is the first round of botox, but my face swelled and I had itching sensations inside my nose and chest happened approx. 2 hours after the injections. It feels like there is a flap in my throat that is closing off my air and I have to cough and gasp to get air. Anybody else have this problem?
    The doctor only injected the side of my head that the migraines are occurring, he put 2 or 3 injections in the back of my head, close to the bottom of head.
    The doctor thinks it is unrelated to the injections, but why is it happening now and not any time before the injections?
  • Can i connect by email with other patients that have hypoglycemia and stevens-johnson syndrome? (1 answer)
    I have had hypoglycemia since childhood, and I have managed it easily until just this weekend. I got S-J two years ago from Bactrim. As I have healed from S-J very slowly and painfully, I was exercising hard, and working hard and slipped a little on not eating enough protein. I started dropping into sugar blackouts and it scared the crap out of me! Still working at being able to eat enough to straighten out low sugar levels. Any suggestions helpful, Thanks, Leann

More questions for: Botox, Stevens-johnson syndrome

You may be interested at these reviews (Write a review):

  • Botox & gi bleed 5 weeks after
    had Botox for my stroke in my leg and ankle and 5 wks. later had a severe GI Bleed.This happened twice.
  • Aleve and erythema multiforme
    I started exercising (walking outside)and due to sore knees I started taking Aleve. Within days I developed blisters on my chest, back, face, and inside my mouth. Mouth blisters were severe enough that I could only consume liquids. After 7-10 days the blisters scabbed over. This occurred three times within a two month period, the last time I had blisters around my eyes with physician concern of eye involvement but it did not happen. During the second round I went to a dermatologist and he determined that I had Erythema Multiforme and the cause was either a strep throat or Aleve. A second opinion determined it was Aleve partly because strep throat is not normally associated with EM. I have stopped taking Aleve and am EM free for 15 months.
  • Botox and dry eye pain
    I have severe dry eye, very painful at night, with gritty feeling 75% of the day. Drops such as gels, liquids, were used (Muro 128, genteal). Then switched to preservative free drops which have helped by 90%.

    There is research about the injection of botox into crows feet and causing dry eye. This may be reversible and I am waiting to see whether the problem subsides and my condition returns to normal. I also have the feeling that my lids have slackened and are not fitting together closely. This is another effect of botox around the eye socket, in crows feet and centrally under the lower lid.
  • Stevens johnson syndrome- flagyl for h.pylori (1 response)
    Diagnosed with h.pylori with positive blood work and breath-test.

    Started 7 day course of Amoxycillin and Flagyl .

    On day 7, developed symptoms- large red 2inch hives on legs, extreme frontal headache , pressure behind eyes, pink eye, pain in eyes, sore throat, very slight fever and body ache. Last dose of Flagyl and Amoxycillin was not taken. Symptoms disappeared after 48 hours.



    Abdominal pain returned after month.



    Started 2nd treatment to eradicate h.pylori. After 3rd dose of Tetracyline and Flagyl, developed same Stevens Johnsons symptoms --large hives, low grade fever, eye pain and redness, extreme headache, pressure behind eyes, sore throat and feeling of impending doom. Stopped taking antibiotics, symptoms disappeared in 48 hours.



    Evaluation- I am extremely allergic to Flagyl. I required allergy testing to determine which antibiotics I can safely take in the future.

More reviews for: Botox, Stevens-johnson syndrome

Comments from related studies:

  • From this study (2 weeks ago):

  • been receiving botox injections for crows feet for 10 years. After last injection 4 months ago began having rash and redness of upper eyelids. Seen by MD was told eczema. Keeps returning .

    Reply

  • From this study (2 weeks ago):

  • Had Botox for the first time July 2012. Noticed triangular dents 3 days later (they have never disappeared) face appears flat (all volume gone). Couldnt raise my eyebrows for at least 9 months, had to manually lift my brow to put mascara on. Cheek droop (but recovered mostly from that now) eyes looked sunken for about 1.5 yrs, (right eye still looks sunken) hollow caved in temple area (guessing that's from having my forehead injected) had dry eyes for roughly a 1yr, and strangely I still get shooting pains every now and then around my eyes. My eyes look like an old ladies eyes now, they look empty and hollow, skin looks like orange peel (Lower lids). Can feel my face pulling when I make certain expressions (like its so tight in some areas) left side of face is getting better, right side is still very droopy, skin laxity, pulls in funny directions when making expressions.

    Reply

  • From this study (4 weeks ago):

  • Basically at death's door!

    Reply

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