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Review: could Botox cause Stevens-johnson syndrome?

Summary: Stevens-johnson syndrome could be caused by Botox, especially for people who are male, 60+ old, have been taking the drug for < 1 month, also take Botox purified neurotoxin complex, and have Torticollis.

We study 12,776 people who have side effects while taking Botox from FDA and social media. Among them, 6 have Stevens-johnson syndrome. Find out below who they are, when they have Stevens-johnson syndrome and more.

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Botox

Botox (latest outcomes from 12,957 users) has active ingredients of botulinum toxin type a. It is often used in aging changes in skin.

Stevens-johnson syndrome

Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe) (latest reports from 134,811 patients) has been reported by people with convulsion, high blood pressure, epilepsy, ill-defined disorder, fever.

On Apr, 10, 2014: 12,762 people reported to have side effects when taking Botox. Among them, 6 people (0.05%) have Stevens-johnson Syndrome. They amount to 0.00% of all the 134,656 people who have Stevens-johnson Syndrome on eHealthMe.

Trend of Stevens-johnson syndrome in Botox reports

Time on Botox when people have Stevens-johnson syndrome * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Stevens-johnson syndrome80.00%0.00%0.00%20.00%0.00%0.00%0.00%

Gender of people who have Stevens-johnson syndrome when taking Botox * :

FemaleMale
Stevens-johnson syndrome14.29%85.71%

Age of people who have Stevens-johnson syndrome when taking Botox * :

0-12-910-1920-2930-3940-4950-5960+
Stevens-johnson syndrome0.00%0.00%0.00%0.00%0.00%0.00%0.00%100.00%

Severity of Stevens-johnson syndrome when taking Botox ** :

n/a

How people recovered from Stevens-johnson syndrome ** :

n/a

Top conditions involved for these people * :

  1. Torticollis (3 people, 50.00%)
  2. Myokymia (1 people, 16.67%)
  3. Muscle spasticity (1 people, 16.67%)

Top co-used drugs for these people * :

  1. Botox purified neurotoxin complex (2 people, 33.33%)
  2. Nivadil (1 people, 16.67%)
  3. Trental (1 people, 16.67%)
  4. Artane (1 people, 16.67%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Botox, Stevens-johnson syndrome

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On eHealthMe, Botox (botulinum toxin type a) is often used for aging changes in skin. Find out below the conditions Botox is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Botox used for and how effective is it:

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Comments from related studies:

  • From this study (2 weeks ago):

  • I began to have muscle and joint pain and burning in muscles 1 month after my botox injection. I have a positive RA factor. It is now 5 months after botox injection and I am in severe pain.

    Reply

  • From this study (4 weeks ago):

  • I'm currently 19 years old, and I've been on generic Zoloft 50 mg (AKA sertraline) since I was 13 due to anxiety attacks after the death of my sister. At first it didn't help much, but I kept with it to see if it would eventually help me. I started having bad anxiety again at 15 and was bumped up to 150 mg. After about a month the raised amount I was prescribed made me feel like I was going crazy. I couldn't think straight, sleep right, I was having problems with school work, and I was constantly fighting with my family, so I tapered myself back down to 100, and then back down to 50. In the last year I've had no panic attacks, but recently my anxiety has returned and I feel like it's worsening again. I can't even drink coffee without my heart pounding, causing me to feel anxious. Even getting too little sleep makes me feel anxious. I can be at work and feel anxious for no reason. I can be at work and blink and feel like I'm dreaming, and I'll get anxious for no reason at all. I grind my teeth in my sleep now, I have trouble falling asleep, trouble waking up. I just wanted to get off Zoloft, so now I'm down to a fourth of a pill every two days, but I want to be off of it for good and I honestly can't get past not taking it for a third day because my withdrawals are so severe. The electro jolt feeling makes it literally impossible to focus on anything or stand for a long period of time. Two days ago I had hives from what I thought was an allergic reaction, but the next day I went to the doctor because the itching was so severe and still there, and the urgent care facility diagnosed me with erythema multiforme minor, gave no tests, and prescribed me prednisone and a corticosteroid ointment to use and told me to have a nice day. I'm just wondering if the sertraline is causing it or if I'm actually sick with something else.

    Reply

  • From this study (1 month ago):

  • Nuvigil use followed by rash followed by massive sore. Have seen that penicillin allergy should not be treated with Nuvigil. Nuvigil works for intended use but fear SJS interacion. Please advise.

    Reply

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