Review: could Bupropion Hydrochloride cause Irritability?


Irritability is found among people who take Bupropion Hydrochloride, especially for people who are female, 40-49 old , have been taking the drug for < 1 month, also take medication Clonazepam, and have Depression . We study 6,425 people who have side effects while taking Bupropion hydrochloride from FDA and social media. Among them, 99 have Irritability. Find out below who they are, when they have Irritability and more.

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Bupropion Hydrochloride

Bupropion hydrochloride has active ingredients of bupropion hydrochloride. It is often used in depression. (latest outcomes from Bupropion hydrochloride 7,340 users)


Irritability has been reported by people with fever, rashes, drug ineffective, weight increased, insomnia (latest reports from 26,088 Irritability patients).

On Aug, 22, 2016

6,425 people reported to have side effects when taking Bupropion Hydrochloride.
Among them, 99 people (1.54%) have Irritability

Number of reports submitted per year:

Could Bupropion hydrochloride cause Irritability?

Time on Bupropion Hydrochloride when people have Irritability *:

  • < 1 month: 32.26 %
  • 1 - 6 months: 25.81 %
  • 6 - 12 months: 6.45 %
  • 1 - 2 years: 9.68 %
  • 2 - 5 years: 9.68 %
  • 5 - 10 years: 9.68 %
  • 10+ years: 6.45 %

Gender of people who have Irritability when taking Bupropion Hydrochloride *:

  • female: 73.2 %
  • male: 26.8 %

Age of people who have Irritability when taking Bupropion Hydrochloride *:

  • 0-1: 1.23 %
  • 2-9: 0.0 %
  • 10-19: 4.94 %
  • 20-29: 4.94 %
  • 30-39: 23.46 %
  • 40-49: 35.8 %
  • 50-59: 22.22 %
  • 60+: 7.41 %

Severity if Irritability when taking Bupropion Hydrochloride **:

  • least: 7.69 %
  • moderate: 53.85 %
  • severe: 30.77 %
  • most severe: 7.69 %

How people recovered from Irritability **:

  • while on drug: 0.0 %
  • after off the drug: 0.0 %
  • not yet: 100 %

Top conditions involved for these people *:

  • Depression (47 people)
  • Bipolar Disorder (14 people)
  • Hypothyroidism (8 people)
  • Anxiety (7 people)
  • Smoking Cessation Therapy (5 people)

Top co-used drugs for these people *:

  • Clonazepam (17 people)
  • Neurontin (9 people)
  • Paxil (8 people)
  • Lithium Carbonate (8 people)
  • Lamotrigine (8 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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