Review: could Carbidopa and levodopa cause Tardive dyskinesia?
Summary: Tardive dyskinesia is found among people who take Carbidopa and levodopa, especially for people who are female, 60+ old, also take medication Metoclopramide, and have Gastrooesophageal reflux disease.
We study 2,274 people who have side effects while taking Carbidopa and levodopa from FDA and social media. Among them, 15 have Tardive dyskinesia. Find out below who they are, when they have Tardive dyskinesia and more.
You are not alone: join a mobile support group for people who take Carbidopa and levodopa and have Tardive dyskinesia >>>
Carbidopa and levodopa
Carbidopa and levodopa has active ingredients of carbidopa; levodopa. It is often used in parkinson's disease. (latest outcomes from 2,478 Carbidopa and levodopa users)
Tardive dyskinesia (a disorder that involves involuntary movements) has been reported by people with indigestion, abdominal distension, bipolar disorder, depression, gastrointestinal disorder. (latest reports from 23,256 Tardive dyskinesia patients)
On Jan, 28, 2015: 2,274 people reported to have side effects when taking Carbidopa and levodopa. Among them, 15 people (0.66%) have Tardive Dyskinesia.
Time on Carbidopa and levodopa when people have Tardive dyskinesia * :
Gender of people who have Tardive dyskinesia when taking Carbidopa and levodopa * :
|Tardive dyskinesia||53.33%||46.67% |
Age of people who have Tardive dyskinesia when taking Carbidopa and levodopa * :
|Tardive dyskinesia||0.00%||12.50%||0.00%||0.00%||0.00%||0.00%||12.50%||75.00% |
Severity of Tardive dyskinesia when taking Carbidopa and levodopa ** :
How people recovered from Tardive dyskinesia ** :
Top conditions involved for these people * :
- Gastrooesophageal reflux disease (5 people, 33.33%)
- Restless legs syndrome (2 people, 13.33%)
- Gastric disorder (1 people, 6.67%)
- Impaired gastric emptying (1 people, 6.67%)
- Oesophageal hypomotility (1 people, 6.67%)
Top co-used drugs for these people * :
- Metoclopramide (9 people, 60.00%)
- Amoxicillin (8 people, 53.33%)
- Aspirin (7 people, 46.67%)
- Xanax (6 people, 40.00%)
- Lexapro (6 people, 40.00%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
Do you have Tardive Dyskinesia while taking Carbidopa And Levodopa?
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Drugs in real world that are associated with:
Could your condition cause:
Can you answer these questions (Ask a question):
- Can prolia cause parkinson?
Parkinson appeared to my mother after few time since 1st. Injection of Prolia, 2 years ago had the 2d. These are the patologies she has, and the drugs she takes:
- Bronchial asthma. - Hiatus hernia. Hashimoto -tiroiditis with hypo- and hyperthyroidism. - Bronchiectasis. - Nasal polyps. - Anxiety. - Neoplasia sigma (2012). I.Q. -- Prolapse uterino- - Cystocele grade II-III (2012). I.Q. - Fibroadenoma.
- Sinemet plus
- Calcium sandoz
- What are effects of psychiatric medications on milk thistle?
I have schizophrenia and I take all the modern drugs to combat - including haldol, risperidone, and generic seroquel. I was just wondering because of a bloated stomach would milk thistle interact with these medications. I just heard it was good for you. 'educated theory', non-publicized by me, both 'health professionals'. Don't feel afraid to tell me the truth.
- How often is parkinson's disease confused with chronic lyme diseasse?
Back in the early 1950s I had the joy and privilege of spending a couple of summers on Cape Cod. As a kid, a lot of that time was spent playing in the grove of poplar trees and bramble behind the house. I clearly remember numerous buried tics, some of which resulted in a circular ring around the tic sites, some with a rash.
A year later some strange things began: high fever, life-long right-side tendency for tonsillitis, persistent 'mononucleosis', poor memory, low energy, and migraines which eventually became the scourge of my adult life. All that hidden under a blanket of high emotional stress caused by life-altering changes in the family.
2010: diagnosed with well developed Parkinson's Disease (PD).
- I have tried several meds for my rls. first i tried mirapex , then gabapentin and now on sinemet
Have tried ropiranole type drugs, Mirapex, went to gabapentin, now on Sinemet Cr. Feeling depressed, gaining weight, and not getting relief thru the night. Take trazodone to finally get sleep. Worried about side effects of Sinemet CR 25/100 need to take 2 or 3 at night to get relief. Also taking iron supplement. Anybody else have suggestions?
- I have night episodes of binge eating without hunger (1 answer)
I have Parkinson Disease diagnosed 4 years ago. It seems to be a slow developing PD since my symptoms have increased very little or nothing in all these years. I have a serious condition of insomnia, I get asleep very soon but awake many times during the night (6 or 7 times), I have been Rx several drugs for this without success (clonazepam, midazolam, etc) Now I am taking quetiapine 25 mg, which seems to be working but anyway I wakeup a couple of times during the night and then I start eating without any hunger, compulsively. I am gaining weight and dont know what to do orwhat is the cause of this. Please any aadvice would be appreciated.
More questions for: Carbidopa and levodopa, Tardive dyskinesia
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I have always been hypersensitive to drugs. I have multiple allergies which have in some cases caused anaphylaxis. I developed Tardive Dyskinesia after being on Geodone for five days. (stopped geodon immediately after manifestation of symptoms) The symptoms began on the third day. I have managed to keep the Tardive Dyskinesia under control or to a few ticks finding my triggers and avoiding them. Like Caffeine, stress, and anxiety. I also had physical therapy and joined a gym. I also take an herbal supplement Relax and Sleep (4 yrs now) which helps a great deal. Recently, I developed shingles. The pain was unbearable and for some reason it triggered or aggravated Tardive Dyskinesia. I've been having inner tremors ever since and have had two bouts of Tardive Dyskinesia that borders on violent. I look like I'm having a seizure or Parkinsons. I always feel it coming on before it strikes. My chest muscles tighten and my arms and body are tense but I'm constantly moving. I can't speak and have difficulty walking when it occurs. My legs feel like weights. My face twitches, my eye winks and I can't swallow. Relax and sleep by natures made has been a life saver. It has melatonin, valerian root and chamomile. As a matter a fact I was in remission for a year. I only had subtle movements. I posted the discovery on youtube and other people have reported improvements. Mainly I wanted to know if the shingles triggered this episode because it effects the nerves? My grandmother developed alzheimer's late in life. I'm 49 years of age. Something is wrong. I can feel it.
- My t.d. and my living hell (3 responses)
I was dianosed with T.D. on Sept. 19, 2013...by a neurologist at St. Peters Hospital in Albany, NY...I was taken there because of concern that I had suffered a stroke...since then, life for, not only me, but my family has pretty much come to a screeching halt...I seemed to have hit the jackpot as far as the symptoms go, getting most associated w/ T.D. w/ the exception of rapid eye movement...my speech comes and goes, I have head tilting (to the right), very difficult to watch TV...I constantly drool, creating secondary problems w/ my mouth...(open sores inside of my mouth, terrible pain at times, very painful pimples on my chin an lips, etc.)extremely fatigue...hand and feet movement, uncontrolled stepping or marching in place...and the list goes on...I go to medical professionals all of the time and do not get much satisfaction...I try medications without much success...(all of this is getting very expensive)...My next move is to try heavy doses of Amino Acids...(not covered by ins. and $120.00+ per month...my Primary suggested a Case Manager because he feels that I may not be getting the best treatment I could be getting...right now, I'm losing confidence in everything...I DO know that it sucks to be me right now...
- Mother recovered significantly from confusion (1 response)
My very independent, active mother was diagnosed with Parkinson's (long over due, she did not have the common tremor but instead had issues with her gait).
She was already on Wellbutrin and Prozac because they thought her shuffling was muscle weakness due to inactivity caused by depression. Once properly diagnosed and under the treatment of a neurologist for Parkinson's she was prescribed Sinemet. Her ability to walk increased dramatically however she was extremely confused. She constantly wanted to go home even though she was. She would get angry with us if we tried to convince her otherwise. She confused family members with other people and thought very off the wall situations were occurring with them. The neurologist said she had common symptoms of senile dementia which can accompany Parkinson's patients. Due to a random ordered hearing/vertigo test, we were instructed to take her off of all her medications a week prior to the test. Because the sinemet was so difficult to get her to tolerate due to extreme nausea I did not take her off of it but I took her off everything else. Within four to five days of being off the depression medication which had been combined with the sinemet she had a 360 degree turnaround in her confusion. She was even able to tell me that she knew she was confused but could not reason herself out of it. It was an end to eight months of pure H**. If you have a family suffering confusion and symptoms of senility that is on Sinemet and also taking anti-depression medications, insist that they be weaned of the anti-depressants before you accept the senility diagnosis.
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Comments from related studies:
From this study (4 weeks ago):
Hyperventilating, severe dyskinesia at same time. Not sure if from under medication or over medication. We not sure where the dyskinesia travels in the body
From this study (2 months ago):
Had HHT with higher frequency of nose bleeds with age. After being diagnosed with Parkinson about 5 years ago taking carbidopa levodopa 3 times a day, nose bleeds decreased significantly
From this study (3 months ago):
Caley on Oct, 20, 2014:
My son is 11 and was on invega for 2 years. He has came down with tardive dyskinesia. In a matter of weeks he had shoulder movements and now severe head jerking. I want to just stop the Invega but my doctor says the movements could get worse and wants to do it a course of a month. My feeling is the longer he is on it the medication the more possibility for it to be permanent. Please any advice, should I just stop the Invega. My little boy is suffering. I'm scared to death this won't go away. Please help.
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