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Review: could Carboplatin cause Anaphylaxis?

Summary: Anaphylaxis could be caused by Carboplatin, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take Taxol, and have Ovarian cancer.

We study 28,839 people who have side effects while taking Carboplatin from FDA and social media. Among them, 271 have Anaphylaxis. Find out below who they are, when they have Anaphylaxis and more.

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Carboplatin

Carboplatin (latest outcomes from 28,927 users) has active ingredients of carboplatin. It is often used in cancer.

Anaphylaxis

Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death) (latest reports from 107,180 patients) has been reported by people with multiple sclerosis, asthma, high blood pressure, premedication, pain.

On Apr, 14, 2014: 28,834 people reported to have side effects when taking Carboplatin. Among them, 271 people (0.94%) have Anaphylaxis. They amount to 0.25% of all the 107,117 people who have Anaphylaxis on eHealthMe.

Trend of Anaphylaxis in Carboplatin reports

Time on Carboplatin when people have Anaphylaxis * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Anaphylaxis82.18%14.85%0.99%0.99%0.99%0.00%0.00%

Gender of people who have Anaphylaxis when taking Carboplatin * :

FemaleMale
Anaphylaxis75.61%24.39%

Age of people who have Anaphylaxis when taking Carboplatin * :

0-12-910-1920-2930-3940-4950-5960+
Anaphylaxis0.42%2.93%0.84%1.26%2.09%5.86%31.80%54.81%

Severity of Anaphylaxis when taking Carboplatin ** :

leastmoderateseveremost severe
Anaphylaxis0.00%100.00%0.00%0.00%

How people recovered from Anaphylaxis ** :

while on the drugafter off the drugnot yet
Anaphylaxis100.00%0.00%0.00%

Top conditions involved for these people * :

  1. Ovarian cancer (70 people, 25.83%)
  2. Non-small cell lung cancer (25 people, 9.23%)
  3. Breast cancer (10 people, 3.69%)
  4. Hypersensitivity (9 people, 3.32%)
  5. Lung neoplasm malignant (9 people, 3.32%)

Top co-used drugs for these people * :

  1. Taxol (65 people, 23.99%)
  2. Paclitaxel (55 people, 20.30%)
  3. Dexamethasone (33 people, 12.18%)
  4. Zantac (31 people, 11.44%)
  5. Decadron (27 people, 9.96%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Carboplatin, Anaphylaxis

You can also:

On eHealthMe, Carboplatin (carboplatin) is often used for cancer. Find out below the conditions Carboplatin is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Carboplatin used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (3 weeks ago):

  • I went to the emergency room because I noticed that the bottom of my face was swollen on the right side next to my chin. I was not in any pain, but thought it was strange and because I had never noticed anything like that before. The doctor was not sure what was wrong with me, said he thought it was a blocked salivary gland, and prescribed me ciproflaxin and clyndamyacin. I have been perscribed both medications at seperate times no more than 2 years before this happened without having any marked adverse response. I filled the perscriptions immediately after leaving the hospital and took them once I arrived at home. Shortly, (10-40 minutes - less than one hour) after I took both pills together as instructed at the hospital, I started having extreme stomach pain and cramps, so extreme that i was writhing in pain and said that i felt like i had been poisoned. I lay down to try to go to bed becasue i was in so much pain, and woke up 1-2 hours later, itching more severely than ever before everywhere on my body including my scalp, the palms of my hands, and the soles of my feet. When I turned on the light I saw that my entire body was completely red and covered with hives, then my face started swelling up, my lips, cheeks, eyes, it seemed like my entire head was swelling. I'm not certain if my tongue was swelling or if i started having a panic attack that made it seem difficult to breathe (i have had panic attacks before). went to emergency room was treated with epi-pen, pepcid, benadryl, among other meds i cannot recall. nothing like this has ever occured before or since.

    Reply

  • From this study (1 month ago):

  • Anaphylactic shock upon first and second infusions. Crash team intervention required

    Bilateral Pulmonary embolisms at 4th week of treatment

    Chronic and multiple episodes of accute Hypotension started during Rituximab treatments. No hypoentention problems prior to Rituximab treatments.

    Reply

  • From this study (3 months ago):

  • Have some constipation with aching abdominal bloating, some stomach pain

    Reply

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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