Review: could Carboplatin cause Anaphylaxis?


Summary

Anaphylaxis is found among people who take Carboplatin, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Taxol, and have Ovarian cancer . We study 28,409 people who have side effects while taking Carboplatin from FDA and social media. Among them, 286 have Anaphylaxis. Find out below who they are, when they have Anaphylaxis and more.

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Carboplatin

Carboplatin has active ingredients of carboplatin. It is often used in lung cancer - non-small cell. (latest outcomes from Carboplatin 28,476 users)

Anaphylaxis

Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death) has been reported by people with injection site haematoma, hypotension, rashes, ventricular tachycardia, drug ineffective (latest reports from 28,282 Anaphylaxis patients).

On Jul, 21, 2016

28,409 people reported to have side effects when taking Carboplatin.
Among them, 286 people (1.01%) have Anaphylaxis


Number of reports submitted per year:

Could Carboplatin cause Anaphylaxis?

Time on Carboplatin when people have Anaphylaxis *:

  • < 1 month: 81.19 %
  • 1 - 6 months: 15.84 %
  • 6 - 12 months: 0.99 %
  • 1 - 2 years: 0.99 %
  • 2 - 5 years: 0.99 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Anaphylaxis when taking Carboplatin *:

  • female: 73.95 %
  • male: 26.05 %

Age of people who have Anaphylaxis when taking Carboplatin *:

  • 0-1: 0.46 %
  • 2-9: 3.2 %
  • 10-19: 0.91 %
  • 20-29: 1.37 %
  • 30-39: 1.83 %
  • 40-49: 5.48 %
  • 50-59: 28.77 %
  • 60+: 57.99 %

Severity if Anaphylaxis when taking Carboplatin **:

  • least: 0.0 %
  • moderate: 100 %
  • severe: 0.0 %
  • most severe: 0.0 %

How people recovered from Anaphylaxis **:

  • while on drug: 100 %
  • after off the drug: 0.0 %
  • not yet: 0.0 %

Top conditions involved for these people *:

  • Ovarian Cancer (46 people)
  • Non-Small Cell Lung Cancer (25 people)
  • Lung Neoplasm Malignant (9 people)
  • Prophylaxis (8 people)
  • Glioma (8 people)

Top co-used drugs for these people *:

  • Taxol (61 people)
  • Paclitaxel (45 people)
  • Dexamethasone (33 people)
  • Zantac (27 people)
  • Decadron (26 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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