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Review: could Cefazolin cause Anaphylaxis?

Summary: Anaphylaxis could be caused by Cefazolin, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take Propofol, and have Anaesthesia.

We study 5,887 people who have side effects while taking Cefazolin from FDA and social media. Among them, 337 have Anaphylaxis. Find out below who they are, when they have Anaphylaxis and more.

On Apr, 9, 2014: 5,884 people reported to have side effects when taking Cefazolin. Among them, 337 people (5.73%) have Anaphylaxis. They amount to 0.32% of all the 106,930 people who have Anaphylaxis on eHealthMe.

Trend of Anaphylaxis in Cefazolin reports

Time on Cefazolin when people have Anaphylaxis * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Anaphylaxis100.00%0.00%0.00%0.00%0.00%0.00%0.00%

Gender of people who have Anaphylaxis when taking Cefazolin * :

FemaleMale
Anaphylaxis60.17%39.83%

Age of people who have Anaphylaxis when taking Cefazolin * :

0-12-910-1920-2930-3940-4950-5960+
Anaphylaxis0.00%1.27%5.73%7.01%19.11%12.74%12.74%41.40%

Severity of Anaphylaxis when taking Cefazolin ** :

n/a

How people recovered from Anaphylaxis ** :

n/a

Top conditions involved for these people * :

  1. Anaesthesia (47 people, 13.95%)
  2. Prophylaxis (26 people, 7.72%)
  3. General anaesthesia (16 people, 4.75%)
  4. Hypertension (5 people, 1.48%)
  5. Atrial fibrillation (4 people, 1.19%)

Top co-used drugs for these people * :

  1. Propofol (70 people, 20.77%)
  2. Cefazolin sodium (55 people, 16.32%)
  3. Diprivan (54 people, 16.02%)
  4. Midazolam hcl (34 people, 10.09%)
  5. Vecuronium bromide (32 people, 9.50%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Cefazolin, Anaphylaxis

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Comments from related studies:

  • From this study (2 weeks ago):

  • I went to the emergency room because I noticed that the bottom of my face was swollen on the right side next to my chin. I was not in any pain, but thought it was strange and because I had never noticed anything like that before. The doctor was not sure what was wrong with me, said he thought it was a blocked salivary gland, and prescribed me ciproflaxin and clyndamyacin. I have been perscribed both medications at seperate times no more than 2 years before this happened without having any marked adverse response. I filled the perscriptions immediately after leaving the hospital and took them once I arrived at home. Shortly, (10-40 minutes - less than one hour) after I took both pills together as instructed at the hospital, I started having extreme stomach pain and cramps, so extreme that i was writhing in pain and said that i felt like i had been poisoned. I lay down to try to go to bed becasue i was in so much pain, and woke up 1-2 hours later, itching more severely than ever before everywhere on my body including my scalp, the palms of my hands, and the soles of my feet. When I turned on the light I saw that my entire body was completely red and covered with hives, then my face started swelling up, my lips, cheeks, eyes, it seemed like my entire head was swelling. I'm not certain if my tongue was swelling or if i started having a panic attack that made it seem difficult to breathe (i have had panic attacks before). went to emergency room was treated with epi-pen, pepcid, benadryl, among other meds i cannot recall. nothing like this has ever occured before or since.

    Reply

  • From this study (1 month ago):

  • Anaphylactic shock upon first and second infusions. Crash team intervention required

    Bilateral Pulmonary embolisms at 4th week of treatment

    Chronic and multiple episodes of accute Hypotension started during Rituximab treatments. No hypoentention problems prior to Rituximab treatments.

    Reply

  • From this study (3 months ago):

  • After being put on sertriline.citralopam.buspirone.fluoxetine and flupentixol for mild anxiaty I becamereally ill since comeing off these meds I feel alot better but not cured

    Reply

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