Review: could Celebrex cause Stevens-johnson Syndrome?


Summary

Stevens-johnson syndrome is found among people who take Celebrex, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Bextra, and have Ill-defined disorder . We study 93,750 people who have side effects while taking Celebrex from FDA and social media. Among them, 545 have Stevens-johnson syndrome. Find out below who they are, when they have Stevens-johnson syndrome and more.

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Celebrex

Celebrex has active ingredients of celecoxib. It is often used in arthritis. (latest outcomes from Celebrex 95,401 users)

Stevens-johnson Syndrome

Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe) has been reported by people with blister, breathing difficulty, erythema multiforme, fever, thrombocytopenia (latest reports from 34,325 Stevens-johnson syndrome patients).

On Sep, 18, 2016

93,750 people reported to have side effects when taking Celebrex.
Among them, 545 people (0.58%) have Stevens-johnson Syndrome


Number of reports submitted per year:

Could Celebrex cause Stevens-johnson syndrome?

Time on Celebrex when people have Stevens-johnson Syndrome *:

  • < 1 month: 56.15 %
  • 1 - 6 months: 13.08 %
  • 6 - 12 months: 10.77 %
  • 1 - 2 years: 8.46 %
  • 2 - 5 years: 11.54 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Stevens-johnson Syndrome when taking Celebrex *:

  • female: 65.62 %
  • male: 34.38 %

Age of people who have Stevens-johnson Syndrome when taking Celebrex *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.6 %
  • 20-29: 3.58 %
  • 30-39: 5.67 %
  • 40-49: 21.19 %
  • 50-59: 16.42 %
  • 60+: 52.54 %

Severity if Stevens-johnson Syndrome when taking Celebrex **:

  • least: 0.0 %
  • moderate: 0.0 %
  • severe: 50 %
  • most severe: 50 %

How people recovered from Stevens-johnson Syndrome **:

  • while on drug: 50 %
  • after off the drug: 0.0 %
  • not yet: 50 %

Top conditions involved for these people *:

  • Ill-Defined Disorder (38 people, 6.97%)
  • Pain (32 people, 5.87%)
  • Arthritis (32 people, 5.87%)
  • Osteoarthritis (28 people, 5.14%)
  • Arthralgia (22 people, 4.04%)

Top co-used drugs for these people *:

  • Bextra (121 people, 22.20%)
  • Vioxx (50 people, 9.17%)
  • Norvasc (31 people, 5.69%)
  • Lipitor (31 people, 5.69%)
  • Acetaminophen (30 people, 5.50%)

Top other side effects for these people *:

  • Myocardial Infarction (103 people, 18.90%)
  • Thrombosis (93 people, 17.06%)
  • Pulmonary Embolism (87 people, 15.96%)
  • Organ Failure (86 people, 15.78%)
  • Cerebrovascular Accident (86 people, 15.78%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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