Review: could Celebrex cause Stevens-johnson Syndrome?


Summary

Stevens-johnson syndrome is found among people who take Celebrex, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Bextra, and have Ill-defined disorder . We study 81,554 people who have side effects while taking Celebrex from FDA and social media. Among them, 536 have Stevens-johnson syndrome. Find out below who they are, when they have Stevens-johnson syndrome and more.

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Celebrex

Celebrex has active ingredients of celecoxib. It is often used in arthritis. (latest outcomes from Celebrex 83,109 users)

Stevens-johnson Syndrome

Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe) has been reported by people with breathing difficulty, suicidal ideation, hypotension, pleural effusion, systemic lupus erythematosus (latest reports from 30,448 Stevens-johnson syndrome patients).

On Aug, 27, 2016

81,554 people reported to have side effects when taking Celebrex.
Among them, 536 people (0.66%) have Stevens-johnson Syndrome


Number of reports submitted per year:

Could Celebrex cause Stevens-johnson syndrome?

Time on Celebrex when people have Stevens-johnson Syndrome *:

  • < 1 month: 57.69 %
  • 1 - 6 months: 12.31 %
  • 6 - 12 months: 10.77 %
  • 1 - 2 years: 7.69 %
  • 2 - 5 years: 11.54 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Stevens-johnson Syndrome when taking Celebrex *:

  • female: 65.4 %
  • male: 34.6 %

Age of people who have Stevens-johnson Syndrome when taking Celebrex *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.3 %
  • 20-29: 3.66 %
  • 30-39: 5.49 %
  • 40-49: 21.65 %
  • 50-59: 15.85 %
  • 60+: 53.05 %

Severity if Stevens-johnson Syndrome when taking Celebrex **:

  • least: 0.0 %
  • moderate: 0.0 %
  • severe: 50 %
  • most severe: 50 %

How people recovered from Stevens-johnson Syndrome **:

  • while on drug: 50 %
  • after off the drug: 0.0 %
  • not yet: 50 %

Top conditions involved for these people *:

  • Ill-Defined Disorder (38 people)
  • Pain (30 people)
  • Arthritis (30 people)
  • Osteoarthritis (28 people)
  • Arthralgia (21 people)

Top co-used drugs for these people *:

  • Bextra (121 people)
  • Vioxx (50 people)
  • Norvasc (31 people)
  • Lipitor (31 people)
  • Acetaminophen (29 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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