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Review: could Cisplatin cause Macrocytosis?

Summary: Macrocytosis could be caused by Cisplatin, especially for people who are female, 20-29 old, have been taking the drug for < 1 month, also take 6-mercaptopurine, and have Small cell lung cancer limited stage.

We study people who have side effects while taking Cisplatin from FDA and social media. Among them, 3 have Macrocytosis. Find out below who they are, when they have Macrocytosis and more.

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Cisplatin

Cisplatin (latest outcomes from 35,643 users) has active ingredients of cisplatin. It is often used in chemotherapy.

Macrocytosis

Macrocytosis (enlargement of red blood cells with near-constant haemoglobin concentration) (latest reports from 7,911 patients) has been reported by people with hiv infection, osteoporosis, osteopenia, depression, antiviral.

On Apr, 8, 2014: 35,593 people reported to have side effects when taking Cisplatin. Among them, 3 people (0.01%) have Macrocytosis. They amount to 0.04% of all the 7,884 people who have Macrocytosis on eHealthMe.

Trend of Macrocytosis in Cisplatin reports

Time on Cisplatin when people have Macrocytosis * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Macrocytosis100.00%0.00%0.00%0.00%0.00%0.00%0.00%

Age of people who have Macrocytosis when taking Cisplatin * :

0-12-910-1920-2930-3940-4950-5960+
Macrocytosis0.00%0.00%0.00%33.33%0.00%0.00%33.33%33.33%

Severity of Macrocytosis when taking Cisplatin ** :

n/a

How people recovered from Macrocytosis ** :

n/a

Top conditions involved for these people * :

  1. Small cell lung cancer limited stage (1 people, 33.33%)
  2. Gastric cancer (1 people, 33.33%)

Top co-used drugs for these people * :

  1. 6-mercaptopurine (1 people, 33.33%)
  2. Tamoxifen citrate (1 people, 33.33%)
  3. Vepesid (1 people, 33.33%)
  4. Bcnu (1 people, 33.33%)
  5. Mutamycin (1 people, 33.33%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Cisplatin, Macrocytosis

You can also:

On eHealthMe, Cisplatin (cisplatin) is often used for chemotherapy. Find out below the conditions Cisplatin is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Cisplatin used for and how effective is it:

Other drugs that are used to treat the same conditions:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (2 months ago):

  • Have read somewhere that the use of omeprazole can cause macrocytosis.
    Is this a possibility?

    Reply

  • From this study (3 months ago):

  • Altho my doctor is an excellent surgeon, he does not want to discuss food interactions with the chemotherapy drugs ... so I am doing it myself. I already know to not eat citrus fruits or drink green tea during the 4.5 months of chemo but what else should I avoid eating?

    Reply

  • From this study (5 months ago):

  • Neulasta was used after a 4-day course of VD-PACE (velcade, dexamethasone, doxorubicin, cisplatin, cytoxan, etoposide) to regenerate white blood cells. On day 5 after neulasta I had intense lower back pain in pulsating waves that lasted for 1 day. It was day 8 after treatment VD-PACE ended

    4 weeks later the VD-PACE cycle was repeated. This time, in preparation for stem cell collection, I received daily high dose shots of of neupogen. On day 6 I started having the same lower back pain I now identified as kidney stones. It lasted for under 2 days and the EXTREMELY painful symptoms disappeared completely again. Symptoms started 8 days after VD-PACE treatment ended

    Reply

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More questions for: Cisplatin, Macrocytosis

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