Cladribine and Spleen enlargement - from FDA reports


Spleen enlargement is found among people who take Cladribine, especially for people who are female, 2-9 old also take medication Cytarabine, and have Burkitt lymphoma. This review analyzes which people have Spleen enlargement with Cladribine. It is created by eHealthMe based on reports of 1,026 people who have side effects when taking Cladribine from FDA, and is updated regularly.

What to expect?

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On Jun, 19, 2017

1,026 people reported to have side effects when taking Cladribine.
Among them, 7 people (0.68%) have Spleen enlargement

Number of reports submitted per year:

Could Cladribine cause Spleen enlargement?

Gender of people who have Spleen enlargement when taking Cladribine *:

  • female: 83.33 %
  • male: 16.67 %

Age of people who have Spleen enlargement when taking Cladribine *:

  • 0-1: 0.0 %
  • 2-9: 50.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 33.33 %
  • 60+: 16.67 %

Top conditions involved for these people *:

  • Myelodysplastic Syndrome (1 person, 14.29%)
  • Malignant Histiocytosis (1 person, 14.29%)
  • Langerhans' Cell Granulomatosis (1 person, 14.29%)
  • Hairy Cell Leukaemia (1 person, 14.29%)
  • Burkitt Lymphoma (1 person, 14.29%)

Top co-used drugs for these people *:

  • Vinblastine Sulfate (3 people, 42.86%)
  • Methotrexate (3 people, 42.86%)
  • Mercaptopurine (3 people, 42.86%)
  • Etoposide (3 people, 42.86%)
  • Cytarabine (3 people, 42.86%)

Top other side effects for these people *:

  • Fever (4 people, 57.14%)
  • Thrombocytopenia (3 people, 42.86%)
  • Lymph Follicular Hypertrophy (3 people, 42.86%)
  • Interstitial Lung Disease (3 people, 42.86%)
  • Anaphylaxis (3 people, 42.86%)

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Spleen enlargement when taking Cladribine?


Cladribine has active ingredients of cladribine. (latest outcomes from Cladribine 1,030 users)

Spleen enlargement

Spleen enlargement has been reported by people with primary myelofibrosis, rheumatoid arthritis, chronic myeloid leukaemia, hiv infection, high blood pressure (latest reports from 8,767 Spleen enlargement patients).

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What would happen?

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