Cladribine and Splenomegaly - from FDA reports


Splenomegaly is found among people who take Cladribine, especially for people who are female, 2-9 old also take medication Cytarabine, and have Burkitt lymphoma. This review analyzes which people have Splenomegaly with Cladribine. It is created by eHealthMe based on reports of 1,058 people who have side effects when taking Cladribine from FDA , and is updated regularly.

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On Oct, 22, 2017

1,058 people reported to have side effects when taking Cladribine.
Among them, 7 people (0.66%) have Splenomegaly

Number of reports submitted per year:

Could Cladribine cause Splenomegaly?

Gender of people who have Splenomegaly when taking Cladribine *:

  • female: 83.33 %
  • male: 16.67 %

Age of people who have Splenomegaly when taking Cladribine *:

  • 0-1: 0.0 %
  • 2-9: 50.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 33.33 %
  • 60+: 16.67 %

Top conditions involved for these people *:

  • Myelodysplastic Syndrome (1 person, 14.29%)
  • Malignant Histiocytosis (1 person, 14.29%)
  • Langerhans' Cell Granulomatosis (1 person, 14.29%)
  • Hairy Cell Leukaemia (1 person, 14.29%)
  • Burkitt Lymphoma (1 person, 14.29%)

Top co-used drugs for these people *:

  • Vinblastine Sulfate (3 people, 42.86%)
  • Methotrexate (3 people, 42.86%)
  • Mercaptopurine (3 people, 42.86%)
  • Etoposide (3 people, 42.86%)
  • Cytarabine (3 people, 42.86%)

Top other side effects for these people *:

  • Fever (4 people, 57.14%)
  • Thrombocytopenia (3 people, 42.86%)
  • Lymph Follicular Hypertrophy (3 people, 42.86%)
  • Interstitial Lung Disease (3 people, 42.86%)
  • Anaphylaxis (3 people, 42.86%)

* Approximation only. Some reports may have incomplete information.

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Do you have Splenomegaly when taking Cladribine?

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Splenomegaly and drugs with ingredients of cladribine.

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Splenomegaly and Cladribine from FDA and eHealthMe reports


Cladribine has active ingredients of cladribine. (latest outcomes from Cladribine 1,062 users)


Splenomegaly (enlargement of spleen) has been reported by people with primary myelofibrosis, rheumatoid arthritis, chronic myeloid leukaemia, hiv infection, high blood pressure (latest reports from 9,022 Splenomegaly patients).

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