Review: could Clonazepam cause Serotonin Syndrome?


Serotonin syndrome is found among people who take Clonazepam, especially for people who are female, 60+ old , have been taking the drug for 1 - 6 months, also take medication Lorazepam, and have Depression . We study 44,881 people who have side effects while taking Clonazepam from FDA and social media. Among them, 304 have Serotonin syndrome. Find out below who they are, when they have Serotonin syndrome and more.

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Clonazepam has active ingredients of clonazepam. It is often used in stress and anxiety. (latest outcomes from Clonazepam 45,597 users)

Serotonin Syndrome

Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time) has been reported by people with disease complication, insomnia, feeling jittery, vaginal discharge, bruxism (latest reports from 7,451 Serotonin syndrome patients).

On Aug, 24, 2016

44,881 people reported to have side effects when taking Clonazepam.
Among them, 304 people (0.68%) have Serotonin Syndrome

Number of reports submitted per year:

Could Clonazepam cause Serotonin syndrome?

Time on Clonazepam when people have Serotonin Syndrome *:

  • < 1 month: 4.35 %
  • 1 - 6 months: 84.78 %
  • 6 - 12 months: 2.17 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 6.52 %
  • 5 - 10 years: 2.17 %
  • 10+ years: 0.0 %

Gender of people who have Serotonin Syndrome when taking Clonazepam *:

  • female: 70.07 %
  • male: 29.93 %

Age of people who have Serotonin Syndrome when taking Clonazepam *:

  • 0-1: 0.0 %
  • 2-9: 0.35 %
  • 10-19: 3.89 %
  • 20-29: 13.78 %
  • 30-39: 24.38 %
  • 40-49: 19.08 %
  • 50-59: 13.43 %
  • 60+: 25.09 %

Severity if Serotonin Syndrome when taking Clonazepam **:

  • least: 0.0 %
  • moderate: 0.0 %
  • severe: 100 %
  • most severe: 0.0 %

How people recovered from Serotonin Syndrome **:

  • while on drug: 0.0 %
  • after off the drug: 0.0 %
  • not yet: 100 %

Top conditions involved for these people *:

  • Depression (110 people)
  • Neck Pain (40 people)
  • Analgesic Therapy (37 people)
  • Sedation (36 people)
  • Psychotic Disorder (36 people)

Top co-used drugs for these people *:

  • Lorazepam (77 people)
  • Omeprazole (73 people)
  • Quetiapine (62 people)
  • Mirtazapine (58 people)
  • Paroxetine Hcl (56 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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