Clonazepam and Serotonin syndrome - from FDA reports


Summary

Serotonin syndrome is found among people who take Clonazepam, especially for people who are female, 60+ old , have been taking the drug for 1 - 6 months, also take medication Lorazepam, and have Depression . We study 58,007 people who have side effects while taking Clonazepam from FDA. Among them, 400 have Serotonin syndrome. Find out below who they are, when they have Serotonin syndrome and more.

What to expect?

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Clonazepam

Clonazepam has active ingredients of clonazepam. It is often used in stress and anxiety. (latest outcomes from Clonazepam 62,632 users)

Serotonin Syndrome

Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time) has been reported by people with depression, pain, stress and anxiety, major depression, insomnia (latest reports from 9,744 Serotonin syndrome patients).

On Feb, 14, 2017

58,007 people reported to have side effects when taking Clonazepam.
Among them, 400 people (0.69%) have Serotonin Syndrome


Number of reports submitted per year:

Could Clonazepam cause Serotonin syndrome?

Time on Clonazepam when people have Serotonin Syndrome *:

  • < 1 month: 2.27 %
  • 1 - 6 months: 97.73 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Serotonin Syndrome when taking Clonazepam *:

  • female: 64.64 %
  • male: 35.36 %

Age of people who have Serotonin Syndrome when taking Clonazepam *:

  • 0-1: 0.0 %
  • 2-9: 0.27 %
  • 10-19: 7.36 %
  • 20-29: 14.44 %
  • 30-39: 20.16 %
  • 40-49: 20.98 %
  • 50-59: 12.53 %
  • 60+: 24.25 %

Top conditions involved for these people *:

  • Depression (123 people, 30.75%)
  • Sedation (46 people, 11.50%)
  • Analgesic Therapy (46 people, 11.50%)
  • Neck Pain (43 people, 10.75%)
  • Psychotic Disorder (41 people, 10.25%)

Top co-used drugs for these people *:

  • Lorazepam (77 people, 19.25%)
  • Omeprazole (74 people, 18.50%)
  • Mirtazapine (59 people, 14.75%)
  • Ondansetron (56 people, 14.00%)
  • Diazepam (55 people, 13.75%)

Top other side effects for these people *:

  • Agitation (121 people, 30.25%)
  • Fever (85 people, 21.25%)
  • Tremor (82 people, 20.50%)
  • Hyperhidrosis (81 people, 20.25%)
  • Neuroleptic Malignant Syndrome (77 people, 19.25%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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