Clonazepam and Serotonin syndrome - from FDA reports


Summary

Serotonin syndrome is found among people who take Clonazepam, especially for people who are female, 60+ old , have been taking the drug for 1 - 6 months, also take medication Lorazepam, and have Depression. This review analyzes which people have Serotonin syndrome with Clonazepam. It is created by eHealthMe based on reports of 64,716 people who have side effects when taking Clonazepam from FDA , and is updated regularly.

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On Sep, 20, 2017

64,716 people reported to have side effects when taking Clonazepam.
Among them, 421 people (0.65%) have Serotonin syndrome


Number of reports submitted per year:

Could Clonazepam cause Serotonin syndrome?

Time on Clonazepam when people have Serotonin syndrome *:

  • < 1 month: 2.27 %
  • 1 - 6 months: 97.73 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Serotonin syndrome when taking Clonazepam *:

  • female: 66.08 %
  • male: 33.92 %

Age of people who have Serotonin syndrome when taking Clonazepam *:

  • 0-1: 0.0 %
  • 2-9: 0.26 %
  • 10-19: 7.03 %
  • 20-29: 14.58 %
  • 30-39: 19.27 %
  • 40-49: 20.31 %
  • 50-59: 11.98 %
  • 60+: 26.56 %

Top conditions involved for these people *:

  • Depression (124 people, 29.45%)
  • Sedation (47 people, 11.16%)
  • Analgesic Therapy (46 people, 10.93%)
  • Neck Pain (43 people, 10.21%)
  • Psychotic Disorder (42 people, 9.98%)

Top co-used drugs for these people *:

  • Lorazepam (77 people, 18.29%)
  • Omeprazole (74 people, 17.58%)
  • Mirtazapine (59 people, 14.01%)
  • Ondansetron (56 people, 13.30%)
  • Diazepam (55 people, 13.06%)

Top other side effects for these people *:

  • Agitation (122 people, 28.98%)
  • Fever (85 people, 20.19%)
  • Hyperhidrosis (83 people, 19.71%)
  • Tremor (82 people, 19.48%)
  • Neuroleptic Malignant Syndrome (77 people, 18.29%)

* Approximation only. Some reports may have incomplete information.

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Serotonin syndrome and Clonazepam from FDA and eHealthMe reports

Clonazepam

Clonazepam has active ingredients of clonazepam. It is often used in stress and anxiety. (latest outcomes from Clonazepam 69,506 users)

Serotonin syndrome

Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time) has been reported by people with depression, pain, stress and anxiety, major depression, insomnia (latest reports from 10,388 Serotonin syndrome patients).

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