Clozapine and Delirium - from FDA reports


Summary

Delirium is found among people who take Clozapine, especially for people who are male, 50-59 old , have been taking the drug for < 1 month, also take medication Abilify, and have Schizophrenia . We study 26,851 people who have side effects while taking Clozapine from FDA. Among them, 271 have Delirium. Find out below who they are, when they have Delirium and more.

What to expect?

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Clozapine

Clozapine has active ingredients of clozapine. It is often used in schizophrenia. (latest outcomes from Clozapine 27,129 users)

Delirium

Delirium (wild excitement) has been reported by people with depression, pain, high blood pressure, insomnia, cancer pain (latest reports from 20,561 Delirium patients).

On Feb, 26, 2017

26,851 people reported to have side effects when taking Clozapine.
Among them, 271 people (1.01%) have Delirium


Number of reports submitted per year:

Could Clozapine cause Delirium?

Time on Clozapine when people have Delirium *:

  • < 1 month: 32.56 %
  • 1 - 6 months: 18.6 %
  • 6 - 12 months: 9.3 %
  • 1 - 2 years: 13.95 %
  • 2 - 5 years: 13.95 %
  • 5 - 10 years: 6.98 %
  • 10+ years: 4.65 %

Gender of people who have Delirium when taking Clozapine *:

  • female: 37.55 %
  • male: 62.45 %

Age of people who have Delirium when taking Clozapine *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 3.57 %
  • 20-29: 11.61 %
  • 30-39: 23.21 %
  • 40-49: 16.07 %
  • 50-59: 27.23 %
  • 60+: 18.3 %

Top conditions involved for these people *:

  • Schizophrenia (66 people, 24.35%)
  • Schizoaffective Disorder (27 people, 9.96%)
  • Psychotic Disorder (22 people, 8.12%)
  • Schizophrenia, Paranoid Type (20 people, 7.38%)
  • Depression (12 people, 4.43%)

Top co-used drugs for these people *:

  • Abilify (22 people, 8.12%)
  • Olanzapine (19 people, 7.01%)
  • Seroquel (18 people, 6.64%)
  • Risperdal (18 people, 6.64%)
  • Valproic Acid (16 people, 5.90%)

Top other side effects for these people *:

  • Confusional State (58 people, 21.40%)
  • Agitation (57 people, 21.03%)
  • Fever (43 people, 15.87%)
  • Drowsiness (38 people, 14.02%)
  • Confusion (33 people, 12.18%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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