Review: could Clozapine cause Delirium?


Delirium is found among people who take Clozapine, especially for people who are male, 50-59 old , have been taking the drug for < 1 month, also take medication Olanzapine, and have Schizophrenia . We study 22,694 people who have side effects while taking Clozapine from FDA and social media. Among them, 212 have Delirium. Find out below who they are, when they have Delirium and more.

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Clozapine has active ingredients of clozapine. It is often used in schizophrenia. (latest outcomes from Clozapine 22,813 users)


Delirium (wild excitement) has been reported by people with fever, agitation, confusional state, respiratory depression, drowsiness (latest reports from 15,789 Delirium patients).

On Aug, 22, 2016

22,694 people reported to have side effects when taking Clozapine.
Among them, 212 people (0.93%) have Delirium

Number of reports submitted per year:

Could Clozapine cause Delirium?

Time on Clozapine when people have Delirium *:

  • < 1 month: 28.57 %
  • 1 - 6 months: 11.43 %
  • 6 - 12 months: 11.43 %
  • 1 - 2 years: 14.29 %
  • 2 - 5 years: 17.14 %
  • 5 - 10 years: 8.57 %
  • 10+ years: 8.57 %

Gender of people who have Delirium when taking Clozapine *:

  • female: 37.98 %
  • male: 62.02 %

Age of people who have Delirium when taking Clozapine *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 3.95 %
  • 20-29: 12.99 %
  • 30-39: 20.9 %
  • 40-49: 19.77 %
  • 50-59: 22.03 %
  • 60+: 20.34 %

Top conditions involved for these people *:

  • Schizophrenia (54 people)
  • Schizoaffective Disorder (19 people)
  • Schizophrenia, Paranoid Type (18 people)
  • Psychotic Disorder (13 people)
  • Anxiety (7 people)

Top co-used drugs for these people *:

  • Olanzapine (19 people)
  • Seroquel (18 people)
  • Abilify (17 people)
  • Risperdal (16 people)
  • Lorazepam (16 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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