Review: could Cyclosporine cause Interstitial Lung Disease?


Summary

Interstitial lung disease is found among people who take Cyclosporine, especially for people who are male, 60+ old , have been taking the drug for 1 - 6 months, also take medication Prednisolone, and have Interstitial lung disease . We study 25,169 people who have side effects while taking Cyclosporine from FDA and social media. Among them, 286 have Interstitial lung disease. Find out below who they are, when they have Interstitial lung disease and more.

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Cyclosporine

Cyclosporine has active ingredients of cyclosporine. It is often used in kidney transplant. (latest outcomes from Cyclosporine 25,329 users)

Interstitial Lung Disease

Interstitial lung disease has been reported by people with breathing difficulty, fever, renal impairment, aspartate aminotransferase increased, disease progression (latest reports from 22,021 Interstitial lung disease patients).

On Aug, 21, 2016

25,169 people reported to have side effects when taking Cyclosporine.
Among them, 286 people (1.14%) have Interstitial Lung Disease


Number of reports submitted per year:

Could Cyclosporine cause Interstitial lung disease?

Time on Cyclosporine when people have Interstitial Lung Disease *:

  • < 1 month: 37.5 %
  • 1 - 6 months: 41.07 %
  • 6 - 12 months: 7.14 %
  • 1 - 2 years: 5.36 %
  • 2 - 5 years: 8.93 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Interstitial Lung Disease when taking Cyclosporine *:

  • female: 46.27 %
  • male: 53.73 %

Age of people who have Interstitial Lung Disease when taking Cyclosporine *:

  • 0-1: 0.39 %
  • 2-9: 8.98 %
  • 10-19: 6.25 %
  • 20-29: 6.25 %
  • 30-39: 5.08 %
  • 40-49: 12.5 %
  • 50-59: 23.05 %
  • 60+: 37.5 %

Top conditions involved for these people *:

  • Interstitial Lung Disease (51 people)
  • Stem Cell Transplant (30 people)
  • Dermatomyositis (25 people)
  • Prophylaxis (19 people)
  • Bone Marrow Transplant (14 people)

Top co-used drugs for these people *:

  • Prednisolone (89 people)
  • Methotrexate (70 people)
  • Cyclophosphamide (48 people)
  • Methylprednisolone (36 people)
  • Mycophenolate Mofetil (34 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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