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Review: could Cymbalta cause Leg swelling?

Summary: Leg swelling could be caused by Cymbalta, especially for people who are female, 50-59 old, have been taking the drug for 1 - 6 months, also take Vitamin d, and have Depression.

We study 45,578 people who have side effects while taking Cymbalta from FDA and social media. Among them, 15 have Leg swelling. Find out below who they are, when they have Leg swelling and more.

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Cymbalta

Cymbalta (latest outcomes from 48,967 users) has active ingredients of duloxetine hydrochloride. It is often used in depression.

Leg swelling

Leg swelling (latest reports from 3,391 patients) has been reported by people with high blood pressure, high blood cholesterol, depression, pain, gastroesophageal reflux disease.

On Apr, 16, 2014: 45,578 people reported to have side effects when taking Cymbalta. Among them, 15 people (0.03%) have Leg Swelling. They amount to 0.44% of all the 3,383 people who have Leg Swelling on eHealthMe.

Trend of Leg swelling in Cymbalta reports

Time on Cymbalta when people have Leg swelling * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Leg swelling14.29%28.57%14.29%14.29%21.43%7.14%0.00%

Age of people who have Leg swelling when taking Cymbalta * :

0-12-910-1920-2930-3940-4950-5960+
Leg swelling0.00%0.00%0.00%6.67%20.00%13.33%40.00%20.00%

Severity of Leg swelling when taking Cymbalta ** :

leastmoderateseveremost severe
Leg swelling0.00%26.67%53.33%20.00%

How people recovered from Leg swelling ** :

while on the drugafter off the drugnot yet
Leg swelling0.00%9.09%90.91%

Top conditions involved for these people * :

  1. Depression (8 people, 53.33%)
  2. Vitamin d deficiency (2 people, 13.33%)
  3. Pain (2 people, 13.33%)
  4. High blood pressure (2 people, 13.33%)
  5. Fluid retention (2 people, 13.33%)

Top co-used drugs for these people * :

  1. Vitamin d (5 people, 33.33%)
  2. Prednisone (3 people, 20.00%)
  3. Lipitor (2 people, 13.33%)
  4. Bumex (2 people, 13.33%)
  5. Furosemide (2 people, 13.33%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Cymbalta, Leg swelling

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On eHealthMe, Cymbalta (duloxetine hydrochloride) is often used for depression. Find out below the conditions Cymbalta is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Cymbalta used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (5 months ago):

  • Hemoglobin level was 7.4 in September, now at 8.6. Had gastric bypass in 2002, with no previous anemia issues.

    Reply

  • From this study (12 months ago):

  • I was in a MVA 2 1/2 years ago, I was an RN and was left unable to work. 3 months after the MVA I underwent a Hysterectomy found 4th grade Endometriosis with Adhesions. Only able to remove uterus, cervix is stuck to bowel unable to remove both ovaries retained. Underwent 2 rounds of 6 months each of Depro Lupron injections endometriosis symptoms subsided for 6-8 months and has since returned being cyclic for 12-15 days a month. During the time between the mva and hysterectomy 2 week period of stiffness, unable to move easily sent to rhuematologist found to recently had Parvo Recovered from that. Over time Rheumatologist diagnosed with connective tissue disorder started on Plaquenil and Prednisone. Diagnosed with Fibromyalgia. Sent to pain management diagnosed with pelvic floor tension myalgia, vuvlodynia, vaginal spasms, low testosterone and intersticial cystitis. Sent to sexual medicine doctor, found muscle damage from hysterectomy did trigger point injections and physical therapy deep tissue massage. Then I tore ACL and Medial Meniscus, unable to continue with pelvic pain doctor because gait was messing up what they were fixing. routine blood test found K+ to be 2.5 started on supplements of 40 meq a day of K+. Total body swelling started overnight started on Lasix, no improvement changed to Bumex edema decreased, potassium increased to 60 meq a day. I have been on pain medication since the MVA I have gone from Vicodin, valium to Percocet oxicontin, to MS Contin, Methadone, Butrans Patch and Now I am on Exalgo 12 mg once a day with 2 mg of dilaudid at bedtime. This does not seem to be working. I have constant abdominal/pelvic pain, vaginal spasms, bladder pain, kidney pain after the Bumex has worn off. I have developed Peripheral Neuropathy of my feet from taking crestor and hydroxychloroquine together, then they changed me to Lipitor, which is a statin and will do the same, Primary MD disagrees. I have suffered from Depression, anxiety, Panic attacks and migraines for over 10 years these are inherited conditions in Maternal Grandmother and Mother, migraines in Father also. They are now looking at Sjogrens Syndrome. Was on Vitamin B6 new medical journals say women should not take more than 10-50 mg a day-otc bottles say 100mg so pain management said I am suffering from vitamin B3 overdose and serotonin syndrome, trying to cut back on anti depressives and anti anxiety meds, but now is not really the time to do, I have been turned down for disability X2

    Reply

    Priti on May, 7, 2013:

    Become a vegan, leave animal protein, do yoga and chant " Nam myoho renge Kyo". Search the website "Soka Gakkai International" , practice this philosophy and see the results.

    Reply

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