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Review: could Cymbalta cause Restless leg syndrome?

We study 45,529 people who have side effects while taking Cymbalta from FDA and social media. Among them, 320 have Restless leg syndrome. Find out below who they are, when they have Restless leg syndrome and more.

Stay connected: get help anytime and anywhere for people who take Cymbalta and have Restless leg syndrome >>>

Cymbalta

Cymbalta (latest outcomes from 49,102 users) has active ingredients of duloxetine hydrochloride. It is often used in depression.

Restless leg syndrome

Restless leg syndrome (a powerful urge to move your legs) (latest reports from 68,577 patients) has been reported by people with osteoporosis, depression, high blood pressure, pain, stress and anxiety.

On Jul, 12, 2014: 45,517 people reported to have side effects when taking Cymbalta. Among them, 320 people (0.70%) have Restless Leg Syndrome. They amount to 0.47% of all the 68,495 people who have Restless Leg Syndrome on eHealthMe.

Trend of Restless leg syndrome in Cymbalta reports

Time on Cymbalta when people have Restless leg syndrome * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Restless leg syndrome22.97%13.51%9.46%12.16%32.43%8.11%1.35%

Age of people who have Restless leg syndrome when taking Cymbalta * :

0-12-910-1920-2930-3940-4950-5960+
Restless leg syndrome0.00%0.00%0.79%3.94%14.57%18.90%30.31%31.50%

Severity of Restless leg syndrome when taking Cymbalta ** :

leastmoderateseveremost severe
Restless leg syndrome0.00%32.14%50.00%17.86%

How people recovered from Restless leg syndrome ** :

while on the drugafter off the drugnot yet
Restless leg syndrome0.00%20.00%80.00%

Top conditions involved for these people * :

  1. Depression (106 people, 33.12%)
  2. Restless legs syndrome (50 people, 15.62%)
  3. Pain (50 people, 15.62%)
  4. Sleep disorder (39 people, 12.19%)
  5. Muscle spasms (36 people, 11.25%)

Top co-used drugs for these people * :

  1. Neurontin (92 people, 28.75%)
  2. Ambien (81 people, 25.31%)
  3. Lexapro (75 people, 23.44%)
  4. Zometa (62 people, 19.38%)
  5. Lisinopril (59 people, 18.44%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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Comments from related studies:

  • From this study (2 months ago):

  • tired all the time. My muscles ache and I constantly clench my teeth -currently I am wearing a splint given to me by an oral surgeon. --I feel older than I am. A lot older.

    Reply

  • From this study (5 months ago):

  • Have been on Gabapentin for years now. For the past 3-4 yrs, I have had a chronically elevated WBC without evidence of illness. WBCs run 10.5 to 13.0 consistently. Even when on antibiotics, has not dropped below 10.5. Am now wondering if this could be related to Gabapentin. The elevated WBCs have resulted in delay of care for back pain issues. At one time, I tried to get off of gabapentin - was titrating the dose(c my provider's permission). I noticed that the Restless Leg Syndrome that I had been experiencing had disappeared with the lower dose of Gabapentin. Unfortunately, the Meralgia Paresthetica synotoms increased & had to increase the Gabapentin back up. RLS came back with increased dose.

    Reply

  • From this study (5 months ago):

  • Have been on Gabapentin for years now. For the past 3-4 yrs, I have had a chronically elevated WBC without evidence of illness.WBCs run 10.5 tp 13.0 consistanly. Even when on antibiotics, has not dropped below 10.5. Am now wondering if this could be related to Gabapentin. The elevated WBCs have resulted in delay of care for back pain issues. At one time, I tried to get off of gabapentin - was titrating the dose(c my provider's permission). I noticed that the Restless Leg Syndrome that I had been experiencing had disappeared with the lower dose of Gabapentin. Unfortunately, the Meralgia Paresthetica synotoms increase & had to increase the Gabapentin back up. RLS came back with increased dose.

    Reply

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More reviews for: Cymbalta, Restless leg syndrome

On eHealthMe, Cymbalta (duloxetine hydrochloride) is often used for depression. Find out below the conditions Cymbalta is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

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