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Related topic: Cymbalta, Restless legs

Review: could Cymbalta cause Restless legs?

Summary: Restless legs could be caused by Cymbalta, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years, also take Neurontin, and have Depression.

We study 45,418 people who have side effects while taking Cymbalta from FDA and social media. Among them, 317 have Restless legs. Find out below who they are, when they have Restless legs and more.

How are my drugs for patients like me? On eHealthMe, you can find the answer by studying 348 million drug outcomes from FDA and social media. Start now >>>

Cymbalta

Cymbalta (latest outcomes from 48,967 users) has active ingredients of duloxetine hydrochloride. It is often used in depression.

Restless legs

Restless legs (a powerful urge to move your legs) (latest reports from 68,149 patients) has been reported by people with restless leg syndrome, osteoporosis, depression, high blood pressure, pain.

On Apr, 15, 2014: 45,578 people reported to have side effects when taking Cymbalta. Among them, 317 people (0.70%) have Restless Legs. They amount to 0.47% of all the 68,080 people who have Restless Legs on eHealthMe.

Trend of Restless legs in Cymbalta reports

Time on Cymbalta when people have Restless legs * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Restless legs23.94%12.68%9.86%12.68%32.39%7.04%1.41%

Age of people who have Restless legs when taking Cymbalta * :

0-12-910-1920-2930-3940-4950-5960+
Restless legs0.00%0.00%0.80%3.59%14.74%18.33%30.68%31.87%

Severity of Restless legs when taking Cymbalta ** :

leastmoderateseveremost severe
Restless legs0.00%32.00%52.00%16.00%

How people recovered from Restless legs ** :

while on the drugafter off the drugnot yet
Restless legs0.00%22.22%77.78%

Top conditions involved for these people * :

  1. Depression (103 people, 32.49%)
  2. Pain (50 people, 15.77%)
  3. Restless legs syndrome (50 people, 15.77%)
  4. Sleep disorder (39 people, 12.30%)
  5. Muscle spasms (36 people, 11.36%)

Top co-used drugs for these people * :

  1. Neurontin (92 people, 29.02%)
  2. Ambien (81 people, 25.55%)
  3. Lexapro (75 people, 23.66%)
  4. Zometa (62 people, 19.56%)
  5. Prilosec (59 people, 18.61%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

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On eHealthMe, Cymbalta (duloxetine hydrochloride) is often used for depression. Find out below the conditions Cymbalta is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Cymbalta used for and how effective is it:

Other drugs that are used to treat the same conditions:

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Could your condition cause it?

Comments from related studies:

  • From this study (2 months ago):

  • Have been on Gabapentin for years now. For the past 3-4 yrs, I have had a chronically elevated WBC without evidence of illness. WBCs run 10.5 to 13.0 consistently. Even when on antibiotics, has not dropped below 10.5. Am now wondering if this could be related to Gabapentin. The elevated WBCs have resulted in delay of care for back pain issues. At one time, I tried to get off of gabapentin - was titrating the dose(c my provider's permission). I noticed that the Restless Leg Syndrome that I had been experiencing had disappeared with the lower dose of Gabapentin. Unfortunately, the Meralgia Paresthetica synotoms increased & had to increase the Gabapentin back up. RLS came back with increased dose.

    Reply

  • From this study (2 months ago):

  • Have been on Gabapentin for years now. For the past 3-4 yrs, I have had a chronically elevated WBC without evidence of illness.WBCs run 10.5 tp 13.0 consistanly. Even when on antibiotics, has not dropped below 10.5. Am now wondering if this could be related to Gabapentin. The elevated WBCs have resulted in delay of care for back pain issues. At one time, I tried to get off of gabapentin - was titrating the dose(c my provider's permission). I noticed that the Restless Leg Syndrome that I had been experiencing had disappeared with the lower dose of Gabapentin. Unfortunately, the Meralgia Paresthetica synotoms increase & had to increase the Gabapentin back up. RLS came back with increased dose.

    Reply

  • From this study (3 months ago):

  • I have been told and read in the instructions given by the pharmacy that restless legs can be a side effect of Cymbalta. Cymbalta works great for my neuropathy and depression, but the restless legs every night for a couple of hours is bad.

    Reply

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