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Review: could Depakote cause Ataxia?

Summary: Ataxia could be caused by Depakote, especially for people who are female, 50-59 old, have been taking the drug for < 1 month, also take Depakote er, and have Bipolar disorder.

We study 29,548 people who have side effects while taking Depakote from FDA and social media. Among them, 125 have Ataxia. Find out below who they are, when they have Ataxia and more.

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Depakote

Depakote (latest outcomes from 30,866 users) has active ingredients of divalproex sodium. It is often used in bipolar disorder, epilepsy. Commonly reported side effects of Depakote include weight increased, convulsion prophylaxis, convulsion, fatigue, diabetes.

Ataxia

Ataxia (loss of full control of bodily movements) (latest reports from 43,335 patients) has been reported by people with multiple sclerosis, depression, epilepsy, high blood pressure, convulsion.

On Apr, 11, 2014: 29,405 people reported to have side effects when taking Depakote. Among them, 196 people (0.67%) have Ataxia. They amount to 0.46% of all the 42,986 people who have Ataxia on eHealthMe.

Trend of Ataxia in Depakote reports

Time on Depakote when people have Ataxia * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Ataxia40.00%8.00%12.00%12.00%24.00%4.00%0.00%

Gender of people who have Ataxia when taking Depakote * :

FemaleMale
Ataxia53.12%46.88%

Age of people who have Ataxia when taking Depakote * :

0-12-910-1920-2930-3940-4950-5960+
Ataxia0.00%5.88%6.95%4.28%5.88%27.27%34.22%15.51%

Severity of Ataxia when taking Depakote ** :

leastmoderateseveremost severe
Ataxia0.00%100.00%0.00%0.00%

How people recovered from Ataxia ** :

while on the drugafter off the drugnot yet
Ataxia0.00%0.00%100.00%

Top conditions involved for these people * :

  1. Bipolar disorder (28 people, 14.29%)
  2. Convulsion (18 people, 9.18%)
  3. Multiple sclerosis (11 people, 5.61%)
  4. Headache (10 people, 5.10%)
  5. Muscle spasms (8 people, 4.08%)

Top co-used drugs for these people * :

  1. Depakote er (29 people, 14.80%)
  2. Zoloft (25 people, 12.76%)
  3. Atenolol (25 people, 12.76%)
  4. Klonopin (22 people, 11.22%)
  5. Lamictal (22 people, 11.22%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Depakote, Ataxia

You can also:

On eHealthMe, Depakote (divalproex sodium) is often used for bipolar disorder. Find out below the conditions Depakote is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Depakote used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (1 day ago):

  • rick on Apr, 17, 2014:

    You and the other 41 men who participated in this study are all wrong. All of you. All of those side effects are from dapakote alone. Not marijuana. Actually marijuana will help you alleviate the dapakote side effects. Most of them except fatigue and hair loss.
    Personally I think they make dapakote out of super concentrated weed. Feels the same!

    Reply

  • From this study (3 days ago):

  • After doubling my Depakote dose, my abdomen is swollen and I am so dizzy and hallucinating so badly I can barely read. My nausea and pain are so severe, very effective drugs at doses that are a significant amount to my system are barely helping. Due to the weather and thus swelling of my previous Chiai Malformation Decompression Brain Surgery site, I have significant and debilitating headache pain and other Chiari symptoms are much worse than usual.

    Reply

  • From this study (1 week ago):

  • Excessive eye blinking just started two days ago.

    Reply

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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