Depakote and Autism - from FDA reports


Summary

Autism is found among people who take Depakote, especially for people who are male, 2-9 old , have been taking the drug for 10+ years, also take medication Paxil, and have Depression. This review analyzes which people have Autism with Depakote. It is created by eHealthMe based on reports of 38,095 people who have side effects when taking Depakote from FDA, and is updated regularly.

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On Apr, 10, 2017

38,095 people reported to have side effects when taking Depakote.
Among them, 75 people (0.2%) have Autism


Number of reports submitted per year:

Could Depakote cause Autism?

Time on Depakote when people have Autism *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 18.18 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 81.82 %

Gender of people who have Autism when taking Depakote *:

  • female: 27.27 %
  • male: 72.73 %

Age of people who have Autism when taking Depakote *:

  • 0-1: 0.0 %
  • 2-9: 56.25 %
  • 10-19: 37.5 %
  • 20-29: 6.25 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

Top conditions involved for these people *:

  • Depression (13 people, 17.33%)
  • Epilepsy (6 people, 8.00%)
  • Abnormal Behavior (4 people, 5.33%)
  • Stress And Anxiety (3 people, 4.00%)
  • Seizures (3 people, 4.00%)

Top co-used drugs for these people *:

  • Paxil (13 people, 17.33%)
  • Terbutaline Sulfate (8 people, 10.67%)
  • Seroquel (8 people, 10.67%)
  • Serax (6 people, 8.00%)
  • Anafranil (6 people, 8.00%)

Top other side effects for these people *:

  • Developmental Delay (38 people, 50.67%)
  • Foetal Exposure During Pregnancy (34 people, 45.33%)
  • Anhedonia (31 people, 41.33%)
  • Pain (30 people, 40.00%)
  • Abnormal Behavior (29 people, 38.67%)

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Autism when taking Depakote?

Depakote

Depakote has active ingredients of divalproex sodium. It is often used in bipolar disorder. (latest outcomes from Depakote 40,569 users)

Autism

Autism (a mental condition, present from early childhood, characterized by difficulty in communicating and forming relationships with other people and in using language and abstract concepts) has been reported by people with depression, stress and anxiety, epilepsy, drug exposure during pregnancy, attention deficit hyperactivity disorder (latest reports from 3,434 Autism patients).

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