Depakote and Depression - from FDA reports


Summary

Depression is found among people who take Depakote, especially for people who are female, 40-49 old , have been taking the drug for 1 - 6 months, also take medication Seroquel, and have Bipolar disorder . We study 36,649 people who have side effects while taking Depakote from FDA. Among them, 1,348 have Depression. Find out below who they are, when they have Depression and more.

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Depakote

Depakote has active ingredients of divalproex sodium. It is often used in bipolar disorder. (latest outcomes from Depakote 39,085 users)

Depression

Depression has been reported by people with depression, multiple sclerosis, quit smoking, pain (latest reports from 365,256 Depression patients).

On Feb, 13, 2017

36,649 people reported to have side effects when taking Depakote.
Among them, 1,348 people (3.68%) have Depression


Number of reports submitted per year:

Could Depakote cause Depression?

Time on Depakote when people have Depression *:

  • < 1 month: 23.08 %
  • 1 - 6 months: 34.19 %
  • 6 - 12 months: 3.42 %
  • 1 - 2 years: 4.27 %
  • 2 - 5 years: 23.08 %
  • 5 - 10 years: 8.55 %
  • 10+ years: 3.42 %

Gender of people who have Depression when taking Depakote *:

  • female: 59.47 %
  • male: 40.53 %

Age of people who have Depression when taking Depakote *:

  • 0-1: 0.3 %
  • 2-9: 1.0 %
  • 10-19: 9.31 %
  • 20-29: 9.51 %
  • 30-39: 16.62 %
  • 40-49: 24.42 %
  • 50-59: 23.72 %
  • 60+: 15.12 %

Top conditions involved for these people *:

  • Bipolar Disorder (311 people, 23.07%)
  • Pain (152 people, 11.28%)
  • Stress And Anxiety (129 people, 9.57%)
  • Quit Smoking (110 people, 8.16%)
  • Sleep Disorder (75 people, 5.56%)

Top co-used drugs for these people *:

  • Seroquel (301 people, 22.33%)
  • Zyprexa (205 people, 15.21%)
  • Risperdal (181 people, 13.43%)
  • Xanax (165 people, 12.24%)
  • Klonopin (165 people, 12.24%)

Top other side effects for these people *:

  • Stress And Anxiety (423 people, 31.38%)
  • Suicidal Ideation (310 people, 23.00%)
  • Insomnia (271 people, 20.10%)
  • Fatigue (213 people, 15.80%)
  • Headache (203 people, 15.06%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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