Depakote and Drug level increased - from FDA reports


Summary

Drug level increased is found among people who take Depakote, especially for people who are female, 50-59 old , have been taking the drug for < 1 month, also take medication Zyprexa, and have Bipolar disorder. This review analyzes which people have Drug level increased with Depakote. It is created by eHealthMe based on reports of 38,095 people who have side effects when taking Depakote from FDA, and is updated regularly.

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On May, 09, 2017

38,095 people reported to have side effects when taking Depakote.
Among them, 212 people (0.56%) have Drug Level Increased


Number of reports submitted per year:

Could Depakote cause Drug level increased?

Time on Depakote when people have Drug Level Increased *:

  • < 1 month: 35.9 %
  • 1 - 6 months: 25.64 %
  • 6 - 12 months: 12.82 %
  • 1 - 2 years: 12.82 %
  • 2 - 5 years: 10.26 %
  • 5 - 10 years: 2.56 %
  • 10+ years: 0.0 %

Gender of people who have Drug Level Increased when taking Depakote *:

  • female: 50.78 %
  • male: 49.22 %

Age of people who have Drug Level Increased when taking Depakote *:

  • 0-1: 0.0 %
  • 2-9: 6.85 %
  • 10-19: 12.33 %
  • 20-29: 15.75 %
  • 30-39: 12.33 %
  • 40-49: 14.38 %
  • 50-59: 28.77 %
  • 60+: 9.59 %

Top conditions involved for these people *:

  • Bipolar Disorder (48 people, 22.64%)
  • Convulsion (25 people, 11.79%)
  • Schizophrenia (15 people, 7.08%)
  • Epilepsy (12 people, 5.66%)
  • Schizoaffective Disorder (9 people, 4.25%)

Top co-used drugs for these people *:

  • Zyprexa (19 people, 8.96%)
  • Cogentin (15 people, 7.08%)
  • Clozapine (15 people, 7.08%)
  • Clonazepam (13 people, 6.13%)
  • Lamictal (12 people, 5.66%)

Top other side effects for these people *:

  • Convulsion (33 people, 15.57%)
  • Arrhythmias (26 people, 12.26%)
  • Tremor (20 people, 9.43%)
  • Weakness (19 people, 8.96%)
  • Loss Of Consciousness (19 people, 8.96%)

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Drug level increased when taking Depakote?

Depakote

Depakote has active ingredients of divalproex sodium. It is often used in bipolar disorder. (latest outcomes from Depakote 40,584 users)

Drug Level Increased

Drug level increased has been reported by people with schizophrenia, depression, high blood pressure, epilepsy, convulsion (latest reports from 8,651 Drug level increased patients).

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Drugs that are associated with Drug level increased

Drug level increased

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Drug level increased

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What would happen?

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