Depakote and Drug level increased - from FDA reports


Summary

Drug level increased is found among people who take Depakote, especially for people who are female, 50-59 old , have been taking the drug for < 1 month, also take medication Zyprexa, and have Bipolar disorder . We study 36,649 people who have side effects while taking Depakote from FDA. Among them, 204 have Drug level increased. Find out below who they are, when they have Drug level increased and more.

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Depakote

Depakote has active ingredients of divalproex sodium. It is often used in bipolar disorder. (latest outcomes from Depakote 39,089 users)

Drug Level Increased

Drug level increased has been reported by people with schizophrenia, depression, high blood pressure, epilepsy, convulsion (latest reports from 8,299 Drug level increased patients).

On Feb, 13, 2017

36,649 people reported to have side effects when taking Depakote.
Among them, 204 people (0.56%) have Drug Level Increased


Number of reports submitted per year:

Could Depakote cause Drug level increased?

Time on Depakote when people have Drug Level Increased *:

  • < 1 month: 36.84 %
  • 1 - 6 months: 18.42 %
  • 6 - 12 months: 13.16 %
  • 1 - 2 years: 15.79 %
  • 2 - 5 years: 13.16 %
  • 5 - 10 years: 2.63 %
  • 10+ years: 0.0 %

Gender of people who have Drug Level Increased when taking Depakote *:

  • female: 50.81 %
  • male: 49.19 %

Age of people who have Drug Level Increased when taking Depakote *:

  • 0-1: 0.0 %
  • 2-9: 5.67 %
  • 10-19: 12.77 %
  • 20-29: 14.89 %
  • 30-39: 12.77 %
  • 40-49: 14.89 %
  • 50-59: 29.08 %
  • 60+: 9.93 %

Top conditions involved for these people *:

  • Bipolar Disorder (47 people, 23.04%)
  • Convulsion (25 people, 12.25%)
  • Schizophrenia (15 people, 7.35%)
  • Epilepsy (9 people, 4.41%)
  • Hallucinations (8 people, 3.92%)

Top co-used drugs for these people *:

  • Zyprexa (19 people, 9.31%)
  • Cogentin (15 people, 7.35%)
  • Clozapine (15 people, 7.35%)
  • Clonazepam (13 people, 6.37%)
  • Celexa (12 people, 5.88%)

Top other side effects for these people *:

  • Convulsion (33 people, 16.18%)
  • Arrhythmias (26 people, 12.75%)
  • Tremor (20 people, 9.80%)
  • Loss Of Consciousness (19 people, 9.31%)
  • Nausea And Vomiting (18 people, 8.82%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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