Could Depakote cause Ms - from FDA reports


Summary

Ms is found among people who take Depakote, especially for people who are female, 40-49 old , have been taking the drug for < 1 month, also take medication Avonex, and have Pain . We study 36,649 people who have side effects while taking Depakote from FDA. Among them, 133 have Ms. Find out below who they are, when they have Ms and more.

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Depakote

Depakote has active ingredients of divalproex sodium. It is often used in bipolar disorder. (latest outcomes from Depakote 39,070 users)

Ms

Ms has been reported by people with multiple sclerosis, relapsing-remitting multiple sclerosis, depression, pain, gait disturbance (latest reports from 423,506 Ms patients).

On Dec, 27, 2016

36,649 people reported to have side effects when taking Depakote.
Among them, 133 people (0.36%) have Ms


Number of reports submitted per year:

Could Depakote cause Ms?

Time on Depakote when people have Ms *:

  • < 1 month: 75 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 25 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Ms when taking Depakote *:

  • female: 73.48 %
  • male: 26.52 %

Age of people who have Ms when taking Depakote *:

  • 0-1: 0.0 %
  • 2-9: 6.84 %
  • 10-19: 4.27 %
  • 20-29: 4.27 %
  • 30-39: 19.66 %
  • 40-49: 35.9 %
  • 50-59: 18.8 %
  • 60+: 10.26 %

Top conditions involved for these people *:

  • Pain (17 people, 12.78%)
  • Convulsion (15 people, 11.28%)
  • Oedema (11 people, 8.27%)
  • Hypomania (11 people, 8.27%)
  • Depression (11 people, 8.27%)

Top co-used drugs for these people *:

  • Avonex (35 people, 26.32%)
  • Neurontin (32 people, 24.06%)
  • Tegretol (21 people, 15.79%)
  • Betaseron (21 people, 15.79%)
  • Rebif (19 people, 14.29%)

Top other side effects for these people *:

  • Depression (23 people, 17.29%)
  • Pain (22 people, 16.54%)
  • Pain In Extremity (21 people, 15.79%)
  • Weakness (20 people, 15.04%)
  • Insomnia (20 people, 15.04%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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