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Review: could Depakote cause Multiple sclerosis?

We study 29,577 people who have side effects while taking Depakote from FDA and social media. Among them, 111 have Multiple sclerosis. Find out below who they are, when they have Multiple sclerosis and more.

Stay connected: join a mobile support group for people who take Depakote and have Multiple sclerosis >>>

Depakote

Depakote (latest outcomes from 30,897 users) has active ingredients of divalproex sodium. It is often used in bipolar disorder.

Multiple sclerosis

Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath) (latest reports from 280,269 patients) has been reported by people with relapsing-remitting multiple sclerosis, depression, pain, high blood pressure, rheumatoid arthritis.

On Jul, 22, 2014: 29,577 people reported to have side effects when taking Depakote. Among them, 130 people (0.44%) have Multiple Sclerosis. They amount to 0.05% of all the 280,269 people who have Multiple Sclerosis on eHealthMe.

Trend of Multiple sclerosis in Depakote reports

Time on Depakote when people have Multiple sclerosis * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Multiple sclerosis100.00%0.00%0.00%0.00%0.00%0.00%0.00%

Gender of people who have Multiple sclerosis when taking Depakote * :

FemaleMale
Multiple sclerosis75.45%24.55%

Age of people who have Multiple sclerosis when taking Depakote * :

0-12-910-1920-2930-3940-4950-5960+
Multiple sclerosis0.00%5.62%3.75%5.00%16.88%36.25%26.88%5.62%

Severity of Multiple sclerosis when taking Depakote ** :

n/a

How people recovered from Multiple sclerosis ** :

n/a

Top conditions involved for these people * :

  1. Multiple sclerosis (86 people, 66.15%)
  2. Pain (18 people, 13.85%)
  3. Convulsion (14 people, 10.77%)
  4. Petit mal epilepsy (12 people, 9.23%)
  5. Oedema (10 people, 7.69%)

Top co-used drugs for these people * :

  1. Avonex (64 people, 49.23%)
  2. Neurontin (33 people, 25.38%)
  3. Rebif (28 people, 21.54%)
  4. Betaseron (26 people, 20.00%)
  5. Baclofen (23 people, 17.69%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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Comments from related studies:

  • From this study (5 days ago):

  • Leg/left weakness and gives out
    Degenerative disc disease
    L1 S5 herniation/bulging
    Numbness tingling loss of use and feeling left leg
    Severe pain

    Reply

  • From this study (5 days ago):

  • I was on a combination of Depakote ER, Birth control, and Prednisone and gained 40lbs in a matter of two months. I went from being a normal weight of 125 at 5'3" to 165 plus. The symptom that was the worst was that my size C breasts went from that to a DD and now a DDD. It is very uncomfortable and I have back problems so that does not help.
    I found info at one time that said the birth control tricks your body into thinking it is pregnant and then the Depakote ER expands your breasts in a reaction of the two meds. I need to know if one of these or two or all of these meds induced my larger breasts. Thank you!

    Reply

  • From this study (3 weeks ago):

  • Constant movement
    Jaw movement side to side and a hard bite (can hear teeth hit each other) every 20 min or so.

    Reply

Post a new comment    OR    Read more comments

Can you answer these questions (what is this?):

More questions for: Depakote, Multiple sclerosis

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  • Developed systemic scleroderma while on copaxone for 10 yrs.
    I just tested positive for both crest and systemic scleroderma. I already have ms and have been on copaxone over 10 yrs. I believe copaxone may have caused this. I dont blame the makers. I am sure it has helped more then hurt, but I wonder if this has happened to others. If so it should be something ...

  • Depakote er affected by grapefruit
    I have taken Depakote ER for since 2005 for epilepsy. Once stabilized many years ago seizures and auras have not been bothering me. Until I recently ate three grapefruits over three days. After a few days, when the grapefruit cleared my system, the seizures and auras ceased. Therefore, grapefrui ...

  • Topamax for weight loss, causing diarrhea
    I was taking Topamax for weight loss and it worked very well. After 2 months I started having diarrhea. I stopped Topamax and the diarrhea stopped. Is there any drug or supplement I can take Topamax that will stop the diarrhea?

More reviews for: Depakote, Multiple sclerosis

On eHealthMe, Depakote (divalproex sodium) is often used for bipolar disorder. Find out below the conditions Depakote is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Depakote used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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