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Review: could Depakote cause Multiple sclerosis?

Summary: Multiple sclerosis could be caused by Depakote, especially for people who are female, 40-49 old, have been taking the drug for < 1 month, also take Avonex, and have Multiple sclerosis.

We study 29,548 people who have side effects while taking Depakote from FDA and social media. Among them, 130 have Multiple sclerosis. Find out below who they are, when they have Multiple sclerosis and more.

On Apr, 16, 2014: 29,548 people reported to have side effects when taking Depakote. Among them, 130 people (0.44%) have Multiple Sclerosis. They amount to 0.05% of all the 279,935 people who have Multiple Sclerosis on eHealthMe.

Trend of Multiple sclerosis in Depakote reports

Time on Depakote when people have Multiple sclerosis * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Multiple sclerosis100.00%0.00%0.00%0.00%0.00%0.00%0.00%

Gender of people who have Multiple sclerosis when taking Depakote * :

FemaleMale
Multiple sclerosis75.45%24.55%

Age of people who have Multiple sclerosis when taking Depakote * :

0-12-910-1920-2930-3940-4950-5960+
Multiple sclerosis0.00%5.62%3.75%5.00%16.88%36.25%26.88%5.62%

Severity of Multiple sclerosis when taking Depakote ** :

n/a

How people recovered from Multiple sclerosis ** :

n/a

Top conditions involved for these people * :

  1. Multiple sclerosis (86 people, 66.15%)
  2. Pain (18 people, 13.85%)
  3. Convulsion (14 people, 10.77%)
  4. Petit mal epilepsy (12 people, 9.23%)
  5. Oedema (10 people, 7.69%)

Top co-used drugs for these people * :

  1. Avonex (64 people, 49.23%)
  2. Neurontin (33 people, 25.38%)
  3. Rebif (28 people, 21.54%)
  4. Betaseron (26 people, 20.00%)
  5. Baclofen (23 people, 17.69%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Depakote, Multiple sclerosis

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On eHealthMe, Depakote (divalproex sodium) is often used for bipolar disorder. Find out below the conditions Depakote is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Depakote used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (2 hours ago):

  • rick on Apr, 17, 2014:

    You and the other 41 men who participated in this study are all wrong. All of you. All of those side effects are from dapakote alone. Not marijuana. Actually marijuana will help you alleviate the dapakote side effects. Most of them except fatigue and hair loss.
    Personally I think they make dapakote out of super concentrated weed. Feels the same!

    Reply

  • From this study (2 days ago):

  • After doubling my Depakote dose, my abdomen is swollen and I am so dizzy and hallucinating so badly I can barely read. My nausea and pain are so severe, very effective drugs at doses that are a significant amount to my system are barely helping. Due to the weather and thus swelling of my previous Chiai Malformation Decompression Brain Surgery site, I have significant and debilitating headache pain and other Chiari symptoms are much worse than usual.

    Reply

  • From this study (6 days ago):

  • Excessive eye blinking just started two days ago.

    Reply

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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