Depakote and Renal failure - from FDA reports


Summary

Renal failure is found among people who take Depakote, especially for people who are male, 60+ old , have been taking the drug for < 1 month, also take medication Seroquel, and have Bipolar disorder . We study 36,649 people who have side effects while taking Depakote from FDA. Among them, 289 have Renal failure. Find out below who they are, when they have Renal failure and more.

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Depakote

Depakote has active ingredients of divalproex sodium. It is often used in bipolar disorder. (latest outcomes from Depakote 39,085 users)

Renal Failure

Renal failure (kidney dysfunction) has been reported by people with high blood pressure, multiple myeloma, coronary artery bypass, diabetes, rheumatoid arthritis (latest reports from 82,171 Renal failure patients).

On Jan, 26, 2017

36,649 people reported to have side effects when taking Depakote.
Among them, 289 people (0.79%) have Renal Failure


Number of reports submitted per year:

Could Depakote cause Renal failure?

Time on Depakote when people have Renal Failure *:

  • < 1 month: 48.39 %
  • 1 - 6 months: 22.58 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 19.35 %
  • 2 - 5 years: 3.23 %
  • 5 - 10 years: 6.45 %
  • 10+ years: 0.0 %

Gender of people who have Renal Failure when taking Depakote *:

  • female: 45.39 %
  • male: 54.61 %

Age of people who have Renal Failure when taking Depakote *:

  • 0-1: 0.44 %
  • 2-9: 0.44 %
  • 10-19: 0.88 %
  • 20-29: 4.39 %
  • 30-39: 13.6 %
  • 40-49: 25.44 %
  • 50-59: 23.68 %
  • 60+: 31.14 %

Top conditions involved for these people *:

  • Bipolar Disorder (57 people, 19.72%)
  • Depression (43 people, 14.88%)
  • Schizophrenia (31 people, 10.73%)
  • High Blood Cholesterol (26 people, 9.00%)
  • Sleep Disorder (23 people, 7.96%)

Top co-used drugs for these people *:

  • Seroquel (82 people, 28.37%)
  • Zyprexa (66 people, 22.84%)
  • Risperdal (57 people, 19.72%)
  • Abilify (43 people, 14.88%)
  • Ambien (35 people, 12.11%)

Top other side effects for these people *:

  • Diabetes (53 people, 18.34%)
  • Type 2 Diabetes (47 people, 16.26%)
  • High Blood Cholesterol (38 people, 13.15%)
  • Fatigue (36 people, 12.46%)
  • Dehydration (35 people, 12.11%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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