Could Depakote cause Sleeplessness - from FDA reports


Summary

Sleeplessness is found among people who take Depakote, especially for people who are female, 50-59 old , have been taking the drug for 2 - 5 years, also take medication Seroquel, and have Bipolar disorder . We study 33,936 people who have side effects while taking Depakote from FDA. Among them, 1,144 have Sleeplessness. Find out below who they are, when they have Sleeplessness and more.

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Depakote

Depakote has active ingredients of divalproex sodium. It is often used in bipolar disorder. (latest outcomes from Depakote 39,050 users)

Sleeplessness

Sleeplessness (a sleep disorder in which there is an inability to fall asleep or to stay asleep as long as desired) has been reported by people with depression, multiple sclerosis, pain, insomnia (latest reports from 206,791 Sleeplessness patients).

On Nov, 19, 2016

33,936 people reported to have side effects when taking Depakote.
Among them, 1,144 people (3.37%) have Sleeplessness


Number of reports submitted per year:

Could Depakote cause Sleeplessness?

Time on Depakote when people have Sleeplessness *:

  • < 1 month: 21.84 %
  • 1 - 6 months: 12.64 %
  • 6 - 12 months: 8.05 %
  • 1 - 2 years: 10.34 %
  • 2 - 5 years: 29.89 %
  • 5 - 10 years: 5.75 %
  • 10+ years: 11.49 %

Gender of people who have Sleeplessness when taking Depakote *:

  • female: 60.58 %
  • male: 39.42 %

Age of people who have Sleeplessness when taking Depakote *:

  • 0-1: 0.56 %
  • 2-9: 2.58 %
  • 10-19: 6.72 %
  • 20-29: 9.97 %
  • 30-39: 17.58 %
  • 40-49: 23.74 %
  • 50-59: 24.41 %
  • 60+: 14.45 %

Severity of Sleeplessness **:

  • least: 9.09 %
  • moderate: 36.36 %
  • severe: 54.55 %
  • most severe: 0.0 %

Top co-used drugs for these people *:

  • Seroquel (320 people, 27.97%)
  • Zyprexa (186 people, 16.26%)
  • Xanax (147 people, 12.85%)
  • Risperdal (134 people, 11.71%)
  • Paxil (129 people, 11.28%)

Forecasts by ePatient.care (We will alert you to new symptoms or undetected conditions when you take Depakote, learn more )

Potential co-existing conditions

  • Pain (98 people, 8.57%)
  • Sleep Disorder (88 people, 7.69%)

Potential co-existing symptoms

  • Stress And Anxiety (295 people, 25.79%)
  • Depression (250 people, 21.85%)
  • Headache (242 people, 21.15%)
  • Fatigue (214 people, 18.71%)
  • Agitation (191 people, 16.70%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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