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Related topic: Depakote, Splenomegaly

Review: could Depakote cause Splenomegaly?

Summary: Splenomegaly could be caused by Depakote, especially for people who are female, 50-59 old, have been taking the drug for 1 - 6 months, also take Ativan, and have Hiv infection.

We study 29,548 people who have side effects while taking Depakote from FDA and social media. Among them, 56 have Splenomegaly. Find out below who they are, when they have Splenomegaly and more.

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Depakote

Depakote (latest outcomes from 30,866 users) has active ingredients of divalproex sodium. It is often used in bipolar disorder.

Splenomegaly

Splenomegaly (enlargement of spleen) (latest reports from 38,946 patients) has been reported by people with rheumatoid arthritis, hiv infection, high blood pressure, hepatitis c, multiple sclerosis.

On Apr, 12, 2014: 29,405 people reported to have side effects when taking Depakote. Among them, 56 people (0.19%) have Splenomegaly. They amount to 0.14% of all the 38,868 people who have Splenomegaly on eHealthMe.

Trend of Splenomegaly in Depakote reports

Time on Depakote when people have Splenomegaly * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Splenomegaly0.00%66.67%0.00%0.00%33.33%0.00%0.00%

Gender of people who have Splenomegaly when taking Depakote * :

FemaleMale
Splenomegaly51.67%48.33%

Age of people who have Splenomegaly when taking Depakote * :

0-12-910-1920-2930-3940-4950-5960+
Splenomegaly0.00%0.00%7.55%16.98%9.43%26.42%37.74%1.89%

Severity of Splenomegaly when taking Depakote ** :

n/a

How people recovered from Splenomegaly ** :

n/a

Top conditions involved for these people * :

  1. Hiv infection (5 people, 8.93%)
  2. Sleep disorder (5 people, 8.93%)
  3. Ill-defined disorder (3 people, 5.36%)
  4. Agitation (3 people, 5.36%)
  5. Bipolar i disorder (2 people, 3.57%)

Top co-used drugs for these people * :

  1. Ativan (20 people, 35.71%)
  2. Xanax (17 people, 30.36%)
  3. Lasix (13 people, 23.21%)
  4. Clonidine (12 people, 21.43%)
  5. Protonix (12 people, 21.43%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Depakote (divalproex sodium) is often used for bipolar disorder. Find out below the conditions Depakote is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Depakote used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (1 day ago):

  • We have been trying to have a baby for 2 yrs. My wife got pregnant before Christmas and miss carried at 9 weeks. I was on 1000 mg of depakote daily for 2 yrs. Have been off for 4 months now

    Reply

  • From this study (6 days ago):

  • rick on Apr, 17, 2014:

    You and the other 41 men who participated in this study are all wrong. All of you. All of those side effects are from dapakote alone. Not marijuana. Actually marijuana will help you alleviate the dapakote side effects. Most of them except fatigue and hair loss.
    Personally I think they make dapakote out of super concentrated weed. Feels the same!

    Reply

  • From this study (1 week ago):

  • After doubling my Depakote dose, my abdomen is swollen and I am so dizzy and hallucinating so badly I can barely read. My nausea and pain are so severe, very effective drugs at doses that are a significant amount to my system are barely helping. Due to the weather and thus swelling of my previous Chiai Malformation Decompression Brain Surgery site, I have significant and debilitating headache pain and other Chiari symptoms are much worse than usual.

    Reply

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