Depakote and Splenomegaly - from FDA reports


Summary

Splenomegaly is found among people who take Depakote, especially for people who are male, 50-59 old , have been taking the drug for 1 - 6 months, also take medication Ativan, and have Hiv infection. This review analyzes which people have Splenomegaly with Depakote. It is created by eHealthMe based on reports of 38,095 people who have side effects when taking Depakote from FDA, and is updated regularly.

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On Apr, 19, 2017

38,095 people reported to have side effects when taking Depakote.
Among them, 61 people (0.16%) have Splenomegaly


Number of reports submitted per year:

Could Depakote cause Splenomegaly?

Time on Depakote when people have Splenomegaly *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 66.67 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 16.67 %
  • 5 - 10 years: 16.67 %
  • 10+ years: 0.0 %

Gender of people who have Splenomegaly when taking Depakote *:

  • female: 48.33 %
  • male: 51.67 %

Age of people who have Splenomegaly when taking Depakote *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 7.69 %
  • 20-29: 17.31 %
  • 30-39: 13.46 %
  • 40-49: 25.0 %
  • 50-59: 34.62 %
  • 60+: 1.92 %

Top conditions involved for these people *:

  • Hiv Infection (5 people, 8.20%)
  • Sleep Disorder (3 people, 4.92%)
  • Ill-Defined Disorder (3 people, 4.92%)
  • Agitation (3 people, 4.92%)
  • Bipolar I Disorder (2 people, 3.28%)

Top co-used drugs for these people *:

  • Ativan (21 people, 34.43%)
  • Xanax (19 people, 31.15%)
  • Lisinopril (14 people, 22.95%)
  • Clonidine (14 people, 22.95%)
  • Lasix (13 people, 21.31%)

Top other side effects for these people *:

  • Thrombocytopenia (25 people, 40.98%)
  • Pleural Effusion (18 people, 29.51%)
  • High Blood Pressure (18 people, 29.51%)
  • Anaemia (17 people, 27.87%)
  • Pancytopenia (16 people, 26.23%)

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Splenomegaly when taking Depakote?

Depakote

Depakote has active ingredients of divalproex sodium. It is often used in bipolar disorder. (latest outcomes from Depakote 40,584 users)

Splenomegaly

Splenomegaly (enlargement of spleen) has been reported by people with primary myelofibrosis, rheumatoid arthritis, chronic myeloid leukaemia, hiv infection, high blood pressure (latest reports from 8,766 Splenomegaly patients).

Browse all side effects of Depakote

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Drugs that are associated with Splenomegaly

Splenomegaly

Could your condition cause Splenomegaly

Splenomegaly

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What would happen?

Forecast new side effects and undetected conditions when you take Depakote and have Splenomegaly.

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