Could Depakote cause Splenomegaly - from FDA reports


Summary

Splenomegaly is found among people who take Depakote, especially for people who are male, 50-59 old , have been taking the drug for 1 - 6 months, also take medication Ativan, and have Hiv infection . We study 36,649 people who have side effects while taking Depakote from FDA. Among them, 61 have Splenomegaly. Find out below who they are, when they have Splenomegaly and more.

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Depakote

Depakote has active ingredients of divalproex sodium. It is often used in bipolar disorder. (latest outcomes from Depakote 39,050 users)

Splenomegaly

Splenomegaly (enlargement of spleen) has been reported by people with primary myelofibrosis, rheumatoid arthritis, chronic myeloid leukaemia, hiv infection, high blood pressure (latest reports from 8,363 Splenomegaly patients).

On Dec, 05, 2016

36,649 people reported to have side effects when taking Depakote.
Among them, 61 people (0.17%) have Splenomegaly


Number of reports submitted per year:

Could Depakote cause Splenomegaly?

Time on Depakote when people have Splenomegaly *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 66.67 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 16.67 %
  • 5 - 10 years: 16.67 %
  • 10+ years: 0.0 %

Gender of people who have Splenomegaly when taking Depakote *:

  • female: 48.33 %
  • male: 51.67 %

Age of people who have Splenomegaly when taking Depakote *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 7.69 %
  • 20-29: 17.31 %
  • 30-39: 13.46 %
  • 40-49: 25.0 %
  • 50-59: 34.62 %
  • 60+: 1.92 %

Top co-used drugs for these people *:

  • Ativan (21 people, 34.43%)
  • Xanax (19 people, 31.15%)
  • Lisinopril (14 people, 22.95%)
  • Clonidine (14 people, 22.95%)
  • Lasix (13 people, 21.31%)

Forecasts by ePatient.care (We will alert you to new symptoms or undetected conditions when you take Depakote, learn more )

Potential co-existing conditions

  • Hiv Infection (5 people, 8.20%)

Potential co-existing symptoms

  • Thrombocytopenia (25 people, 40.98%)
  • Pleural Effusion (18 people, 29.51%)
  • High Blood Pressure (18 people, 29.51%)
  • Anaemia (17 people, 27.87%)
  • Pancytopenia (16 people, 26.23%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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