Could Depakote cause Splenomegaly - from FDA reports
Splenomegaly is found among people who take Depakote, especially for people who are male, 50-59 old , have been taking the drug for 1 - 6 months, also take medication Ativan, and have Hiv infection . We study 36,649 people who have side effects while taking Depakote from FDA. Among them, 61 have Splenomegaly. Find out below who they are, when they have Splenomegaly and more.
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Depakote has active ingredients of divalproex sodium. It is often used in bipolar disorder. (latest outcomes from Depakote 39,075 users)
Splenomegaly (enlargement of spleen) has been reported by people with primary myelofibrosis, rheumatoid arthritis, chronic myeloid leukaemia, hiv infection, high blood pressure (latest reports from 8,364 Splenomegaly patients).
On Jan, 13, 2017
36,649 people reported to have side effects when taking Depakote.
Among them, 61 people (0.17%) have Splenomegaly
Number of reports submitted per year:
Time on Depakote when people have Splenomegaly *:
- < 1 month: 0.0 %
- 1 - 6 months: 66.67 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 16.67 %
- 5 - 10 years: 16.67 %
- 10+ years: 0.0 %
Gender of people who have Splenomegaly when taking Depakote *:
- female: 48.33 %
- male: 51.67 %
Age of people who have Splenomegaly when taking Depakote *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 7.69 %
- 20-29: 17.31 %
- 30-39: 13.46 %
- 40-49: 25.0 %
- 50-59: 34.62 %
- 60+: 1.92 %
Top conditions involved for these people *:
- Hiv Infection (5 people, 8.20%)
- Sleep Disorder (3 people, 4.92%)
- Ill-Defined Disorder (3 people, 4.92%)
- Agitation (3 people, 4.92%)
- Bipolar I Disorder (2 people, 3.28%)
Top co-used drugs for these people *:
- Ativan (21 people, 34.43%)
- Xanax (19 people, 31.15%)
- Lisinopril (14 people, 22.95%)
- Clonidine (14 people, 22.95%)
- Lasix (13 people, 21.31%)
Top other side effects for these people *:
- Thrombocytopenia (25 people, 40.98%)
- Pleural Effusion (18 people, 29.51%)
- High Blood Pressure (18 people, 29.51%)
- Anaemia (17 people, 27.87%)
- Diarrhea (16 people, 26.23%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
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