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Review: could Depakote cause Substance abuse?

Summary: Substance abuse could be caused by Depakote, especially for people who are male, 40-49 old, have been taking the drug for 1 - 6 months, also take Seroquel, and have Bipolar disorder.

We study 29,548 people who have side effects while taking Depakote from FDA and social media. Among them, 76 have Substance abuse. Find out below who they are, when they have Substance abuse and more.

On Apr, 8, 2014: 29,405 people reported to have side effects when taking Depakote. Among them, 76 people (0.26%) have Substance Abuse. They amount to 0.17% of all the 45,226 people who have Substance Abuse on eHealthMe.

Trend of Substance abuse in Depakote reports

Time on Depakote when people have Substance abuse * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Substance abuse0.00%100.00%0.00%0.00%0.00%0.00%0.00%

Gender of people who have Substance abuse when taking Depakote * :

FemaleMale
Substance abuse43.53%56.47%

Age of people who have Substance abuse when taking Depakote * :

0-12-910-1920-2930-3940-4950-5960+
Substance abuse1.25%2.50%7.50%23.75%25.00%27.50%12.50%0.00%

Severity of Substance abuse when taking Depakote ** :

n/a

How people recovered from Substance abuse ** :

n/a

Top conditions involved for these people * :

  1. Bipolar disorder (28 people, 36.84%)
  2. Depression (24 people, 31.58%)
  3. Anxiety (18 people, 23.68%)
  4. Sleep disorder (12 people, 15.79%)
  5. Schizophrenia (10 people, 13.16%)

Top co-used drugs for these people * :

  1. Seroquel (51 people, 67.11%)
  2. Risperdal (28 people, 36.84%)
  3. Zyprexa (26 people, 34.21%)
  4. Lexapro (24 people, 31.58%)
  5. Klonopin (23 people, 30.26%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Depakote, Substance abuse

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On eHealthMe, Depakote (divalproex sodium) is often used for bipolar disorder. Find out below the conditions Depakote is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Depakote used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (1 day ago):

  • After doubling my Depakote dose, my abdomen is swollen and I am so dizzy and hallucinating so badly I can barely read. My nausea and pain are so severe, very effective drugs at doses that are a significant amount to my system are barely helping. Due to the weather and thus swelling of my previous Chiai Malformation Decompression Brain Surgery site, I have significant and debilitating headache pain and other Chiari symptoms are much worse than usual.

    Reply

  • From this study (5 days ago):

  • Excessive eye blinking just started two days ago.

    Reply

  • From this study (2 weeks ago):

  • frequent urination diabetes insipidus

    Reply

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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