Review: could Depo-provera cause Depression?
Summary: Depression is found among people who take Depo-provera, especially for people who are female, 20-29 old, have been taking the drug for < 1 month, also take medication Accutane, and have Birth control.
We study 9,960 people who have side effects while taking Depo-provera from FDA and social media. Among them, 715 have Depression. Find out below who they are, when they have Depression and more.
You are not alone: join a mobile support group for people who take Depo-provera and have Depression >>>
Depo-provera has active ingredients of medroxyprogesterone acetate. It is often used in birth control. (latest outcomes from 10,378 Depo-provera users)
Depression has been reported by people with quit smoking, multiple sclerosis, pain, osteoporosis, acne. (latest reports from 277,322 Depression patients)
On Feb, 19, 2015: 9,960 people reported to have side effects when taking Depo-provera. Among them, 715 people (7.18%) have Depression.
Time on Depo-provera when people have Depression * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
Age of people who have Depression when taking Depo-provera * :
Severity of Depression when taking Depo-provera ** :
|least||moderate||severe||most severe |
How people recovered from Depression ** :
|while on the drug||after off the drug||not yet |
Top conditions involved for these people * :
- Contraception (232 people, 32.45%)
- Endometriosis (36 people, 5.03%)
- Depression (33 people, 4.62%)
- Blood cholesterol increased (21 people, 2.94%)
- Asthma (20 people, 2.80%)
Top co-used drugs for these people * :
- Accutane (45 people, 6.29%)
- Lexapro (35 people, 4.90%)
- Effexor (35 people, 4.90%)
- Paxil (30 people, 4.20%)
- Seroquel (27 people, 3.78%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
Get connected: join our support group of depo-provera and depression on
Do you have Depression while taking Depo-provera?
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- support group for people who take Depo-provera and have Depression
- support group for people who take Depo-provera
- support group for people who have Depression
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Can you answer these questions (Ask a question):
- I too have hashimoto's and hydrocephalus
I have been HYPOTHYROID since at least 18 years old, now 43, and last 2 years found out that I did test positive for Hashimotos and was told I have no thyroid left. When I was 26, I had visual disturbance and went to the ER. Was told by the neurologist that I had mild hydroencephaly, and may require a shunt. Due to lack of insurance, went years with no treatment or follow up. Now have numerous problems with Hashimotos/Hypothyroid and investigating the correlation between the Hydroencephaly and Hashimotos. Is this the only study of the two relations?
- Is bed wetting part of having syringomyelia
i also use panadol osteo, mintec, apo-meloxicam. i have wetting the bed is was just now and then but it has started to become more frequent now, does any one else had this happen.
- Does provera contain sulfur
I have had my period for 3 weeks now, saw my OBGYN yesterday and was prescribed Provera to stop the bleeding, this is my second day on the medication and am experiencing a migraine. Is their a sulfur base in the compound used for Provera?
- What are the effect of taking amatripline an premarin at the same time
I am on amitriptyline. To help with depression an to help me sleep.do to pain from five surgery.I am on preparing an medroxyprogesterone for hot flashes I only take the medroxyprogesterone ten days a month.
- How do i change the drugs listed for me?
sleep disorders, disorientation, trouble concentrating
More questions for: Depo-provera, Depression
You may be interested at these reviews (Write a review):
- Depo provera and erythema nodosum
I've been suffering from erythema nodosum for 17 years which started within the first year of depo provera use, in 1997. Now at age 43 and 4 kids later, I really wish I'd never taken depo provera.
- Are you mental on methadone
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- Low potasium and mood
While being treated for cancer about 3 years ago and thus taking a number of blood tests, I was diagnosed with low potassium level and prescribed a regular dosage. I had noticed that when I forgot to take my potassium pills, I soon began to feel more depressed than usual and to feel anxious. Taking the ills soon alleviated these symptoms. (I have had depression for most of my life but long ago decided against taking any of the anti-depression Rx pills because I disliked their side effects, especially on my ability to think clearly.) Very recently I finally got around to looking on the Internet to see whether low potassium was associated with mood disorders _ and I found that it was. This site apparently didn't study anyone my age (I'm 78), so I decided to offer these comments. I have at least one grandchild who has been formally diagnosed with depression, and one who is ADHD. Before finding that the relationship of mood and low potassium was formally known, I had suggested to their parent in a low-key way that perhaps she and they should check with their doctors about their potassium levels. Now I'm quite sure that is something they and their doctors should consider. Meanwhile, I am glad to have found formal study of what had been to me only an anecdotal kind of belief that the two were linked. More importantly, in all my years of doctor visits, no doctor and no psychologist has ever mentioned this link to me. Therefore, I hope that somehow this link is brought more to the forefront of medical attention.
- Suboxone treatment may have caused my trichotillomania
It's a long story of how I became addicted to opiates after 15+ years of chronic pain, but I decided to give up pain killers and try suboxone/subutex treatment. Shortly thereafter, I began pulling hair. First from my head, then when the bald spots became too obvious I started pulling from all over. It seemed to be triggered by stress or anxiety but not always. I did not make an association until recently, when I finally stopped the suboxone. It was two weeks of miserable withdrawal, much worse than from pain killers themselves, but I am finally out of the haze I'd be in all of that time, and I have no urge to pull hair whatsoever. I don't know how often the association of suboxone use and trichotillomania has been examined, but I wanted to share my experience in case anyone else is in a similar situation. Also, if you are considering starting suboxone treatment, don't. Withdrawal from opiates will lead to a few pretty rough days, but that's nothing compared to what you'll go through during suboxone withdrawal.
- Librium 25mg and wellbutrin 300mg for >1 month
I've been taking librium twice daily, morning and night, for about 3 months now along with wellbutrin XL in the morning. I've basically had the mood of "I don't care" and a great boost in confidence.
More reviews for: Depo-provera, Depression
Comments from related studies:
From this study (2 years ago):
Carmen on May, 4, 2012:
My experience with Depo has been a nightmare/horror story that seems to never end. I physically look and feel different compared to before my shot. First let me say that I took this shot a few times when I was about 17/18 years old. Didn't 'think' I had any side effects back then.... Had the shot for the first time since then back in September of 2010....NEVER AGAIN! Let me add to the past by saying now with all of the side effects I began experiencing within 2 weeks of that September 2010 shot, I now realize I DID have side effects when I was younger, I just didn't realize it then. My whole life my vision was 20/20 until I was about 18/19/20. My eyes began bothering me, felt blurry all the time, was having alot of headaches. Found out I suddenly had a stigmatism that I never had before. I've had circulation problems all through my 20's. So fast forward....2 weeks after my shot in September of 2010, I began experiencing horrifying hair changes and I began bleeding. It was 'that time of the month' after that every single day through January of 2011. Yes, 4-5 months of bleeding every day!
Carmen on May, 4, 2012:
(The rest of my comment continued from above) My hair? My hair became extremely extremely disgustingly greasy and slowly became thinner and thinner. Before that, my hair was beautiful, thick, naturally curly/wavy. The kind of hair that I could wear curly or straighten with a flat iron. Once I finally realized the cause, I didnt' go back for my second shot! I realized when researching my hair issues....I was HORRIFIED! Also at that time...I had lost all of my pregnancy weight from giving birth to twins just 7 months before this. That August I was teeny tiny. I ate right and exercised all of that pregnancy weight off. My whole life I never ever had problems with my weight. After a baby I would lose the weight if I ate right and exercised. Well, within the first 6 months of depo for me, I gained 10-20 pounds. Ok, so I tried to stop my hair problems. I'm still fighting these problems almost 2 years after that shot. I have some other health issues that I wonder if it could be related to the shots when I was younger. Heart issues, breathing issues, back issues. The back issues just started this past year. Where it's hard for me to sit up straight. Fast forward to now. I've managed to control my hair even though it will never be the same again. I use organic shampoos only, preferably anything with Green Tea. It helps a lot if you have this problem with oily hair which I NEVER had until 2 weeks after that shot in September! My hair texture has also changed like someone else commented. My hair seems stringy and dry now, along with a little bit oily inspite of the organic shampoo that thankfully helps because it could be so much worse! At one point I avoided conditioner for almost a year!
Carmen on May, 4, 2012:
(sorry, there was more to my comment....continued from above...this is it though :) Before this experience my hair was the opposite, I would struggle to tame my mane because it was so thick, etc. As for my weight, I am disgusted. No matter how hard I try, I can't seem to lose this 10-15 pounds. I lost 5 or so but can't get the rest off. I want to vomit when I look at myself. I'm also severely bloated ALLL day no matter how much or little I eat! It seems like I gain weight just from breathing! Mood problems. I already have mood issues, so this shot made them worse. That is pretty much under control now though. Within the past year, I also started having problems with my legs, bad circulation problems through my whole body with veins. Even my arms. But my legs also had bad edema at one point. I take Horsechestnut and it helps my circulation a lot. If I miss a pill my legs ache. My legs were in a lot of pain. My knees started bothering me a lot too, I can feel what my mother says sounds like 'calcium deposits'....a strange noise my knees make. Like a popping noise? when I move them a certain way. Not all the time. I started taking Tums as a calcium supplement recently too. Another thing I do with my hair is I take a prenatal vitamin...it helps with the hair loss problem!!! Helped a lot actually. I feel like I look really old and terrible lately. This didn't start until after the depo. Hopefully I will be able to get back to the old me....my weight and hair make me want to cry sometimes because I'm trying and trying but my hair is just not the same. My belly looks like I'm 3 months pregnant sometimes from the bloating. Doesn't make you feel so pretty.... :(
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