Review: could Depo-provera cause Depression?
Summary: Depression is found among people who take Depo-provera, especially for people who are female, 20-29 old, have been taking the drug for < 1 month, also take medication Accutane, and have Birth control.
We study 9,948 people who have side effects while taking Depo-provera from FDA and social media. Among them, 715 have Depression. Find out below who they are, when they have Depression and more.
You are not alone: join a mobile support group for people who take Depo-provera and have Depression >>>
Depo-provera has active ingredients of medroxyprogesterone acetate. It is often used in birth control. (latest outcomes from 10,364 Depo-provera users)
Depression has been reported by people with quit smoking, multiple sclerosis, pain, osteoporosis, high blood pressure. (latest reports from 276,944 Depression patients)
On Jan, 19, 2015: 9,948 people reported to have side effects when taking Depo-provera. Among them, 715 people (7.19%) have Depression.
Time on Depo-provera when people have Depression * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
Age of people who have Depression when taking Depo-provera * :
Severity of Depression when taking Depo-provera ** :
|least||moderate||severe||most severe |
How people recovered from Depression ** :
|while on the drug||after off the drug||not yet |
Top conditions involved for these people * :
- Contraception (232 people, 32.45%)
- Endometriosis (36 people, 5.03%)
- Depression (33 people, 4.62%)
- Blood cholesterol increased (21 people, 2.94%)
- Asthma (20 people, 2.80%)
Top co-used drugs for these people * :
- Accutane (45 people, 6.29%)
- Lexapro (35 people, 4.90%)
- Effexor (35 people, 4.90%)
- Paxil (30 people, 4.20%)
- Seroquel (27 people, 3.78%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
Do you have Depression while taking Depo-provera?
You are not alone! Join a mobile support group:
- support group for people who take Depo-provera and have Depression
- support group for people who take Depo-provera
- support group for people who have Depression
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sleep disorders, disorientation, trouble concentrating
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I have been on Adderall 30mg 2x daily for years!! I've had it lowered to 20mg, I've TRIED to go months without it (when not working) however I feel I've built up a tolerance level to the point that it's not as effective as it once was. My personal life has detoured WAY past anything an ADHD medication can possibly help as far as focusing on NEEDED tasks etc. I end up feeling wrapped up in what I'm doing at the moment that my anxiety increases due to all that I haven't been able to accomplish. I take various medications for various reasons, depression, anxiety, bulimia etc., and for the most part the doses have varied based on circumstances and current need at said time of prescription.. MY FAMILY HAS A HISTORY OF HEART DISEASE, And realizing that I'm already on the highest Adderall dosage scares me (and THEN as I think about it, it makes my heart race!). I've also noticed increased muscle spasms as well as extreme and intense pressure on my jaw (TMJ). MY QUESTION IS: does anyone have any experience LOWERING their Adderall dosage AND adding Nuvigil? The research I've done to date gives me impression that it could help balance out the more extreme effects of Adderall (60mg/day) but that the nuvigil would or could potentially help with the EXTREME exhaustion I feel as Adderall wears off. Some days I just crash, some days I sleep fine and others no matter how hard I tryyyy, I just CAN'T fall asleep, therefore making the next day worse! IDEALLY I'D LIKE TO BE MED FREE, right now I need them, but am hoping maybe I can speak with my doctor to lower Adderall and add Nuvigil to help wean me off the amphetamines as well as lower dosage intake. YES, a lot of the anxiety, sleeplessness and depression are related to current circumstances in my life, however, where I am is not where I want to be or where I'm headed.. Life is a journey, and all my meds have become a part of a journey I never thought I'd find myself taking. I don't want life/meds to define me, or create a me I no longer recognize, because scarily enough that seems to be a common pattern. As I overcome each and every daily obstacle, I also don't want to be "hooked" on my meds or needing "more" to wake up/sleep/function.. I'd like to work on finding a solution towards weaning off my meds NOW, and work my way off slowly, primarily the Adderall. I'm hoping by suggesting to my doctor and showing him my research he may agree (IF ITS EVEN A LOGICAL COMBO, CLEARLY IM NOT A DOCTOR) nuvigil could help me. I've already started taking less of my anti depressants, trazadone and xanax without discussing with doc because he is always busy.. My next appt I want to go in fully prepared with a plan and an overall goal to REDUCE my Adderall dose, but overall, I'm clueless!!! I have no idea what other meds other than nuvigil "could" potentially help if at all. I could be entirely wrong, Anyone with any experience using one vs other or both simultaneously, or anyone with constructive input, PLEASE COMMENT/SHARE!!
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Comments from related studies:
From this study (2 years ago):
Carmen on May, 4, 2012:
My experience with Depo has been a nightmare/horror story that seems to never end. I physically look and feel different compared to before my shot. First let me say that I took this shot a few times when I was about 17/18 years old. Didn't 'think' I had any side effects back then.... Had the shot for the first time since then back in September of 2010....NEVER AGAIN! Let me add to the past by saying now with all of the side effects I began experiencing within 2 weeks of that September 2010 shot, I now realize I DID have side effects when I was younger, I just didn't realize it then. My whole life my vision was 20/20 until I was about 18/19/20. My eyes began bothering me, felt blurry all the time, was having alot of headaches. Found out I suddenly had a stigmatism that I never had before. I've had circulation problems all through my 20's. So fast forward....2 weeks after my shot in September of 2010, I began experiencing horrifying hair changes and I began bleeding. It was 'that time of the month' after that every single day through January of 2011. Yes, 4-5 months of bleeding every day!
Carmen on May, 4, 2012:
(The rest of my comment continued from above) My hair? My hair became extremely extremely disgustingly greasy and slowly became thinner and thinner. Before that, my hair was beautiful, thick, naturally curly/wavy. The kind of hair that I could wear curly or straighten with a flat iron. Once I finally realized the cause, I didnt' go back for my second shot! I realized when researching my hair issues....I was HORRIFIED! Also at that time...I had lost all of my pregnancy weight from giving birth to twins just 7 months before this. That August I was teeny tiny. I ate right and exercised all of that pregnancy weight off. My whole life I never ever had problems with my weight. After a baby I would lose the weight if I ate right and exercised. Well, within the first 6 months of depo for me, I gained 10-20 pounds. Ok, so I tried to stop my hair problems. I'm still fighting these problems almost 2 years after that shot. I have some other health issues that I wonder if it could be related to the shots when I was younger. Heart issues, breathing issues, back issues. The back issues just started this past year. Where it's hard for me to sit up straight. Fast forward to now. I've managed to control my hair even though it will never be the same again. I use organic shampoos only, preferably anything with Green Tea. It helps a lot if you have this problem with oily hair which I NEVER had until 2 weeks after that shot in September! My hair texture has also changed like someone else commented. My hair seems stringy and dry now, along with a little bit oily inspite of the organic shampoo that thankfully helps because it could be so much worse! At one point I avoided conditioner for almost a year!
Carmen on May, 4, 2012:
(sorry, there was more to my comment....continued from above...this is it though :) Before this experience my hair was the opposite, I would struggle to tame my mane because it was so thick, etc. As for my weight, I am disgusted. No matter how hard I try, I can't seem to lose this 10-15 pounds. I lost 5 or so but can't get the rest off. I want to vomit when I look at myself. I'm also severely bloated ALLL day no matter how much or little I eat! It seems like I gain weight just from breathing! Mood problems. I already have mood issues, so this shot made them worse. That is pretty much under control now though. Within the past year, I also started having problems with my legs, bad circulation problems through my whole body with veins. Even my arms. But my legs also had bad edema at one point. I take Horsechestnut and it helps my circulation a lot. If I miss a pill my legs ache. My legs were in a lot of pain. My knees started bothering me a lot too, I can feel what my mother says sounds like 'calcium deposits'....a strange noise my knees make. Like a popping noise? when I move them a certain way. Not all the time. I started taking Tums as a calcium supplement recently too. Another thing I do with my hair is I take a prenatal vitamin...it helps with the hair loss problem!!! Helped a lot actually. I feel like I look really old and terrible lately. This didn't start until after the depo. Hopefully I will be able to get back to the old me....my weight and hair make me want to cry sometimes because I'm trying and trying but my hair is just not the same. My belly looks like I'm 3 months pregnant sometimes from the bloating. Doesn't make you feel so pretty.... :(
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