Review: could Depo-provera cause Depression?


Summary

Depression is found among people who take Depo-Provera, especially for people who are female, 20-29 old , have been taking the drug for < 1 month, also take medication Accutane, and have Contraception . We study 11,162 people who have side effects while taking Depo-provera from FDA and social media. Among them, 578 have Depression. Find out below who they are, when they have Depression and more.

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Depo-provera

Depo-provera has active ingredients of medroxyprogesterone acetate. It is often used in birth control. (latest outcomes from Depo-provera 12,339 users)

Depression

Depression has been reported by people with suicidal ideation, pain, drug ineffective, insomnia, fatigue (latest reports from 355,810 Depression patients).

On Sep, 14, 2016

11,162 people reported to have side effects when taking Depo-provera.
Among them, 578 people (5.18%) have Depression


Number of reports submitted per year:

Could Depo-provera cause Depression?

Time on Depo-provera when people have Depression *:

  • < 1 month: 55.51 %
  • 1 - 6 months: 13.31 %
  • 6 - 12 months: 4.18 %
  • 1 - 2 years: 4.94 %
  • 2 - 5 years: 9.51 %
  • 5 - 10 years: 10.65 %
  • 10+ years: 1.9 %

Gender of people who have Depression when taking Depo-provera *:

  • female: 97.88 %
  • male: 2.12 %

Age of people who have Depression when taking Depo-provera *:

  • 0-1: 0.43 %
  • 2-9: 0.0 %
  • 10-19: 15.05 %
  • 20-29: 37.63 %
  • 30-39: 33.12 %
  • 40-49: 10.97 %
  • 50-59: 1.51 %
  • 60+: 1.29 %

Severity if Depression when taking Depo-provera **:

  • least: 7.69 %
  • moderate: 53.85 %
  • severe: 23.08 %
  • most severe: 15.38 %

How people recovered from Depression **:

  • while on drug: 25 %
  • after off the drug: 25 %
  • not yet: 50 %

Top conditions involved for these people *:

  • Contraception (276 people, 47.75%)
  • Endometriosis (34 people, 5.88%)
  • Acne (28 people, 4.84%)
  • Depression (21 people, 3.63%)
  • Anxiety (20 people, 3.46%)

Top co-used drugs for these people *:

  • Accutane (44 people, 7.61%)
  • Mirena (41 people, 7.09%)
  • Effexor (30 people, 5.19%)
  • Topamax (27 people, 4.67%)
  • Lexapro (25 people, 4.33%)

Top other side effects for these people *:

  • Anxiety (165 people, 28.55%)
  • Weight Increased (163 people, 28.20%)
  • Headache (111 people, 19.20%)
  • Suicidal Ideation (100 people, 17.30%)
  • Fatigue (98 people, 16.96%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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