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Review: could Dexamethasone cause Adrenal insufficiency?

Summary: Adrenal insufficiency could be caused by Dexamethasone, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months, also take Hydrocortisone, and have Multiple myeloma.

We study 53,148 people who have side effects while taking Dexamethasone from FDA and social media. Among them, 130 have Adrenal insufficiency. Find out below who they are, when they have Adrenal insufficiency and more.

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On Apr, 9, 2014: 53,148 people reported to have side effects when taking Dexamethasone. Among them, 130 people (0.24%) have Adrenal Insufficiency. They amount to 0.65% of all the 20,099 people who have Adrenal Insufficiency on eHealthMe.

Trend of Adrenal insufficiency in Dexamethasone reports

Time on Dexamethasone when people have Adrenal insufficiency * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Adrenal insufficiency16.67%50.00%0.00%33.33%0.00%0.00%0.00%

Gender of people who have Adrenal insufficiency when taking Dexamethasone * :

FemaleMale
Adrenal insufficiency55.07%44.93%

Age of people who have Adrenal insufficiency when taking Dexamethasone * :

0-12-910-1920-2930-3940-4950-5960+
Adrenal insufficiency5.07%5.07%2.17%5.80%12.32%18.84%5.07%45.65%

Severity of Adrenal insufficiency when taking Dexamethasone ** :

n/a

How people recovered from Adrenal insufficiency ** :

n/a

Top conditions involved for these people * :

  1. Multiple myeloma (20 people, 15.38%)
  2. Constipation (20 people, 15.38%)
  3. Pain (19 people, 14.62%)
  4. Deep vein thrombosis (16 people, 12.31%)
  5. Pulmonary embolism (14 people, 10.77%)

Top co-used drugs for these people * :

  1. Hydrocortisone (34 people, 26.15%)
  2. Carboplatin (23 people, 17.69%)
  3. Prednisone (21 people, 16.15%)
  4. Naproxen (21 people, 16.15%)
  5. Decadron (20 people, 15.38%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

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On eHealthMe, Dexamethasone (dexamethasone) is often used for multiple myeloma. Find out below the conditions Dexamethasone is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

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Comments from related studies:

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  • Developed symptoms of hyperventation syndrome (need to take frequent deep satisfying deep breaths- not rapid breathing) after hospital stay for flu and possible meningitis. My chest x ray and CBC is normal. One doc tried to tell me this was PTSD/anxiety from post hospitalization. It is not. I am not anxious except for fact that I cannot breath right. I do not have pneumonia. I have never had this before, but I'm even short of breath while talking to people and distracted - still needing to take deep breaths mid conversation. I have never had some of the above drugs before and wondered if they could have anything to do with it. Thank you.

    Reply

    srandall on Mar, 13, 2014:

    I am a Caucasian female age 42. On vanco 3rd time for 3weeks this time. First week this time can't breathe normally, stays n cat scan clear, ringing, popping in ears n loss of hearing, frequent urination and way more urine volume. Dr Denys any of these symptoms from vanco as he gives lectures on vanco. I also had kidney function decreases n he says he would prescribe even if kidneys in half failure because vanco is the best! Sending him documents from Mayo saying after 10 days on vanco patients need to be monitored for hearing, kidney and shallow breathing. Maybe he can add to his lectures.

    Reply

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