Review: could Diflucan cause Tonic Seizures?


Tonic seizures is found among people who take Diflucan, especially for people who are female, 10-19 old , have been taking the drug for < 1 month, also take medication Methotrexate, and have Graft versus host disease . We study 19,937 people who have side effects while taking Diflucan from FDA and social media. Among them, 9 have Tonic seizures. Find out below who they are, when they have Tonic seizures and more.

Personalized health information

On eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA and social media since 1977. Our tools are free and anonymous. 86 million people have used us. 300+ peer-reviewed medical journals have referenced our original studies. Start now >>>


Diflucan has active ingredients of fluconazole. It is often used in vaginal yeast infection. (latest outcomes from Diflucan 20,809 users)

Tonic Seizures

Tonic seizures (all the muscles to suddenly become stiff) has been reported by people with epilepsy, depression, pain, seizures, generalized tonic-clonic seizure (latest reports from 284 Tonic seizures patients).

On Oct, 24, 2016

19,937 people reported to have side effects when taking Diflucan.
Among them, 9 people (0.05%) have Tonic Seizures

Number of reports submitted per year:

Could Diflucan cause Tonic seizures?

Time on Diflucan when people have Tonic Seizures *:

  • < 1 month: 75 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 25 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Tonic Seizures when taking Diflucan *:

  • female: 100 %
  • male: 0.0 %

Age of people who have Tonic Seizures when taking Diflucan *:

  • 0-1: 0.0 %
  • 2-9: 11.11 %
  • 10-19: 66.67 %
  • 20-29: 22.22 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

Top conditions involved for these people *:

  • Graft Versus Host Disease (2 people, 22.22%)

Top co-used drugs for these people *:

  • Methotrexate (7 people, 77.78%)
  • Prednisolone (5 people, 55.56%)
  • Cyclosporine (5 people, 55.56%)
  • Sandimmune (4 people, 44.44%)
  • Prograf (3 people, 33.33%)

Top other side effects for these people *:

  • Encephalopathy Nos (7 people, 77.78%)
  • Headache Nos (6 people, 66.67%)
  • Gastrointestinal Haemorrhage Nos (6 people, 66.67%)
  • Depressed Level Of Consciousness (6 people, 66.67%)
  • Cardiac Tamponade (6 people, 66.67%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Tonic seizures when taking Diflucan?

Browse all side effects of Diflucan

a b c d e f g h i j k l m n o p q r s t u v w x y z

Drugs that are associated with Tonic seizures

Tonic seizures

Could your condition cause Tonic seizures

Tonic seizures

Related studies

Can you answer these questions?

More questions for: Diflucan, Tonic seizures

You may be interested in these reviews

More reviews for: Diflucan, Tonic seizures

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.