Review: could Diphenhydramine Hydrochloride cause Tremor?


Tremor is found among people who take Diphenhydramine Hydrochloride, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Acetaminophen, and have Insomnia . We study 2,096 people who have side effects while taking Diphenhydramine hydrochloride from FDA and social media. Among them, 42 have Tremor. Find out below who they are, when they have Tremor and more.

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Diphenhydramine Hydrochloride

Diphenhydramine hydrochloride has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia. (latest outcomes from Diphenhydramine hydrochloride 3,471 users)


Tremor (trembling or shaking movements in one or more parts of your body) has been reported by people with fever, pain, weakness, chest pain, fatigue (latest reports from 71,620 Tremor patients).

On Aug, 25, 2016

2,096 people reported to have side effects when taking Diphenhydramine Hydrochloride.
Among them, 42 people (2.0%) have Tremor

Number of reports submitted per year:

Could Diphenhydramine hydrochloride cause Tremor?

Time on Diphenhydramine Hydrochloride when people have Tremor *:

  • < 1 month: 72.22 %
  • 1 - 6 months: 5.56 %
  • 6 - 12 months: 5.56 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 16.67 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Tremor when taking Diphenhydramine Hydrochloride *:

  • female: 73.17 %
  • male: 26.83 %

Age of people who have Tremor when taking Diphenhydramine Hydrochloride *:

  • 0-1: 0.0 %
  • 2-9: 2.94 %
  • 10-19: 20.59 %
  • 20-29: 2.94 %
  • 30-39: 14.71 %
  • 40-49: 17.65 %
  • 50-59: 8.82 %
  • 60+: 32.35 %

Severity if Tremor when taking Diphenhydramine Hydrochloride **:

  • least: 0.0 %
  • moderate: 66.67 %
  • severe: 33.33 %
  • most severe: 0.0 %

How people recovered from Tremor **:

  • while on drug: 0.0 %
  • after off the drug: 0.0 %
  • not yet: 100 %

Top conditions involved for these people *:

  • Insomnia (13 people)
  • Depression (9 people)
  • Urinary Tract Infection (4 people)
  • Fluid Intake Reduced (4 people)
  • Cytomegalovirus Infection (4 people)

Top co-used drugs for these people *:

  • Acetaminophen (10 people)
  • Zometa (7 people)
  • Zolpidem Tartrate (7 people)
  • Paxil (7 people)
  • Levofloxacin (7 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Tremor when taking Diphenhydramine hydrochloride?

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