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Review: could Diphenhydramine cause Muscle twitching?

We study 2,026 people who have side effects while taking Diphenhydramine from FDA and social media. Among them, 7 have Muscle twitching. Find out below who they are, when they have Muscle twitching and more.

Stay connected: join a mobile support group for people who take Diphenhydramine hydrochloride and have Muscle twitching >>>

Diphenhydramine hydrochloride

Diphenhydramine hydrochloride (latest outcomes from 2,983 users) has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia.

Muscle twitching

Muscle twitching (latest reports from 61,837 patients) has been reported by people with depression, pain, multiple sclerosis, stress and anxiety, high blood pressure.

On Aug, 15, 2014: 2,022 people reported to have side effects when taking Diphenhydramine hydrochloride. Among them, 7 people (0.35%) have Muscle Twitching. They amount to 0.01% of all the 61,813 people who have Muscle Twitching on eHealthMe.

Trend of Muscle twitching in Diphenhydramine hydrochloride reports

Time on Diphenhydramine hydrochloride when people have Muscle twitching * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Muscle twitching40.00%20.00%0.00%20.00%20.00%0.00%0.00%

Gender of people who have Muscle twitching when taking Diphenhydramine hydrochloride * :

FemaleMale
Muscle twitching100.00%0.00%

Age of people who have Muscle twitching when taking Diphenhydramine hydrochloride * :

0-12-910-1920-2930-3940-4950-5960+
Muscle twitching0.00%0.00%0.00%50.00%33.33%0.00%0.00%16.67%

Severity of Muscle twitching when taking Diphenhydramine hydrochloride ** :

leastmoderateseveremost severe
Muscle twitching20.00%60.00%20.00%0.00%

How people recovered from Muscle twitching ** :

while on the drugafter off the drugnot yet
Muscle twitching0.00%0.00%100.00%

Top conditions involved for these people * :

  1. Chronic insomnia (2 people, 28.57%)
  2. Ankle pain (1 people, 14.29%)
  3. Itching (1 people, 14.29%)
  4. Back pain - nonspecific (1 people, 14.29%)
  5. Muscle contractions involuntary (1 people, 14.29%)

Top co-used drugs for these people * :

  1. Lamictal (2 people, 28.57%)
  2. Pepcid (1 people, 14.29%)
  3. Nitro-dur (1 people, 14.29%)
  4. Diphenhydramine hydrochloride inj (1 people, 14.29%)
  5. Lisinopril and hydrochlorothiazide (1 people, 14.29%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Get connected! Join a mobile support group to help out with your experience or learn from others anytime and anywhere:
- group for people who take Diphenhydramine hydrochloride and have Muscle Twitching
- group for people who take Diphenhydramine hydrochloride
- group for people who have Muscle Twitching

Comments from related studies:

  • From this study (2 months ago):

  • Itching in extremeties with no rash apparent. Eyes watery and burning. Twitching is in left eyelid. Itching started 8 days ago. Lotion does not help much. Diphenhydramine does not help much.

    Reply

  • From this study (2 months ago):

  • These are the only two medications I took for years every day, sometimes more than is directed.

    Reply

  • From this study (2 years ago):

  • I think my daughter is addicted to these meds. She has muscle severe uncontrolled muscle twitching. Sleeps a lot at times and is fatigued. She is also uninterested in daily responsiblilities at times. Erratic.

    Reply

    Dan L. on Oct, 15, 2012:

    the twitching might be tourette symdrome

    Reply

Can you answer these questions (what is this?):

More questions for: Diphenhydramine hydrochloride, Muscle twitching

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    my daughter 14 years old had some problems with dizziness. the doctor felt it was due to anxiety. so he gave her paroxetine. she started the medication and she complain that head hurt . she took it for three weeks and on fourth week she was in school and started shaking arms. than was taken to nurse ...

  • Leg pain and occasional arm and hand pain
    I started having leg pains at night, lower leg felt like the muscle and bone were being pulled causing sharp pain. It was relieved by getting up and walking but would last most of the night. I finally realized after suffering this over and over for months, that it only happened when I had taken be ...

More reviews for: Diphenhydramine hydrochloride, Muscle twitching

On eHealthMe, Diphenhydramine Hydrochloride (diphenhydramine hydrochloride) is often used for insomnia. Find out below the conditions Diphenhydramine Hydrochloride is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Diphenhydramine Hydrochloride used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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