Review: could Enbrel cause Drug withdrawal syndrome?
Summary: Drug withdrawal syndrome is found among people who take Enbrel, especially for people who are female, 50-59 old, have been taking the drug for 1 - 6 months, also take medication Oxycontin, and have Rheumatoid arthritis.
We study 174,980 people who have side effects while taking Enbrel from FDA and social media. Among them, 33 have Drug withdrawal syndrome. Find out below who they are, when they have Drug withdrawal syndrome and more.
You are not alone: join a mobile support group for people who take Enbrel and have Drug withdrawal syndrome >>>
Enbrel has active ingredients of etanercept. It is often used in rheumatoid arthritis. (latest outcomes from 175,543 Enbrel users)
Drug withdrawal syndrome
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation) has been reported by people with depression, pain, stress and anxiety, ill-defined disorder, muscle spasticity. (latest reports from 32,678 Drug withdrawal syndrome patients)
On Feb, 25, 2015: 174,980 people reported to have side effects when taking Enbrel. Among them, 33 people (0.02%) have Drug Withdrawal Syndrome.
Time on Enbrel when people have Drug withdrawal syndrome * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
|Drug withdrawal syndrome||0.00%||37.50%||25.00%||0.00%||37.50%||0.00%||0.00% |
Gender of people who have Drug withdrawal syndrome when taking Enbrel * :
|Drug withdrawal syndrome||67.57%||32.43% |
Age of people who have Drug withdrawal syndrome when taking Enbrel * :
|Drug withdrawal syndrome||0.00%||0.00%||0.00%||0.00%||23.08%||11.54%||53.85%||11.54% |
Top conditions involved for these people * :
- Rheumatoid arthritis (4 people, 12.12%)
- Psoriasis (3 people, 9.09%)
- Psoriatic arthropathy (3 people, 9.09%)
- Depression (3 people, 9.09%)
- Ankylosing spondylitis (3 people, 9.09%)
Top co-used drugs for these people * :
- Oxycontin (12 people, 36.36%)
- Methotrexate (11 people, 33.33%)
- Oxycodone hcl (10 people, 30.30%)
- Sulfasalazine (9 people, 27.27%)
- Prilosec (9 people, 27.27%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
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- Hair loss with enbrel
I have been on Enbrel for 4 months and started seeing significant hair thinning at the second month of treatments (50 mg once per week). My Rhuematologist suggested 800 mcg of folic acid. I am still losing hair although I am feeling so much better.
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I have been on Etanercept for 8 years for Psoriasis. Previous to this I was on
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This Drug has been my saving grace.
- Humira: my experience
I have had some form of arthritis probably since birth. My father and maternal grandfather had some form of arthritis. I began to realize pain in both ankles if I stood or walked too long.
I began taking many NSAIDs when I was around 22. I've done gold, prednisone (twice), plaquenil, butazoidin, sulfasalazine, etc. My best results came with methotrexate after I got cellulitis in my knee (scratch it while kayaking in the summer, fiberglass boat). It dropped my sed rate from over 100 to 35 or so within a few months. I continued with MTX from 1977 to 2000 when my MD suggested Enbrel and stopping MTX. That was a VERY bad decision. Enbrel appeared to mask the disease for a few years. I had my left MCP replaced in 2004, my right heel debrided in 2010, and both my TMJs replaced in 2012. I strongly believe that if I had kept with the MTX it would have delayed those changes. Additionally, in 2011 I was in a bus crash returning from RAGBRAI. I got knocked out from three to six minutes. I had a nasty concussion that lasted 2+ years. Towards the end of the third year post accident I started exercising more aggressively. After doing several 40, 50, and 60 miles rides, I took a leisurely 50 mile ride around Boston at night. Two days later I had a spinal edema. So much for biking and other active sports! :-(
I have continued with MTX. Late 2013 my MD increased my MTX to .8/week. I had been taking .6/week. I stopped taking Enbrel and switched to Humira in early 2014. I took it for a few months before my doc and I realized it was not doing any better than Enbrel. I tried Humira for three months but it did not seem to work any better than Enbrel. In early June I stopped Humira and waited a few weeks before I started Otezla. I stopped Oterzla on 9/15/14 because it made me depressed and allowed my morning stiffness to get much worse.
I started prednisone again from the start of July. By mid-August I told my MD that I was screaming louder than I ever had; my dog was very startled. I stopped it gradually over the next two weeks. Meanwhile, the Otezla made me feel awful.
My MD is going to get me onto another injectable that I take monthly. I forget its name.
- Vasculitis from enbrel
I have deep scars on my legs from vasculitis. This was caused by Enbrel. Initially no one would connect the two: per my rheumatologist 'no one has ever reported vasculitis as a side effect of enbrel.' (2003)
I had to suspend the enbrel for 8 weeks in preparation for complex abdominal surgery. The vasculitis started to heal. Several weeks after the surgery I resumed enbrel and the vasculitis returned by the second or third enbrel shot. The Dr was reluctantly willing to concede that 'it may have been the enbrel.'
The vasculitis was horrific. I've never felt so much pain, pain that wasn't abated in the least by pain medicine. My dermatologist describe it as being equivalent to a third degree burn: the skin dies, nerves start to regenerate but aren't protected by the dermis.
The scars look like I had flesh torn from my legs that didn't quite 'fill in.'
Rheumatologists are too pushy about these biological medicines. They brush past even the most serious side effects. Anything for mobility... I'd prefer not to skip to dialysis sessions or treatment for other organ failure!
- Side effects enbrel developed viral vestibular neuritis
Was on Enbrel 14 years. 10/31/13 Had been hospitalized 7 days severe Viral Vestibular Neuritis. Was given high dose steroids Iv developed Afib as result steroids. On Valtrex 500mg Tid for 1 year. No more Enbrel
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