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Review: could Enbrel cause Gastrointestinal disorder?

We study 174,917 people who have side effects while taking Enbrel from FDA and social media. Among them, 235 have Gastrointestinal disorder. Find out below who they are, when they have Gastrointestinal disorder and more.

Stay connected: join a mobile support group for people who take Enbrel and have Gastrointestinal disorder >>>

Enbrel

Enbrel (latest outcomes from 175,480 users) has active ingredients of etanercept. It is often used in rheumatoid arthritis.

Gastrointestinal disorder

Gastrointestinal disorder (functional problems of gastrointestinal tract) (latest reports from 105,958 patients) has been reported by people with acne, osteoporosis, multiple sclerosis, high blood pressure, depression.

On Jul, 27, 2014: 174,917 people reported to have side effects when taking Enbrel. Among them, 235 people (0.13%) have Gastrointestinal Disorder. They amount to 0.22% of all the 105,956 people who have Gastrointestinal Disorder on eHealthMe.

Trend of Gastrointestinal disorder in Enbrel reports

Time on Enbrel when people have Gastrointestinal disorder * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Gastrointestinal disorder6.56%26.23%16.39%16.39%21.31%9.84%3.28%

Gender of people who have Gastrointestinal disorder when taking Enbrel * :

FemaleMale
Gastrointestinal disorder75.92%24.08%

Age of people who have Gastrointestinal disorder when taking Enbrel * :

0-12-910-1920-2930-3940-4950-5960+
Gastrointestinal disorder0.00%0.00%0.54%1.62%9.19%8.65%30.81%49.19%

Severity of Gastrointestinal disorder when taking Enbrel ** :

n/a

How people recovered from Gastrointestinal disorder ** :

n/a

Top conditions involved for these people * :

  1. Rheumatoid arthritis (106 people, 45.11%)
  2. Ankylosing spondylitis (23 people, 9.79%)
  3. Psoriasis (15 people, 6.38%)
  4. Psoriatic arthropathy (11 people, 4.68%)
  5. Hypertension (7 people, 2.98%)

Top co-used drugs for these people * :

  1. Methotrexate (67 people, 28.51%)
  2. Prednisone (47 people, 20.00%)
  3. Folic acid (21 people, 8.94%)
  4. Humira (18 people, 7.66%)
  5. Alendronate sodium (12 people, 5.11%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

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Comments from related studies:

  • From this study (2 days ago):

  • I have been on Enbrel 50 mg per wk for just over 1 yr. In April 2014, I was awaiting my shipment of meds via UPS, when they arrived I was in the restroom and was unable to get to the door in time. The UPS driver left a note that they would return tomorrow with my box. The next day the UPS driver arrived with my shipment and I met him outside, my first question was, "Where was this box kept last night" he responded "In our Camp Verde wharehouse" I asked if it was refrigerated? The driver responded, "No, UPS does not have that ability". Yet the top of the box has a picture of a penguin on it that says "MUST BE REFRIGERATED!" I pointed to it and said "Do you not see this - this is medication that has to be refrigerated!" Again the driver said, "UPS does not have that ability so we had to put it in our warehouse" I asked is it a refrigerated warehouse?" He said "OH no, it gets about 120 degrees in there". I brought the box in and called Obriova (the pharmacy I get it from) and told them what had happened and they told me to open the box and feel the actual clickpens and check the ice bags placed on top and bottom. The ice bag on top was totally melted and the ice bag on botton had one tiny piece of ice left in it and the clickpens felt room temperature. The pharmacy told me "It should be fine - go ahead and accept it." So I did. I used the first clickpen from this shipment on 4/21/2014. On 4/22/2014 I have severe diarrhea. I returned the remaining 3 clickpens to the pharmacy (due to the diarrhea) and they sent me a new box. Problem is, I still have chronic diarrhea - today is 7/5/2014. My Rheumatologist told me over the phone, "It has nothing to do with the Enbrel". I had a colonoscopy on 6/13/2014, they found multiple small ulcers in my stomach, did 3 biopsies and those came back normal. Actually the diarrhea has gotten worse, to the point where I have to wear Depends to even go out of the house. My bottom is RAW and there is only one gastroenterologist in this town and she can't see me until Sept. I am down to 100 lbs and no one seems to think this is a problem - Could it be the Enbrel? I find it strange that this started the day after I took that shot when it was left in 120 degrees in a warehouse in Arizona......helpless in Arizona.

    Reply

  • From this study (1 week ago):

  • My doctor wants me to try Orencia, but I'm not certain the Enbrel isn't still working. I have concerns about trying a totally different medication.

    Reply

  • From this study (2 weeks ago):

  • Starting to develop a fairly florid reaction to my underwear so I suspect it is due to the latex?

    Reply

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On eHealthMe, Enbrel (etanercept) is often used for rheumatoid arthritis. Find out below the conditions Enbrel is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

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