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Review: could Enbrel cause Gastrointestinal disorder?

Summary: Gastrointestinal disorder is found among people who take Enbrel, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months, also take medication Methotrexate, and have Rheumatoid arthritis.

We study 174,980 people who have side effects while taking Enbrel from FDA and social media. Among them, 235 have Gastrointestinal disorder. Find out below who they are, when they have Gastrointestinal disorder and more.

You are not alone: join a mobile support group for people who take Enbrel and have Gastrointestinal disorder >>>

 

 

 

 

Enbrel

Enbrel has active ingredients of etanercept. It is often used in rheumatoid arthritis. (latest outcomes from 175,547 Enbrel users)

Gastrointestinal disorder

Gastrointestinal disorder (functional problems of gastrointestinal tract) has been reported by people with acne, osteoporosis, multiple sclerosis, high blood pressure, depression. (latest reports from 27,552 Gastrointestinal disorder patients)

On Feb, 10, 2015: 174,971 people reported to have side effects when taking Enbrel. Among them, 235 people (0.13%) have Gastrointestinal Disorder.

Trend of Gastrointestinal disorder in Enbrel reports

Time on Enbrel when people have Gastrointestinal disorder * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Gastrointestinal disorder6.56%26.23%16.39%16.39%21.31%9.84%3.28%

Gender of people who have Gastrointestinal disorder when taking Enbrel * :

FemaleMale
Gastrointestinal disorder75.92%24.08%

Age of people who have Gastrointestinal disorder when taking Enbrel * :

0-12-910-1920-2930-3940-4950-5960+
Gastrointestinal disorder0.00%0.00%0.54%1.62%9.19%8.65%30.81%49.19%

Severity of Gastrointestinal disorder when taking Enbrel ** :

n/a

How people recovered from Gastrointestinal disorder ** :

n/a

Top conditions involved for these people * :

  1. Rheumatoid arthritis (106 people, 45.11%)
  2. Ankylosing spondylitis (23 people, 9.79%)
  3. Psoriasis (15 people, 6.38%)
  4. Psoriatic arthropathy (11 people, 4.68%)
  5. Hypertension (7 people, 2.98%)

Top co-used drugs for these people * :

  1. Methotrexate (67 people, 28.51%)
  2. Prednisone (47 people, 20.00%)
  3. Folic acid (21 people, 8.94%)
  4. Humira (18 people, 7.66%)
  5. Alendronate sodium (12 people, 5.11%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Gastrointestinal Disorder while taking Enbrel?

You are not alone! Join a mobile support group:
- support group for people who take Enbrel and have Gastrointestinal Disorder
- support group for people who take Enbrel
- support group for people who have Gastrointestinal Disorder

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More questions for: Enbrel, Gastrointestinal disorder

You may be interested at these reviews (Write a review):

  • Having leg cramps after 2 years on enbrel
    Started having leg cramps after using Enbrel for almsot 2 years. They start the day I give the injection and have lasted 1-3 days waking me several time in the middle of the night.
  • Hair loss with enbrel
    I have been on Enbrel for 4 months and started seeing significant hair thinning at the second month of treatments (50 mg once per week). My Rhuematologist suggested 800 mcg of folic acid. I am still losing hair although I am feeling so much better.
  • Etanercept and irritability
    I have been on Etanercept for 8 years for Psoriasis. Previous to this I was on
    Methotrexate, Cyclosporine, Retinodes and ACTH injections.Since being on 25mg twice a week I have been 98% clear.The only side effect to date is "Irritability" which lasts about 24hrs.
    This Drug has been my saving grace.
  • Humira: my experience
    I have had some form of arthritis probably since birth. My father and maternal grandfather had some form of arthritis. I began to realize pain in both ankles if I stood or walked too long.

    I began taking many NSAIDs when I was around 22. I've done gold, prednisone (twice), plaquenil, butazoidin, sulfasalazine, etc. My best results came with methotrexate after I got cellulitis in my knee (scratch it while kayaking in the summer, fiberglass boat). It dropped my sed rate from over 100 to 35 or so within a few months. I continued with MTX from 1977 to 2000 when my MD suggested Enbrel and stopping MTX. That was a VERY bad decision. Enbrel appeared to mask the disease for a few years. I had my left MCP replaced in 2004, my right heel debrided in 2010, and both my TMJs replaced in 2012. I strongly believe that if I had kept with the MTX it would have delayed those changes. Additionally, in 2011 I was in a bus crash returning from RAGBRAI. I got knocked out from three to six minutes. I had a nasty concussion that lasted 2+ years. Towards the end of the third year post accident I started exercising more aggressively. After doing several 40, 50, and 60 miles rides, I took a leisurely 50 mile ride around Boston at night. Two days later I had a spinal edema. So much for biking and other active sports! :-(

    I have continued with MTX. Late 2013 my MD increased my MTX to .8/week. I had been taking .6/week. I stopped taking Enbrel and switched to Humira in early 2014. I took it for a few months before my doc and I realized it was not doing any better than Enbrel. I tried Humira for three months but it did not seem to work any better than Enbrel. In early June I stopped Humira and waited a few weeks before I started Otezla. I stopped Oterzla on 9/15/14 because it made me depressed and allowed my morning stiffness to get much worse.

    I started prednisone again from the start of July. By mid-August I told my MD that I was screaming louder than I ever had; my dog was very startled. I stopped it gradually over the next two weeks. Meanwhile, the Otezla made me feel awful.

    My MD is going to get me onto another injectable that I take monthly. I forget its name.
  • Vasculitis from enbrel
    I have deep scars on my legs from vasculitis. This was caused by Enbrel. Initially no one would connect the two: per my rheumatologist 'no one has ever reported vasculitis as a side effect of enbrel.' (2003)

    I had to suspend the enbrel for 8 weeks in preparation for complex abdominal surgery. The vasculitis started to heal. Several weeks after the surgery I resumed enbrel and the vasculitis returned by the second or third enbrel shot. The Dr was reluctantly willing to concede that 'it may have been the enbrel.'

    The vasculitis was horrific. I've never felt so much pain, pain that wasn't abated in the least by pain medicine. My dermatologist describe it as being equivalent to a third degree burn: the skin dies, nerves start to regenerate but aren't protected by the dermis.

    The scars look like I had flesh torn from my legs that didn't quite 'fill in.'

    Rheumatologists are too pushy about these biological medicines. They brush past even the most serious side effects. Anything for mobility... I'd prefer not to skip to dialysis sessions or treatment for other organ failure!

More reviews for: Enbrel, Gastrointestinal disorder

Comments from related studies:

  • From this study (1 week ago):

  • I am currently experiencing constant muscle contractions in my abdomen and jerking movements in my neck and midsection. My neck will pull back by itself... Or while I'm standing I'll involuntarily bend over. I'm also having balance issues. I feel very unstable walking and am experiencing some tremors.

    Reply

  • From this study (3 weeks ago):

  • started getting red scaly bumps that it on face and hands

    Reply

  • From this study (4 weeks ago):

  • Many autonomic nervous system symptoms with severe body pain and severe fatigue and gastrotestinal disruptions...

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