Enbrel and Kidney failure - from FDA reports


Summary

Kidney failure is found among people who take Enbrel, especially for people who are female, 60+ old , have been taking the drug for 1 - 6 months, also take medication Methotrexate, and have Rheumatoid arthritis . We study 375,857 people who have side effects while taking Enbrel from FDA. Among them, 912 have Kidney failure. Find out below who they are, when they have Kidney failure and more.

What to expect?

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Enbrel

Enbrel has active ingredients of etanercept. It is often used in rheumatoid arthritis. (latest outcomes from Enbrel 377,260 users)

Kidney Failure

Kidney failure (loss of kidney function) has been reported by people with high blood pressure, multiple myeloma, coronary artery bypass, diabetes, rheumatoid arthritis (latest reports from 82,170 Kidney failure patients).

On Jan, 25, 2017

375,857 people reported to have side effects when taking Enbrel.
Among them, 912 people (0.24%) have Kidney Failure


Number of reports submitted per year:

Could Enbrel cause Kidney failure?

Time on Enbrel when people have Kidney Failure *:

  • < 1 month: 11.27 %
  • 1 - 6 months: 23.7 %
  • 6 - 12 months: 14.74 %
  • 1 - 2 years: 15.61 %
  • 2 - 5 years: 19.65 %
  • 5 - 10 years: 12.72 %
  • 10+ years: 2.31 %

Gender of people who have Kidney Failure when taking Enbrel *:

  • female: 62.68 %
  • male: 37.32 %

Age of people who have Kidney Failure when taking Enbrel *:

  • 0-1: 0.0 %
  • 2-9: 0.94 %
  • 10-19: 0.47 %
  • 20-29: 2.04 %
  • 30-39: 3.45 %
  • 40-49: 13.03 %
  • 50-59: 26.84 %
  • 60+: 53.22 %

Top conditions involved for these people *:

  • Rheumatoid Arthritis (541 people, 59.32%)
  • Psoriasis (116 people, 12.72%)
  • Psoriatic Arthropathy (79 people, 8.66%)
  • Ankylosing Spondylitis (58 people, 6.36%)
  • Osteoporosis (42 people, 4.61%)

Top co-used drugs for these people *:

  • Methotrexate (166 people, 18.20%)
  • Prednisone (84 people, 9.21%)
  • Plaquenil (57 people, 6.25%)
  • Lasix (54 people, 5.92%)
  • Nexium (44 people, 4.82%)

Top other side effects for these people *:

  • Pain (112 people, 12.28%)
  • Pneumonia (111 people, 12.17%)
  • Sepsis (81 people, 8.88%)
  • Anaemia (77 people, 8.44%)
  • Diarrhea (74 people, 8.11%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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